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Questions and Answers
What is the trade name for Labetalol?
What is the trade name for Labetalol?
What class of medication is Labetalol?
What class of medication is Labetalol?
Nonselective beta-blocker (class II antiarrhythmic)
What is the mechanism of action (MOA) of Labetalol?
What is the mechanism of action (MOA) of Labetalol?
It lowers blood pressure by blocking beta receptors and alpha-1 receptors, causing vasodilation.
What are the indications for using Labetalol?
What are the indications for using Labetalol?
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What are the contraindications for Labetalol?
What are the contraindications for Labetalol?
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What are common side effects of Labetalol?
What are common side effects of Labetalol?
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The initial dosage for Labetalol is ______ mg via slow IV over 2 minutes.
The initial dosage for Labetalol is ______ mg via slow IV over 2 minutes.
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What is the maximum dose of Labetalol?
What is the maximum dose of Labetalol?
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Study Notes
Labetalol Overview
- Trade names: Trandate, Normodyne
- Class: Nonselective beta-blocker, categorized under class II antiarrhythmics.
Mechanism of Action (MOA)
- Functions as a potent agent for lowering blood pressure.
- Blocks beta receptors without preference and also inhibits alpha-1 receptors, resulting in vasodilation.
Clinical Indications
- Primarily used for acute management of hypertensive emergencies.
- Effective in conditions like altered mental status, chest pain, and renal failure.
Contraindications
- Not recommended for patients with asthma or chronic heart failure (CHF).
- Avoid use in individuals with heart block, bradycardia, or cardiogenic shock.
Side Effects
- Common adverse effects include bradycardia, hypotension, and lethargy.
- Other potential reactions: CHF exacerbation, dyspnea, wheezing, and general weakness.
Dosage and Administration
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First Method:
- Initial dose: 20 mg administered slowly via IV over 2 minutes.
- Check supine blood pressure immediately before and 5-10 minutes after administration.
- Subsequent dose: 40 mg every 10 minutes until target supine BP is reached.
- Maximum allowable dose is 300 mg.
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Second Method:
- Prepare a solution of 500 mg Labetalol added to 250 mL D5W.
- Administer at an infusion rate of 2 mg/min while continuously monitoring blood pressure.
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Test your knowledge on Labetalol with these flashcards! Learn about its trade names, class, mechanism of action, and indications. Perfect for pharmacology students or healthcare professionals looking to refresh their understanding.
