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Questions and Answers
What is the bacterium that causes leprosy?
What is the bacterium that causes leprosy?
- Mycobacterium leprae (correct)
- Mycobacterium tuberculosis
- Mycobacterium avium
- Mycobacterium kansasii
Which of the following is NOT affected by leprosy?
Which of the following is NOT affected by leprosy?
- Brain (correct)
- Eyes
- Skin
- Upper respiratory tract
What is the characteristic of the skin lesion in leprosy?
What is the characteristic of the skin lesion in leprosy?
- Itchy and crater-like
- Scaly and ring-shaped
- Painful and swollen
- Blotchy, indurated, and hypopigmented (correct)
What is the result of cell-mediated immunity in leprosy?
What is the result of cell-mediated immunity in leprosy?
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What type of inflammation is seen in leprosy?
What type of inflammation is seen in leprosy?
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Study Notes
Leprosy (Hansen's Disease)
- Chronic infectious disease caused by slow-growing bacteria Mycobacterium leprae.
- Affects multiple body parts, including:
- Skin
- Peripheral nerves
- Mucosal surfaces of the upper respiratory tract
- Eyes
- Can occur at any age, from early infancy to very old age.
Symptoms
- Skin lesions:
- Blotchy
- Indurated (hardened)
- Red
- Anesthesia
- Hypopigmented center
- Muscle weakness
Diagnosis and Pathogenesis
- Lepromin test: positive
- Cell-mediated immunity: kills the organism, but damages nerves
- Perivascular/perineural granulomatous inflammation: a characteristic feature of the disease
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