Podcast
Questions and Answers
What is the main purpose of the Krebs Cycle?
What is the main purpose of the Krebs Cycle?
- Generate NADH for the citric acid cycle
- Convert pyruvate to lactate
- Convert glucose to energy after glycolysis (correct)
- Produce ATP directly
Where does the energy for ATP synthesis in oxidative phosphorylation come from?
Where does the energy for ATP synthesis in oxidative phosphorylation come from?
- NADH and FADH2 from glycolysis
- Formation of citric acid in the Krebs Cycle
- Conversion of glucose into pyruvate
- Protons crossing the inner mitochondrial membrane via ATPase (correct)
What is the preparatory step for the Krebs Cycle?
What is the preparatory step for the Krebs Cycle?
- Production of NADH for energy transport
- Conversion of pyruvate to lactate
- Formation of pyruvate
- Formation of Acetyl CoA (correct)
Which molecule is deficient in dietary thiamine deficiency, leading to the accumulation of pyruvate?
Which molecule is deficient in dietary thiamine deficiency, leading to the accumulation of pyruvate?
What role does NADH and FADH2 play in the electron transport chain?
What role does NADH and FADH2 play in the electron transport chain?
Where does the Krebs Cycle take place in the cell?
Where does the Krebs Cycle take place in the cell?
What is the initial compound that combines with acetyl CoA to enter the Krebs cycle?
What is the initial compound that combines with acetyl CoA to enter the Krebs cycle?
Which enzyme complex deficiency can lead to lactic acidosis similar to what is observed in alcoholics?
Which enzyme complex deficiency can lead to lactic acidosis similar to what is observed in alcoholics?
What are the main products generated from the Krebs cycle per cycle for each glucose molecule metabolized?
What are the main products generated from the Krebs cycle per cycle for each glucose molecule metabolized?
Which nutrient deficiency is commonly observed in alcoholics and contributes to the development of metabolic disturbances?
Which nutrient deficiency is commonly observed in alcoholics and contributes to the development of metabolic disturbances?
What compound is progressively oxidized through a series of enzyme-catalyzed reactions in the Krebs cycle?
What compound is progressively oxidized through a series of enzyme-catalyzed reactions in the Krebs cycle?
Which compound is NOT directly generated from the Krebs cycle per cycle?
Which compound is NOT directly generated from the Krebs cycle per cycle?
What is the role of citrate synthetase in the Krebs cycle?
What is the role of citrate synthetase in the Krebs cycle?
What is the effect of fluoroacetate on the Krebs cycle?
What is the effect of fluoroacetate on the Krebs cycle?
What is the net ATP yield from the Krebs cycle?
What is the net ATP yield from the Krebs cycle?
What is the role of oxaloacetic acid in the Krebs cycle?
What is the role of oxaloacetic acid in the Krebs cycle?
What is the result of arsenic binding to inorganic phosphate?
What is the result of arsenic binding to inorganic phosphate?
What is the current ATP yield from glycolysis and the Krebs cycle?
What is the current ATP yield from glycolysis and the Krebs cycle?
During oxidative phosphorylation, what is the total ATP yield from 10 NADH and 2 FADH2?
During oxidative phosphorylation, what is the total ATP yield from 10 NADH and 2 FADH2?
What is the primary regulator of oxidative phosphorylation?
What is the primary regulator of oxidative phosphorylation?
How many ATP molecules are generated per NADH during oxidative phosphorylation?
How many ATP molecules are generated per NADH during oxidative phosphorylation?
What is the effect of high ATP levels on citrate synthetase?
What is the effect of high ATP levels on citrate synthetase?
What is the effect of adding ADP to mitochondria?
What is the effect of adding ADP to mitochondria?
What is the role of FADH2 in oxidative phosphorylation?
What is the role of FADH2 in oxidative phosphorylation?
What is the allosteric inhibitor of citrate synthase?
What is the allosteric inhibitor of citrate synthase?
What is the primary driver of the Electron Transport Chain (ETC) and oxidative phosphorylation?
What is the primary driver of the Electron Transport Chain (ETC) and oxidative phosphorylation?
What is the byproduct of oxidative phosphorylation that drives the Electron Transport Chain?
What is the byproduct of oxidative phosphorylation that drives the Electron Transport Chain?
What is the substrate for citrate synthase in the citric acid cycle?
What is the substrate for citrate synthase in the citric acid cycle?
What is the purpose of O2 in oxidative phosphorylation?
What is the purpose of O2 in oxidative phosphorylation?
What is the effect of adding ADP to the mitochondrial reaction?
What is the effect of adding ADP to the mitochondrial reaction?
