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Questions and Answers

What classes of drugs are commonly used to treat hypertension? (Select all that apply)

  • Alpha adrenergic blockers (correct)
  • Diuretics (correct)
  • Angiotensin II receptor blockers (correct)
  • Calcium channel blockers (correct)
  • Beta-blockers (correct)
  • Angiotensin-converting enzyme inhibitors (correct)
  • What is the primary mechanism of action for beta-blockers?

  • Inhibiting the conversion of angiotensin I to angiotensin II, leading to decreased AII and decreased aldosterone
  • Blocking of the beta-adrenergic receptors in the body, thereby decreasing heart rate and blood pressure (correct)
  • Blocking of the alpha-adrenergic receptors in the body, thereby increasing heart rate and blood pressure
  • Blocking the movement of calcium ions across the membranes of myocardial and arterial muscle cells, leading to a decrease in peripheral resistance
  • What is the general name for the common beta-blockers characterized by the '-olol' suffix?

  • The ‘sartans
  • The ‘-dipines’
  • The ‘-olol’s (correct)
  • The ‘-prils
  • What is the prototype drug for the angiotensin-converting enzyme inhibitors?

    <p>Captopril</p> Signup and view all the answers

    Angiotensin II Receptor Blockers (ARBs) specifically bind to which receptors in the body?

    <p>Angiotensin II receptors in the blood vessels and adrenal cortex</p> Signup and view all the answers

    Name one calcium channel blocker that is considered the prototype.

    <p>Nifedipine is a well-established calcium channel blocker that serves as a key reference point for understanding the class and its properties.</p> Signup and view all the answers

    Calcium channel blockers are contraindicated in patients with heart block or sick sinus syndrome.

    <p>True</p> Signup and view all the answers

    What are the main uses for organic nitrates?

    <p>Organic nitrates are primarily used for the treatment of angina, a condition characterized by chest pain due to insufficient blood flow to the heart muscle.</p> Signup and view all the answers

    Nitroglycerin is given sublingually due to a significant first-pass hepatic effect.

    <p>True</p> Signup and view all the answers

    What is the most common effect of nitroglycerin?

    <p>Headache</p> Signup and view all the answers

    What drug is often used to treat hypotension in shock states not caused by hypovolemia?

    <p>Dopamine</p> Signup and view all the answers

    Dopamine administration can cause tissue necrosis if extravasation occurs.

    <p>True</p> Signup and view all the answers

    What are some common antiarrhythmic agents classified under Class 1?

    <p>Encainide, Flecainide, propafenone</p> Signup and view all the answers

    All antiarrhythmic agents are effective in restoring and maintaining normal cardiac rhythm.

    <p>False</p> Signup and view all the answers

    What is the primary effect of digoxin on cardiac function?

    <p>Increased contractility</p> Signup and view all the answers

    What is the therapeutic range for digoxin?

    <p>0.5 to 2.0 nanograms/mL</p> Signup and view all the answers

    Digoxin administration should be done intramuscularly for optimal absorption.

    <p>False</p> Signup and view all the answers

    The main use of calcium channel blockers is for the treatment of:

    <p>Angina</p> Signup and view all the answers

    Vasodilators are contraindicated in pregnant women because they can cause serious adverse effects on the fetus.

    <p>True</p> Signup and view all the answers

    What is the primary way that ACE inhibitors lower blood pressure?

    <p>Block the conversion of angiotensin I to angiotensin II</p> Signup and view all the answers

    What are the three main drug classes commonly used to treat angina?

    <p>Calcium-channel blockers</p> Signup and view all the answers

    Antianginal drugs are considered effective if they relieve chest pain.

    <p>True</p> Signup and view all the answers

    Dopamine is indicated for the treatment of:

    <p>Hypotension in shock states</p> Signup and view all the answers

    All anti-arrhythmic drugs are equally effective in treating arrhythmias.

    <p>False</p> Signup and view all the answers

    Anti-arrhythmic drugs can sometimes cause arrhythmias themselves.

    <p>True</p> Signup and view all the answers

    The goal of anti-arrhythmic therapy is to correct the irregular heartbeat back to a normal rhythm.

    <p>True</p> Signup and view all the answers

    What are some side effects of dopamine? (Select all that apply)

    <p>Tachycardia</p> Signup and view all the answers

    What are the three main drug classes used in congestive heart failure?

    <p>Diuretics</p> Signup and view all the answers

    Cardiotonic drugs increase the level of calcium in the heart muscles, leading to increased contractility.

    <p>True</p> Signup and view all the answers

    Cardiac glycosides are only available in oral preparations.

    <p>False</p> Signup and view all the answers

    Name the two main cardiac glycosides.

    <p>Digitoxin</p> Signup and view all the answers

    What is the most common side effect associated with the use of nitrates?

    <p>Headache</p> Signup and view all the answers

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