Laboratory Diagnosis: Virus Identification in Cell Culture
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Questions and Answers

What is the primary mechanism by which enveloped viruses penetrate into a cell?

  • Endocytosis
  • Pinocytosis (viropexis) (correct)
  • Fusion with the cell membrane
  • Exocytosis

    • What is the average number of progeny virions produced within hours after one virion infects a cell?

  • Thousands
  • Millions
  • Dozens
  • Hundreds (correct)

    • During what stage of viral replication are no virus particles detected within the infected cell?

  • Attachment
  • Eclipse period (correct)
  • Transcription
  • Penetration

    • What is required for a virus to infect a cell?

    <p>Surface receptors specific to the virus</p> Signup and view all the answers

    What is the correct order of the steps in viral replication?

    <p>Attachment, Penetration, Transcription, Assembly, Release</p> Signup and view all the answers

    What is the term for the process by which viruses enter cells through the formation of vesicles?

    <p>Pinocytosis</p> Signup and view all the answers

    What is the primary method used to detect the presence of a virus in a patient's specimen?

    <p>Observation of cytopathic effect</p> Signup and view all the answers

    What is the purpose of an antibody-based test in virus identification?

    <p>To identify the type of virus</p> Signup and view all the answers

    What is the characteristic of Negri bodies?

    <p>They are formed in the cytoplasm of infected cells</p> Signup and view all the answers

    What is the significance of IgM in serologic procedures?

    <p>It is used to diagnose a current infection</p> Signup and view all the answers

    What is the purpose of electron microscopy in virus identification?

    <p>To identify viruses that are dangerous to grow in culture</p> Signup and view all the answers

    What is the characteristic of multinucleated giant cells?

    <p>They are formed by several viruses</p> Signup and view all the answers

    Which type of virus acquires its envelope by budding through the nuclear membrane?

    <p>Herpesviruses</p> Signup and view all the answers

    What is the term used to describe the process by which viral DNA integrates into host cell DNA?

    <p>Lysogeny</p> Signup and view all the answers

    What is the result of a bacterial cell carrying a prophage?

    <p>The cell acquires new traits</p> Signup and view all the answers

    What is the purpose of attenuated viral variants in vaccines?

    <p>To retain antigenicity</p> Signup and view all the answers

    What is the result of a temperature-sensitive mutation in a virus?

    <p>The virus can only replicate at a low temperature</p> Signup and view all the answers

    What is the term used to describe the process by which viruses carry genes from one cell to another?

    <p>Transduction</p> Signup and view all the answers

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