Laboratory Diagnosis and Treatment of Meningitis
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Questions and Answers

Which of the following is NOT a risk factor for Neisseria meningitidis infection?

  • Recent viral respiratory infection
  • Close contact with an infected person
  • Breastfeeding (correct)
  • Active smoking

Which of the following statements about the outer membrane of Neisseria species is TRUE?

  • It lacks outer membrane proteins (OMPs)
  • It has a thick peptidoglycan layer
  • It is highly resistant to complement-mediated lysis
  • It contains lipopolysaccharide (LPS) with a core oligosaccharide but no O-antigen (correct)

Which of the following challenges is NOT associated with developing vaccines for Neisseria species?

  • Lack of effective animal models
  • High antigenic diversity
  • Inability to induce long-lasting immunity
  • Lack of understanding of virulence factors (correct)

How does the outer membrane of Neisseria species differ from that of Escherichia coli?

<p>Neisseria species have a different LPS structure (D)</p> Signup and view all the answers

Which of the following statements about the outer membrane of Haemophilus influenzae is TRUE?

<p>It contains lipooligosaccharide (LOS) with a core oligosaccharide (D)</p> Signup and view all the answers

What is the primary challenge in developing a universal vaccine against Neisseria meningitidis?

<p>High antigenic diversity of capsular polysaccharides (C)</p> Signup and view all the answers

Which of the following is a key difference between the outer membrane of Neisseria species and Escherichia coli?

<p>Neisseria species have a different LPS structure (A)</p> Signup and view all the answers

Which of the following is a risk factor for Neisseria gonorrhoeae infection?

<p>Multiple sexual partners (B)</p> Signup and view all the answers

Which of the following statements about the outer membrane of Neisseria species is FALSE?

<p>It has a thick peptidoglycan layer (C)</p> Signup and view all the answers

Which of the following is a challenge in developing vaccines for Neisseria gonorrhoeae?

<p>Lack of effective animal models (A)</p> Signup and view all the answers

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