acute Leukemia Lecture slides
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Questions and Answers

Which of the following is a type of leukemia mentioned in the text?

  • Chronic myeloid leukemia (correct)
  • Multiple myeloma
  • Hodgkin's lymphoma
  • Breast cancer

    • What is the most common risk factor for acute myeloid leukemia?

  • Exposure to radiation or chemotherapy (correct)
  • Inherited bone marrow failure
  • Environmental risk factors
  • Genetic disorders

    • What are the most important prognostic indicators for acute myeloid leukemia?

  • Gender, race, blood type
  • Education level, income, marital status
  • Family history, body mass index, smoking status
  • Age, cytogenetics, molecular genetics (correct)

    • What is the annual incidence of acute myeloid leukemia in the United States?

    <p>10 per 100,000</p> Signup and view all the answers

    What is the overall survival rate for adults with acute myeloid leukemia?

    <p>Low</p> Signup and view all the answers

    What is the most common type of leukemia in adults?

    <p>Acute myeloid leukemia</p> Signup and view all the answers

    What is the main characteristic of acute myeloid leukemia?

    <p>Accumulation of immature hematopoietic cells</p> Signup and view all the answers

    What is the most common subtype of acute myeloid leukemia according to the WHO 2016 classification?

    <p>M3</p> Signup and view all the answers

    What is the recommended treatment for acute myeloid leukemia in patients less than 60 years of age?

    <p>Chemotherapy</p> Signup and view all the answers

    What is the indication for allogeneic stem cell transplantation in acute myeloid leukemia?

    <p>Intermediate and poor risk disease</p> Signup and view all the answers

    Which type of leukemia is characterized by a balanced reciprocal translocation between chromosomes 15 and 17?

    <p>Acute myeloid leukemia</p> Signup and view all the answers

    Which subtype of leukemia is exquisitely sensitive to ATRA, anthracyclines, and arsenic trioxide?

    <p>Acute promyelocytic leukemia</p> Signup and view all the answers

    What is the cure rate for acute promyelocytic leukemia?

    <p>High</p> Signup and view all the answers

    Which type of leukemia progresses rapidly and is typically fatal within weeks or months if left untreated?

    <p>Acute lymphoblastic leukemia</p> Signup and view all the answers

    What is the most common type of acute leukemia in adults?

    <p>Acute lymphoblastic leukemia</p> Signup and view all the answers

    What is the recommended treatment for acute lymphoblastic leukemia?

    <p>Chemotherapy</p> Signup and view all the answers

    What age group has inferior cure rates for acute lymphoblastic leukemia compared to children?

    <p>Young adults</p> Signup and view all the answers

    What is the indication for allogeneic hematopoietic cell transplantation in acute lymphoblastic leukemia?

    <p>All of the above</p> Signup and view all the answers

    Which genetic abnormality is associated with poor prognosis in acute lymphoblastic leukemia?

    <p>IKZF1 deletion</p> Signup and view all the answers

    When is allogeneic hematopoietic cell transplantation indicated in acute lymphoblastic leukemia?

    <p>All of the above</p> Signup and view all the answers

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