Laboratory Mouse Behavior
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Questions and Answers

Which behavior is NOT exhibited by laboratory mice according to the text?

  • Nest building
  • Foraging
  • Swimming (correct)
  • Climbing
  • What is a notable difference between BALB/c mice and C57Bl/6 mice, as per the text?

  • Preference for enrichment items
  • Nest building ability (correct)
  • Aggression levels
  • Ultrasonic vocalizations
  • Which strain of laboratory mice is mentioned as more aggressive than C57BL/6 in the text?

  • C57Bl/6
  • DBA/2 (correct)
  • CD-1
  • BALB/c
  • What kind of vocalizations do mice use as communication signals in different social contexts?

    <p>Ultrasonic</p> Signup and view all the answers

    What is thought to influence the differences in behaviors among laboratory mouse strains?

    <p>Genetic factors</p> Signup and view all the answers

    What is the main purpose of ultrasonic vocalizations (USVs) in mice according to the text?

    <p>Facilitation or inhibition of social interactions</p> Signup and view all the answers

    Why do mice generally avoid open spaces and prefer to move along the edge of features in their environment?

    <p>To avoid potential predators using thigmotaxis</p> Signup and view all the answers

    What impact can substandard housing conditions have on laboratory mice, as mentioned in the text?

    <p>Development of abnormal behaviors like aggression and stereotypies</p> Signup and view all the answers

    What is one aspect of housing that can negatively impact the welfare of laboratory mice?

    <p>Use of transparent plastic cages</p> Signup and view all the answers

    Why are transparent plastic cages commonly used in modern laboratory settings?

    <p>To allow easy observation without removing animals from the cage</p> Signup and view all the answers

    Study Notes

    Laboratory Mice Characteristics

    • Laboratory mice are derived from wild mice (Mus musculus) and share similarities with their wild cousins.
    • They are predominantly nocturnal, highly social animals, living in family groups and territories.

    Natural Behaviors

    • Laboratory mice will build nests, burrow, climb, and forage if given the chance, similar to their wild cousins.
    • Providing a living environment that allows natural behaviors improves their welfare.

    Strain-Specific Behaviors

    • Laboratory mouse strains show differences in behavior expression and intensity, thought to be genetically determined and dependent on their origins.
    • Examples of differences include nest building, with BALB/c mice being better nest builders than C57Bl/6 and CD-1 strains.
    • Strains also differ in preference for enrichment items and levels of aggression.

    Communication and Ultrasonic Vocalizations

    • Mice emit ultrasonic vocalizations (USVs) in a wide frequency range of 20–100 Hz for communication in different social contexts.
    • USVs are used to facilitate or inhibit social interactions, not to express negative or positive emotions.

    Daily Activities and Senses

    • As nocturnal animals, mice are most active from dawn to dusk and retreat to shelters during the daytime.
    • They spend their active hours eating, exploring territories, running, climbing, and digging.
    • Mice have poor eyesight but good peripheral vision, relying heavily on their sense of smell and acute hearing.

    Housing and Welfare

    • Housing and husbandry conditions have a major impact on laboratory mice throughout their lives.
    • Physical and social environment can influence welfare and research data quality.
    • Substandard housing conditions can lead to abnormal behaviors, such as increased aggression and stereotypies.
    • Mice prefer to nest away from their urine and faeces, and opaque cages may improve their welfare.

    Neglected Housing Aspects

    • Mice have preferences for nesting away from their waste, but standard laboratory housing doesn't allow for spatial segregation.
    • Cage color can influence anxiety levels and behavior, with mice preferring opaque cages.

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    Description

    Explore the behavior of laboratory mice, including their nocturnal nature, social tendencies, and natural behaviors such as nest-building and foraging. Learn how providing an environment that accommodates these behaviors can enhance their welfare.

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