Krebs Cycle - Helwan University Pharmacy

In eukaryotic cells, where does the Krebs cycle take place?

Why is it important that the Krebs cycle occurs close to the electron transport chain (ETC)?

Which of the following cell types does NOT perform the Krebs cycle?

Cancer cells often exhibit aerobic glycolysis, also known as the Warburg effect. How does this affect glucose metabolism?

What is the primary purpose of using fluorodeoxyglucose (FDG) in PET scans?

In hypoxic conditions, what metabolic pathway is favored over the Krebs cycle?

What are the net products of glycolysis?

What is the net yield of the transition step from pyruvate to acetyl CoA for each molecule of glucose?

Which two metabolic fates does citrate have after its production in the Krebs cycle?

What is the metabolic fate of alpha-ketoglutarate and oxaloacetate?

What is succinyl-CoA a precursor for?

Leucine and Lysine follow what pathway?

Which of the following is a substrate for Krebs Cycle and is essential for manufacturing oxaloacetate?

Which of the following reactions in the Krebs cycle directly produces a high-energy phosphate compound via substrate-level phosphorylation?

Which 3 steps have a negative delta G and drives the Krebs cycle?

Which of the following is considered the slowest irreversible enzyme and is also the rate limiting step?

Which of the following enzymes embedded in the IMM (inner mitochondrial membrane)?

Which of the following is considered toxic and a 'Suicide Substrate' of aconitase in Krebs Cycle?

When is energy mobilization and alternative fuel used?

When is storage and biosynthesis used?

What inhibits Citrate Synthase and Isoctrate DH in the Fed State?

What activates Isoctrate DH and a-KG DH in the Starvation State?

In the Starvation state, ___________ is/are used as primary fuel?

How many ATP are yielded by 1 NADH?

What mutation in the enzyme could cause Pheochromocytoma?

What mutation in the enzyme could cause Glioma?

What mutation in the enzyme could cause Leioma (fibroid)?

Which of the following conditions involving the Krebs cycle leads to feeling cold even in summer?

What is the central hub of metabolism, linking various catabolic and anabolic pathways?

What 2 molecules do CHO (carbohydrates) produce for in Krebs Cycle?

What molecule do Lipids produce for in Krebs Cycle?

What can OAA (oxaloacetate) be diverted to forming?

What is a-Ketoglutarate used to synthesize?

What is OAA (oxaloacetate) used to synthesize?

Which of the following Krebs cycle intermediates is exported to the cytosol for lipid biosynthesis?

Which Krebs cycle intermediate contributes to heme production?

If a hypothetical drug was created that could COMPLETELY inhibit the malate-aspartate shuttle, but allowed for normal function of the glycerol-3-phosphate shuttle, how many theoretical ATP would result from each glucose molecule metabolized?