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Questions and Answers
What is the total volume of the final product in the first procedure?
What is the total volume of the final product in the first procedure?
- 250 ml (correct)
- 187.5 ml
- 173.75 ml
- 1000 ml
What is the weight of Calamine in the first procedure?
What is the weight of Calamine in the first procedure?
- 37.5 gm (correct)
- 75 gm
- 50 gm
- 150 gm
What is the volume of water added to the beaker in the second procedure?
What is the volume of water added to the beaker in the second procedure?
- 174 ml
- 44.5 ml (correct)
- 50 ml
- 250 ml
What is the purpose of adding liquefied phenol in the first procedure?
What is the purpose of adding liquefied phenol in the first procedure?
What is the volume of the final product in the second procedure?
What is the volume of the final product in the second procedure?
What is the purpose of adding glycerin in the first procedure?
What is the purpose of adding glycerin in the first procedure?
What is the ratio of grams of active ingredient in 100 grams of solution according to weight/weight percentage?
What is the ratio of grams of active ingredient in 100 grams of solution according to weight/weight percentage?
How many milliliters of distilled water are required to complete the volume to 50ml in the first procedure?
How many milliliters of distilled water are required to complete the volume to 50ml in the first procedure?
What is the equivalent expression of 30%?
What is the equivalent expression of 30%?
What is the volume of the active ingredient in 100ml of solution according to volume/volume percentage?
What is the volume of the active ingredient in 100ml of solution according to volume/volume percentage?
How many grams of glycerin are required to prepare 250g of 5% w/w solution?
How many grams of glycerin are required to prepare 250g of 5% w/w solution?
What is the purpose of the formula Quantity of formula desired / Quantity of formula given = F?
What is the purpose of the formula Quantity of formula desired / Quantity of formula given = F?
What is the unit of measurement for bentonite in the given prescription?
What is the unit of measurement for bentonite in the given prescription?
What is the purpose of adding amaranth solution to the mixture in the first procedure?
What is the purpose of adding amaranth solution to the mixture in the first procedure?
What is the primary characteristic of a solution in pharmaceutical preparations?
What is the primary characteristic of a solution in pharmaceutical preparations?
What is the first step in the general procedure of preparing a simple solution?
What is the first step in the general procedure of preparing a simple solution?
What percentage of the final volume of the prescription is used to subtract the volume of the liquid ingredient?
What percentage of the final volume of the prescription is used to subtract the volume of the liquid ingredient?
What is the purpose of transferring the content of the beaker to a measuring cylinder?
What is the purpose of transferring the content of the beaker to a measuring cylinder?
What is the label color for external use?
What is the label color for external use?
In Example 1, how much water is used to dissolve NaCl initially?
In Example 1, how much water is used to dissolve NaCl initially?
In Example 2, how much water remains after subtracting the volume of the coloring agent?
In Example 2, how much water remains after subtracting the volume of the coloring agent?
What is the final step in the procedure of preparing a simple solution?
What is the final step in the procedure of preparing a simple solution?
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Study Notes
Pharmaceutical Calculations
- Percent means by hundred or in a hundred, can be expressed as a ratio, common or decimal fraction.
- There are three types of percentage: Weight/Weight, Weight/Volume, and Volume/Volume.
Preparation of Simple Solutions
- General procedure:
- Weigh the solid ingredient and put it in a beaker.
- Subtract the volume of liquid ingredient from ¾ of the final volume of the prescription.
- Dissolve the solid ingredients in the remaining amount of the vehicle.
- Add the liquid ingredient.
- Convert the content of the beaker into the measuring cylinder and complete the volume up to the required amount by the addition of the vehicle.
- Transfer the content of the measuring cylinder to a wide mouth bottle and put the suitable label.
Examples of Simple Solutions
-
Example 1: NaCl 25mg, Water q.s. 200ml
- Calculate 200ml x 3/4 = 150ml of water used to dissolve NaCl initially.
- Procedure: Weigh 25mg of NaCl, dissolve in 150ml of water, and complete the volume with water to 200ml.
-
Example 2: NaCl 50mg, Coloring agent 10ml, Water q.s. 100ml
- Calculate 100ml x 3/4 = 75ml, then subtract 10ml of coloring agent to get 65ml of water used to dissolve NaCl initially.
- Procedure: Weigh 50mg of NaCl, dissolve in 65ml of water, add 10ml of coloring agent, and complete the volume with water to 100ml.
Reducing and Enlarging Formulas
- Formula: Quantity of formula desired / Quantity of formula given = F
- Multiply each ingredient by factor F to get the required quantity.
Procedure for Calamine Lotion
- Weigh each solid ingredient alone and put in a beaker.
- Measure 174ml of water and dissolve solid substances with stirring.
- Add 1.25ml of liquefied phenol and 12.5ml of glycerin to the beaker with stirring.
- Transfer to the graduated cylinder and complete the volume with water to 250ml.
- Transfer to the suitable container and label it.
Procedure for Sodium Bicarbonate Solution
- Weigh 1gm of sodium bicarbonate and put in a beaker.
- Measure 44.5ml of water and dissolve sodium bicarbonate with stirring.
- Add 0.5ml of Tr. Of cardamom to the beaker with stirring.
- Transfer to the graduated cylinder and complete the volume with water to 60ml.
- Transfer to the reagent bottle and put label.
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