acute Leukemia Lecture slides

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Which of the following is a type of leukemia mentioned in the text?

Chronic myeloid leukemia (correct)

Multiple myeloma

Hodgkin's lymphoma

Breast cancer

What is the most common risk factor for acute myeloid leukemia?

Exposure to radiation or chemotherapy (correct)

Inherited bone marrow failure

Environmental risk factors

Genetic disorders

What are the most important prognostic indicators for acute myeloid leukemia?

Gender, race, blood type

Education level, income, marital status

Family history, body mass index, smoking status

Age, cytogenetics, molecular genetics (correct)

What is the annual incidence of acute myeloid leukemia in the United States?

10 per 100,000 Signup and view all the answers

What is the overall survival rate for adults with acute myeloid leukemia?

Low Signup and view all the answers

What is the most common type of leukemia in adults?

Acute myeloid leukemia Signup and view all the answers

What is the main characteristic of acute myeloid leukemia?

Accumulation of immature hematopoietic cells Signup and view all the answers

What is the most common subtype of acute myeloid leukemia according to the WHO 2016 classification?

M3 Signup and view all the answers

What is the recommended treatment for acute myeloid leukemia in patients less than 60 years of age?

Chemotherapy Signup and view all the answers

What is the indication for allogeneic stem cell transplantation in acute myeloid leukemia?

Intermediate and poor risk disease Signup and view all the answers

Which type of leukemia is characterized by a balanced reciprocal translocation between chromosomes 15 and 17?

Acute myeloid leukemia Signup and view all the answers

Which subtype of leukemia is exquisitely sensitive to ATRA, anthracyclines, and arsenic trioxide?

Acute promyelocytic leukemia Signup and view all the answers

What is the cure rate for acute promyelocytic leukemia?

High Signup and view all the answers

Which type of leukemia progresses rapidly and is typically fatal within weeks or months if left untreated?

Acute lymphoblastic leukemia Signup and view all the answers

What is the most common type of acute leukemia in adults?

Acute lymphoblastic leukemia Signup and view all the answers

What is the recommended treatment for acute lymphoblastic leukemia?

Chemotherapy Signup and view all the answers

What age group has inferior cure rates for acute lymphoblastic leukemia compared to children?

Young adults Signup and view all the answers

What is the indication for allogeneic hematopoietic cell transplantation in acute lymphoblastic leukemia?

All of the above Signup and view all the answers

Which genetic abnormality is associated with poor prognosis in acute lymphoblastic leukemia?

IKZF1 deletion Signup and view all the answers

When is allogeneic hematopoietic cell transplantation indicated in acute lymphoblastic leukemia?