Latanoprost Flashcards

Questions and Answers

What is the brand name of Latanoprost?

Azopt

Travatan

Xalatan (correct)

Lumigan

What is the drug class of Latanoprost?

Anti-glaucoma, prostaglandin analogue/agonist

What are the indications for Latanoprost?

Increases IOP in patients with open-angle glaucoma and ocular hypertension

What is the mechanism of action of Latanoprost?

Increase aqueous humor outflow, lowering IOP Signup and view all the answers

What is the recommended route and dosage for Latanoprost?

Ophthalmic solution: 0.005%, 1 drop in the evening (adults) Signup and view all the answers

What are the contraindications for Latanoprost?

Hypersensitivity, pregnancy, intraocular infection, conjunctivitis, do not administer to closed-angle glaucoma Signup and view all the answers

What are the food/drug interactions for Latanoprost?

Eyedrops that contain thimerosal; give 5 minutes apart of administration Signup and view all the answers

What are some common side effects of Latanoprost?

Darkens color of iris, increased length and thickness of eyelashes, sensation of foreign body in eye, burning, tearing Signup and view all the answers

What are the adverse effects of Latanoprost?

Systemic absorption: respiratory infection, flu, angina, muscle/joint pain, rash, headache, fatigue Signup and view all the answers

What are the desired outcomes of Latanoprost treatment?

Anti-glaucoma, increase in aqueous humor, lower IOP Signup and view all the answers

What patient education should be provided for Latanoprost?

Iris color may change, remove lenses before instilling solution, compliance is important, administer with head flat/slightly raised, place drops in corner of eye Signup and view all the answers

Where does Latanoprost metabolism occur?

Cornea, liver Signup and view all the answers

Study Notes

Latanoprost Overview

Brand name for latanoprost is Xalatan.
Classified as an anti-glaucoma medication and a prostaglandin analogue/agonist.

Indications and Uses

Primarily indicated for managing increased intraocular pressure (IOP) in patients with open-angle glaucoma.
Effective in treating ocular hypertension.

Mechanism of Action

Works by enhancing aqueous humor outflow, thereby reducing IOP.

Administration and Dosage

Administered as an ophthalmic solution at a concentration of 0.005%.
Recommended dosage is 1 drop in the evening for adults.

Contraindications

Not suitable for individuals with hypersensitivity to the drug.
Should be avoided during pregnancy and in cases of intraocular infections or conjunctivitis.
Not recommended for patients with closed-angle glaucoma.

Drug Interactions

Caution when used with eyedrops containing thimerosal.
It is advised to administer drops 5 minutes apart to avoid interaction.

Side Effects

Common side effects include darkening of the iris (browning), increased length and thickness of eyelashes, and sensations of a foreign body in the eye.
Other side effects may include burning and tearing of the eyes.

Adverse Effects

Potential systemic absorption can lead to respiratory infections, flu-like symptoms, angina, muscle/joint pain, rash, headaches, and fatigue.

Desired Outcomes

Aims to effectively lower IOP through increased aqueous humor production.
Overall objective is to alleviate glaucoma symptoms.

Patient Education

Patients should be informed that iris color may change with usage.
It is important to remove contact lenses before applying the solution.
Emphasis on compliance with the medication regimen.
Recommend positioning with the head flat or slightly raised when administering drops, and placing them in the inner corner of the eye.

Metabolism

Metabolized in the cornea and liver, signifying routes of clearance from the body.

Description

Test your knowledge on Latanoprost with these flashcards. Each card covers crucial aspects of the drug, including its brand name, drug class, indications, and mechanism of action. Perfect for students or professionals in pharmacology.