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Questions and Answers
What is the brand name of Latanoprost?
What is the brand name of Latanoprost?
What is the drug class of Latanoprost?
What is the drug class of Latanoprost?
Anti-glaucoma, prostaglandin analogue/agonist
What are the indications for Latanoprost?
What are the indications for Latanoprost?
Increases IOP in patients with open-angle glaucoma and ocular hypertension
What is the mechanism of action of Latanoprost?
What is the mechanism of action of Latanoprost?
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What is the recommended route and dosage for Latanoprost?
What is the recommended route and dosage for Latanoprost?
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What are the contraindications for Latanoprost?
What are the contraindications for Latanoprost?
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What are the food/drug interactions for Latanoprost?
What are the food/drug interactions for Latanoprost?
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What are some common side effects of Latanoprost?
What are some common side effects of Latanoprost?
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What are the adverse effects of Latanoprost?
What are the adverse effects of Latanoprost?
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What are the desired outcomes of Latanoprost treatment?
What are the desired outcomes of Latanoprost treatment?
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What patient education should be provided for Latanoprost?
What patient education should be provided for Latanoprost?
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Where does Latanoprost metabolism occur?
Where does Latanoprost metabolism occur?
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Study Notes
Latanoprost Overview
- Brand name for latanoprost is Xalatan.
- Classified as an anti-glaucoma medication and a prostaglandin analogue/agonist.
Indications and Uses
- Primarily indicated for managing increased intraocular pressure (IOP) in patients with open-angle glaucoma.
- Effective in treating ocular hypertension.
Mechanism of Action
- Works by enhancing aqueous humor outflow, thereby reducing IOP.
Administration and Dosage
- Administered as an ophthalmic solution at a concentration of 0.005%.
- Recommended dosage is 1 drop in the evening for adults.
Contraindications
- Not suitable for individuals with hypersensitivity to the drug.
- Should be avoided during pregnancy and in cases of intraocular infections or conjunctivitis.
- Not recommended for patients with closed-angle glaucoma.
Drug Interactions
- Caution when used with eyedrops containing thimerosal.
- It is advised to administer drops 5 minutes apart to avoid interaction.
Side Effects
- Common side effects include darkening of the iris (browning), increased length and thickness of eyelashes, and sensations of a foreign body in the eye.
- Other side effects may include burning and tearing of the eyes.
Adverse Effects
- Potential systemic absorption can lead to respiratory infections, flu-like symptoms, angina, muscle/joint pain, rash, headaches, and fatigue.
Desired Outcomes
- Aims to effectively lower IOP through increased aqueous humor production.
- Overall objective is to alleviate glaucoma symptoms.
Patient Education
- Patients should be informed that iris color may change with usage.
- It is important to remove contact lenses before applying the solution.
- Emphasis on compliance with the medication regimen.
- Recommend positioning with the head flat or slightly raised when administering drops, and placing them in the inner corner of the eye.
Metabolism
- Metabolized in the cornea and liver, signifying routes of clearance from the body.
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Test your knowledge on Latanoprost with these flashcards. Each card covers crucial aspects of the drug, including its brand name, drug class, indications, and mechanism of action. Perfect for students or professionals in pharmacology.
