Podcast
Questions and Answers
What is the preferred diagnostic test for Cushing disease?
What is the preferred diagnostic test for Cushing disease?
- ACTH stimulation test
- Urine cortisol-to-creatinine ratio
- High-dose dexamethasone suppression test
- Low-dose dexamethasone suppression test (correct)
Which of the following statements about Cushing syndrome is true?
Which of the following statements about Cushing syndrome is true?
- Ectopic ACTH secretion in dogs is commonly associated with lung tumors
- It refers only to pituitary-dependent hyperadrenocorticism
- Iatrogenic hyperadrenocorticism results from insufficient steroid administration
- Pituitary-dependent hyperadrenocorticism is less common than adrenal-dependent disease in dogs (correct)
What is the characteristic age range of dogs affected by Cushing disease?
What is the characteristic age range of dogs affected by Cushing disease?
- 5-7 years old
- 12-15 years old
- 2-5 years old
- 7-12 years old (correct)
Which term encompasses both pituitary-dependent and adrenal-dependent causes of elevated cortisol concentrations?
Which term encompasses both pituitary-dependent and adrenal-dependent causes of elevated cortisol concentrations?
What is the most common disadvantage of the LDDS test in dogs with nonadrenal illness?
What is the most common disadvantage of the LDDS test in dogs with nonadrenal illness?
What is the pattern of suppression and escape seen in 30% of dogs with PDH during an LDDS test?
What is the pattern of suppression and escape seen in 30% of dogs with PDH during an LDDS test?
What diagnostic tool uses three doses of dexamethasone to measure urine cortisol in cats and dogs?
What diagnostic tool uses three doses of dexamethasone to measure urine cortisol in cats and dogs?
What is a possible reason for negative ACTH stimulation and LDDS tests in dogs with adrenal sex steroid excess?
What is a possible reason for negative ACTH stimulation and LDDS tests in dogs with adrenal sex steroid excess?
Why may dynamic adrenal testing be necessary for dogs with adrenal sex steroid excess?
Why may dynamic adrenal testing be necessary for dogs with adrenal sex steroid excess?
Which test is the most reliable way to differentiate between PDH and adrenal tumors in dogs according to the text?
Which test is the most reliable way to differentiate between PDH and adrenal tumors in dogs according to the text?
What is the purpose of adding the protease inhibitor aprotinin to whole blood in EDTA tubes as mentioned in the text?
What is the purpose of adding the protease inhibitor aprotinin to whole blood in EDTA tubes as mentioned in the text?
What is a common manifestation of Cushing disease in cats?
What is a common manifestation of Cushing disease in cats?
Why is SAP seldom increased in cats according to the text?
Why is SAP seldom increased in cats according to the text?
What is the most suitable test to differentiate healthy dogs from those with hyperadrenocorticism according to the text?
What is the most suitable test to differentiate healthy dogs from those with hyperadrenocorticism according to the text?
Which statement about Cushing disease manifestations in cats is false according to the text?
Which statement about Cushing disease manifestations in cats is false according to the text?
What causes polydipsia and polyuria in cats with Cushing disease?
What causes polydipsia and polyuria in cats with Cushing disease?
What is the cause of hyposthenuria in dogs with Cushing disease?
What is the cause of hyposthenuria in dogs with Cushing disease?
Why do dogs with moderate to severe nonadrenal illness show increased UCCR ratios?
Why do dogs with moderate to severe nonadrenal illness show increased UCCR ratios?
What should be done if screening test results for hyperadrenocorticism are inconclusive?
What should be done if screening test results for hyperadrenocorticism are inconclusive?
What should be used as the screening test of choice for canine hyperadrenocorticism according to the text?
What should be used as the screening test of choice for canine hyperadrenocorticism according to the text?
What does an increased UCCR need to be confirmed by according to the text?
What does an increased UCCR need to be confirmed by according to the text?
What is the recommended dosage of mitotane for dogs with PDH?
What is the recommended dosage of mitotane for dogs with PDH?
What symptom should prompt discontinuation of mitotane therapy in dogs with PDH?
What symptom should prompt discontinuation of mitotane therapy in dogs with PDH?
How often should dogs on long-term treatment with mitotane have an examination and ACTH response test?
How often should dogs on long-term treatment with mitotane have an examination and ACTH response test?
What is a possible adverse effect of mitotane at the recommended dosage?
What is a possible adverse effect of mitotane at the recommended dosage?
Which imaging technique is stated as a more sensitive way to identify adrenal tumors?
Which imaging technique is stated as a more sensitive way to identify adrenal tumors?
What is a possible consequence of administering trilostane to dogs?
What is a possible consequence of administering trilostane to dogs?
How often should trilostane be administered to achieve a decrease in glucocorticoid secretion?
How often should trilostane be administered to achieve a decrease in glucocorticoid secretion?
What should be monitored to provide an endpoint for mitotane therapy?
What should be monitored to provide an endpoint for mitotane therapy?
What symptom suggests an expanding pituitary macroadenoma after discontinuation of mitotane?
What symptom suggests an expanding pituitary macroadenoma after discontinuation of mitotane?
What is the cortisol concentration indicating excellent control of Cushing's disease pre-trilostane?
What is the cortisol concentration indicating excellent control of Cushing's disease pre-trilostane?
What is the recommended steroid dose for iatrogenic hyperadrenocorticism, as per the text?
What is the recommended steroid dose for iatrogenic hyperadrenocorticism, as per the text?
Which enzyme does selegiline inhibit in the context of Cushing's disease treatment?
Which enzyme does selegiline inhibit in the context of Cushing's disease treatment?
What is the metastatic rate at the time of surgery for adrenal tumors?
What is the metastatic rate at the time of surgery for adrenal tumors?
What percentage of dogs undergoing unilateral adrenalectomies experience mortality within 1 month after surgery?
What percentage of dogs undergoing unilateral adrenalectomies experience mortality within 1 month after surgery?
Which therapy typically follows radiation treatment of pituitary tumors in dogs and cats?
Which therapy typically follows radiation treatment of pituitary tumors in dogs and cats?
What is the typical recurrence rate after hypophysectomy in dogs with PDH?
What is the typical recurrence rate after hypophysectomy in dogs with PDH?
What is the main effect of dopamine on ACTH release from the pituitary gland?
What is the main effect of dopamine on ACTH release from the pituitary gland?
In cases of dogs with large pituitary tumors showing neurologic signs, what treatment is indicated?
In cases of dogs with large pituitary tumors showing neurologic signs, what treatment is indicated?
'Cyberknife' and 'gamma knife' are mentioned in relation to which medical procedure?
'Cyberknife' and 'gamma knife' are mentioned in relation to which medical procedure?
What can be a complication arising from rapid reversal of hyperadrenocorticism after hypophysectomy?
What can be a complication arising from rapid reversal of hyperadrenocorticism after hypophysectomy?
What is the median survival time for dogs with carcinomas treated with surgical excision?
What is the median survival time for dogs with carcinomas treated with surgical excision?
