SKELETAL LEVEL OF ORGANIZATION

Why are older individuals encouraged to lift weights to help their bones and reduce the effects of osteoporosis? = bones respond to and get stronger with force In osteogenesis imperfecta, which molecule is altered? = COLLAGEN What is not an inorganic component of bone? = COLLAGEN How are the organic and inorganic components of bone integrated? = Hydroxyapatite nanocrystals integrate with collagen fibers

Which cells transform within the bone? = osteoblasts become osteocytes Why do we splint a bone after a fracture? = To minimize movement Hydroxyapatite = an inorganic mixture containing calcium and phosphate Which cells secrete osteoid? = OSTEOBLASTS

A main role of proteoglycans in bone is to: = attract water that acts to cushion compression Which nanostructure is responsible for compression resistance in cartilage? = PROTEOGLYCANS Which is not part of mature bone? = PROTEOGLYCANS Which is not part of mature cartilage? = blood vessels

What feature of the hydroxyapatite crystals allow them to easily exchange ions? = They are nano sized with a large surface area Which cells are osteoporosis drugs intended to inhibit? = OSTEOCLASTS How is water integrated into cartilage? = A network of negatively charged glycosylated proteins attract water. Which nanostructure is responsible for tensile resistance in bone? = COLLAGEN

For which type of fracture would serious reconstructive measures be needed? = COMMINUTED FRACTURE Which classification of bone has a collection of specialized cells, organic extracellular matrix proteins, and inorganic salt crystals? = BOTH = COMPACT BONE = SPONGY BONE