Leprosy Disease

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Questions and Answers

What is the bacterium that causes leprosy?

  • Mycobacterium leprae (correct)
  • Mycobacterium tuberculosis
  • Mycobacterium avium
  • Mycobacterium kansasii

Which of the following is NOT affected by leprosy?

  • Brain (correct)
  • Eyes
  • Skin
  • Upper respiratory tract

What is the characteristic of the skin lesion in leprosy?

  • Itchy and crater-like
  • Scaly and ring-shaped
  • Painful and swollen
  • Blotchy, indurated, and hypopigmented (correct)

What is the result of cell-mediated immunity in leprosy?

<p>It kills the organism and damages nerves (D)</p> Signup and view all the answers

What type of inflammation is seen in leprosy?

<p>Granulomatous inflammation (C)</p> Signup and view all the answers

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Study Notes

Leprosy (Hansen's Disease)

  • Chronic infectious disease caused by slow-growing bacteria Mycobacterium leprae.
  • Affects multiple body parts, including:
    • Skin
    • Peripheral nerves
    • Mucosal surfaces of the upper respiratory tract
    • Eyes
  • Can occur at any age, from early infancy to very old age.

Symptoms

  • Skin lesions:
    • Blotchy
    • Indurated (hardened)
    • Red
    • Anesthesia
    • Hypopigmented center
  • Muscle weakness

Diagnosis and Pathogenesis

  • Lepromin test: positive
  • Cell-mediated immunity: kills the organism, but damages nerves
  • Perivascular/perineural granulomatous inflammation: a characteristic feature of the disease

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