Krebs Cycle and Cellular Respiration Quiz
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Questions and Answers

What is the net gain of ATP produced during glycolysis?

  • 3
  • 4
  • 2 (correct)
  • 5
  • Which of the following is a product of the citric acid cycle?

  • Glucose
  • ATP
  • Pyruvate
  • NADH (correct)
  • How many molecules of ATP are produced per molecule of glucose during oxidative phosphorylation?

  • 38 (correct)
  • 40
  • 32
  • 2
  • What is the role of FAD in the citric acid cycle?

    <p>It acts as an electron acceptor. (B)</p> Signup and view all the answers

    Which of the following steps in the citric acid cycle involves the addition of a water molecule?

    <p>Conversion of malate to oxaloacetate (D)</p> Signup and view all the answers

    What is the other name for the Krebs cycle?

    <p>Citric Acid Cycle (D)</p> Signup and view all the answers

    What is the main purpose of the Krebs cycle?

    <p>To generate ATP and electron carriers (A)</p> Signup and view all the answers

    What molecule combines with oxaloacetate to initiate the Krebs cycle?

    <p>Acetyl-CoA (C)</p> Signup and view all the answers

    How many ATP molecules are produced directly in the Krebs cycle per glucose molecule?

    <p>2 (B)</p> Signup and view all the answers

    What is the primary role of NADH and FADH2 in the Krebs cycle?

    <p>They provide electrons for the electron transport chain (A)</p> Signup and view all the answers

    Which process is NOT a component of the Krebs cycle?

    <p>Phosphorylation (D)</p> Signup and view all the answers

    What is the name of the process that converts pyruvate to acetyl-CoA?

    <p>Link reaction (B)</p> Signup and view all the answers

    What is the significance of the Krebs cycle in anabolism?

    <p>It provides building blocks for biosynthesis (D)</p> Signup and view all the answers

    What is the net gain of ATP produced during the Krebs cycle per glucose molecule?

    <p>2 (A)</p> Signup and view all the answers

    How many NADH molecules are produced altogether per glucose molecule in the Krebs cycle?

    <p>6 (C)</p> Signup and view all the answers

    What happens to Isocitrate during its conversion to α-Ketoglutarate?

    <p>It loses a CO2 molecule and reduces NAD+ to NADH. (B)</p> Signup and view all the answers

    Which enzyme is responsible for the conversion of Isocitrate to α-Ketoglutarate?

    <p>Isocitrate dehydrogenase (D)</p> Signup and view all the answers

    What is produced as a result of the oxidation of Isocitrate?

    <p>NADH (C)</p> Signup and view all the answers

    During the conversion of α-Ketoglutarate, what occurs after another CO2 molecule is lost?

    <p>It is oxidized, reducing NAD+ to NADH. (B)</p> Signup and view all the answers

    What type of reaction occurs when Citric acid loses its CH2 and CO2 molecules?

    <p>Decarboxylation (D)</p> Signup and view all the answers

    What is the initial product formed from citrate during the conversion process?

    <p>Isocitrate (A)</p> Signup and view all the answers

    Which enzyme is responsible for converting citrate to isocitrate?

    <p>Aconitase (B)</p> Signup and view all the answers

    What process occurs when proteins are broken down into amino acids during severe starvation?

    <p>Deamination (D)</p> Signup and view all the answers

    What happens to isocitrate during its conversion in the citric acid cycle?

    <p>It loses CO2 (C)</p> Signup and view all the answers

    Which compound is formed after isocitrate loses a CO2 molecule?

    <p>α-Ketoglutarate (C)</p> Signup and view all the answers

    Which type of organism can perform both aerobic respiration and anaerobic respiration?

    <p>Facultative anaerobes (C)</p> Signup and view all the answers

    What is the end product of alcoholic fermentation carried out by yeast?

    <p>Ethanol (D)</p> Signup and view all the answers

    During the conversion of isocitrate, what does NAD+ get reduced to?

    <p>NADH (A)</p> Signup and view all the answers

    What role does aconitase play in the citric acid cycle?

    <p>It catalyzes the conversion from citrate to isocitrate (B)</p> Signup and view all the answers

    During strenuous exercise, what causes muscle cells to switch from aerobic respiration to lactic acid fermentation?

    <p>Reduced oxygen supply (B)</p> Signup and view all the answers

    What accumulates in muscles during lactic acid fermentation?

    <p>Lactate (B)</p> Signup and view all the answers

    What type of reaction occurs when citrate is converted to isocitrate?

    <p>Isomerization (C)</p> Signup and view all the answers

    What is the significance of the CO2 molecule lost during the conversion of isocitrate?

    <p>It indicates an irreversible reaction (C)</p> Signup and view all the answers

    What is the role of NADH in alcoholic fermentation?

    <p>It reduces ethanal to ethanol. (C)</p> Signup and view all the answers

    What is the primary function of lactate in muscle cells during exercise?

    <p>To enhance muscle performance (C)</p> Signup and view all the answers

    Where is excess lactate transported after accumulation in muscles?

    <p>To the liver (D)</p> Signup and view all the answers

    What is the total number of ATP produced from 10 NADH and 2 FADH2 during aerobic respiration?

    <p>38 ATP (A)</p> Signup and view all the answers

    Which factor affects the variation in ATP production in different cells?

    <p>The type of shuttle used for electron transport (C)</p> Signup and view all the answers

    What is the final equation representing the overall reaction of aerobic respiration?

    <p>C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + 38 ATP (B)</p> Signup and view all the answers

    How many ATP molecules are generated from 1 FADH2 during aerobic respiration?

    <p>2 ATP (C)</p> Signup and view all the answers

    In brain cells, how many ATP result from NADH during glycolysis?

    <p>2 ATP (B)</p> Signup and view all the answers

    What is the amount of ATP produced during glycolysis?

    <p>2 ATP (B)</p> Signup and view all the answers

    What is produced by the oxidation of fats in respiration?

    <p>Glycerol and acetyl CoA (B)</p> Signup and view all the answers

    During oxidative phosphorylation, how much ATP is produced on average per glucose molecule?

    <p>32 to 34 ATP (C)</p> Signup and view all the answers

    Which substrate is primarily oxidized for energy during aerobic respiration?

    <p>Carbohydrates (B)</p> Signup and view all the answers

    Which of the following statements about ATP yield in aerobic respiration is false?

    <p>All cells produce the same amount of ATP. (A)</p> Signup and view all the answers

    Flashcards

    Citric Acid Cycle

    A key metabolic pathway involved in cellular respiration, converting acetyl CoA into energy.

    Acetyl CoA

    A molecule that enters the citric acid cycle, derived from carbohydrates and fats.

    NADH

    An electron carrier produced during glycolysis and the citric acid cycle, important for ATP production.

    ATP Production

    The generation of adenosine triphosphate (ATP) through metabolic pathways.

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    Oxidative Phosphorylation

    The metabolic pathway where ATP is formed as electrons are transferred to oxygen.

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    Deamination

    The removal of amino groups from amino acids during protein hydrolysis.

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    Facultative anaerobes

    Organisms that can respire both aerobically and anaerobically depending on oxygen availability.

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    Obligate anaerobes

    Organisms that can only survive in low or no oxygen and rely solely on anaerobic respiration.

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    Alcoholic fermentation

    A process by which yeast converts pyruvate into ethanol and CO2, regenerating NAD+.

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    Lactic acid fermentation

    A process that converts pyruvate into lactate in muscle cells when oxygen is scarce.

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    Pyruvate

    A key intermediate in metabolism, converted to lactate or ethanol depending on the fermentation type.

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    Liver role in lactate

    The liver converts lactate back to pyruvate if oxygen is available, allowing aerobic respiration.

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    NAD+ regeneration

    The process in fermentation where NAD+ is regenerated for re-use, allowing continued ATP production.

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    Citrate

    A compound formed in the citric acid cycle and the first input molecule.

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    Isocitrate

    The isomer of citrate formed by removal of water and addition of another molecule.

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    Aconitase

    An enzyme that catalyzes the conversion of citrate to isocitrate.

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    α-Ketoglutarate

    The compound formed from isocitrate after losing a CO2 molecule.

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    CO2 loss

    The process in which isocitrate loses a carbon dioxide molecule during conversion to α-ketoglutarate.

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    Oxidation of Isocitrate

    The process by which isocitrate loses electrons, reducing NAD+ to NADH.

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    Isocitrate Dehydrogenase

    An enzyme that catalyzes the conversion of isocitrate to α-ketoglutarate.

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    Cellular Respiration

    The process by which cells convert glucose and oxygen into energy, carbon dioxide, and water.

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    Glycolysis

    The first stage of cellular respiration where glucose is broken down into pyruvate, yielding ATP and NADH.

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    Krebs Cycle (Citric Acid Cycle)

    A series of enzyme-catalyzed reactions that produce energy carriers (NADH, FADH2) from acetyl CoA.

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    Products of Krebs Cycle

    For each glucose, the Krebs cycle produces 2 ATP, 6 NADH, and 2 FADH2.

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    Electron Transport Chain

    The final stage of cellular respiration where NADH and FADH2 are used to produce ATP through oxidative phosphorylation.

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    Decarboxylation

    The removal of carbon dioxide from a molecule, occurring in the Krebs cycle.

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    Anabolism

    The aspect of metabolism that involves building larger molecules from smaller ones, contributing to cellular functions.

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    Fermentation

    An anaerobic process that allows cells to generate energy without oxygen, producing lactic acid or alcohol.

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    NADH ATP yield

    1 NADH can generate 3 ATP in aerobic respiration.

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    FADH2 ATP yield

    1 FADH2 can generate 2 ATP in aerobic respiration.

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    ATP total from glycolysis

    Glycolysis produces 2 ATP per glucose molecule.

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    ATP total from Krebs cycle

    Krebs cycle also produces 2 ATP per glucose molecule.

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    Total ATP from ETC

    Electron Transport Chain generates 30 ATP from 10 NADH and 4 ATP from 2 FADH2.

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    Overall ATP yield

    Total ATP produced in aerobic respiration is 38 ATP per glucose molecule.

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    Equation of aerobic respiration

    C6H12O6 + 6O2 → 6CO2 + 6H2O + 38 ATP.

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    Effect of shuttle systems

    Electrons from glycolysis can be shuttled to either FAD or NAD+, affecting ATP yield.

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    ATPs from brain cells

    Brain cells yield 36 ATP due to FAD shuttle use.

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    ATPs from liver and heart cells

    Liver and heart cells yield 38 ATP as they utilize NAD+ shuttle.

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