Laboratory Diagnosis: Virus Identification in Cell Culture

What is the primary mechanism by which enveloped viruses penetrate into a cell?

Pinocytosis (viropexis)

What is the average number of progeny virions produced within hours after one virion infects a cell?

Hundreds

During what stage of viral replication are no virus particles detected within the infected cell?

Eclipse period

What is required for a virus to infect a cell?

Surface receptors specific to the virus Signup and view all the answers

What is the correct order of the steps in viral replication?

Attachment, Penetration, Transcription, Assembly, Release Signup and view all the answers

What is the term for the process by which viruses enter cells through the formation of vesicles?

Pinocytosis Signup and view all the answers

What is the primary method used to detect the presence of a virus in a patient's specimen?

Observation of cytopathic effect Signup and view all the answers

What is the purpose of an antibody-based test in virus identification?

To identify the type of virus Signup and view all the answers

What is the characteristic of Negri bodies?

They are formed in the cytoplasm of infected cells Signup and view all the answers

What is the significance of IgM in serologic procedures?

It is used to diagnose a current infection Signup and view all the answers

What is the purpose of electron microscopy in virus identification?

To identify viruses that are dangerous to grow in culture Signup and view all the answers

What is the characteristic of multinucleated giant cells?

They are formed by several viruses Signup and view all the answers

Which type of virus acquires its envelope by budding through the nuclear membrane?

Herpesviruses Signup and view all the answers

What is the term used to describe the process by which viral DNA integrates into host cell DNA?

Lysogeny Signup and view all the answers

What is the result of a bacterial cell carrying a prophage?

The cell acquires new traits Signup and view all the answers

What is the purpose of attenuated viral variants in vaccines?

To retain antigenicity Signup and view all the answers

What is the result of a temperature-sensitive mutation in a virus?

The virus can only replicate at a low temperature Signup and view all the answers

What is the term used to describe the process by which viruses carry genes from one cell to another?

Transduction Signup and view all the answers