④ Genetics (hard MCQ)

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Questions and Answers

During transcription, what role does RNA polymerase play?

  • It initiates DNA replication by adding primers to the template strand.
  • It unwinds the DNA double helix and synthesizes a complementary mRNA strand. (correct)
  • It catalyzes the formation of peptide bonds between amino acids.
  • It transports amino acids to the ribosome for protein synthesis.

Which statement accurately describes the function of ribosomes in translation?

  • Ribosomes synthesize proteins by reading mRNA codons and assembling amino acids. (correct)
  • Ribosomes modify and fold proteins.
  • Ribosomes replicate DNA during cell division.
  • Ribosomes transcribe DNA into mRNA.

A mutation in a gene results in a non-functional protein. Which type of mutation is LEAST likely to cause this outcome?

  • Missense mutation in the active site of the enzyme.
  • Nonsense mutation early in the gene.
  • Frameshift mutation near the start codon.
  • Silent mutation. (correct)

Which of the following is an epigenetic mechanism that can alter gene expression without changing the DNA sequence itself?

<p>DNA methylation. (C)</p> Signup and view all the answers

What is the primary role of tRNA in the process of translation?

<p>To transport amino acids to the ribosome and match them to the corresponding mRNA codon. (A)</p> Signup and view all the answers

A certain protein is normally produced in liver cells but is absent in brain cells. Which mechanism is MOST likely responsible for this tissue-specific expression?

<p>Specific transcription factors are present in liver cells but not in brain cells. (B)</p> Signup and view all the answers

Which of the following events occurs during the termination stage of translation?

<p>The ribosome reaches a stop codon on the mRNA, and a release factor binds to the ribosome. (B)</p> Signup and view all the answers

A researcher observes that a particular gene is heavily methylated in cancer cells, leading to reduced expression. Which of the following is a likely consequence of this methylation?

<p>Inhibition of transcription. (C)</p> Signup and view all the answers

If a cell has a mutation that disables its ability to properly proofread and correct errors during DNA replication, what is the MOST likely consequence?

<p>A higher rate of mutation. (B)</p> Signup and view all the answers

Which of the following BEST describes the role of the promoter region in transcription?

<p>It is the site where RNA polymerase binds to initiate transcription. (A)</p> Signup and view all the answers

A mutation occurs in a gene that codes for a protein involved in DNA repair. What is the MOST likely outcome of this mutation?

<p>Increased susceptibility to mutations. (C)</p> Signup and view all the answers

How do epigenetic modifications contribute to cellular differentiation in multicellular organisms?

<p>By selectively activating or inactivating genes, leading to different patterns of gene expression. (C)</p> Signup and view all the answers

Which of the following is a characteristic of a frameshift mutation?

<p>It shifts the reading frame of the genetic code, leading to a completely different amino acid sequence downstream of the mutation. (C)</p> Signup and view all the answers

How does the process of transcription differ in prokaryotes compared to eukaryotes?

<p>In prokaryotes, transcription and translation can occur simultaneously in the cytoplasm, while in eukaryotes, transcription occurs in the nucleus, and translation occurs in the cytoplasm. (A)</p> Signup and view all the answers

A particular mRNA molecule has the sequence 5'-AUG-CAU-GAC-UAA-3'. How many amino acids will be in the resulting polypeptide?

<p>3 (A)</p> Signup and view all the answers

Which of the following is NOT a typical mechanism of epigenetic regulation?

<p>mRNA splicing. (A)</p> Signup and view all the answers

In what way does alternative splicing increase protein diversity?

<p>By allowing different combinations of exons to be included in the final mRNA. (C)</p> Signup and view all the answers

What is the role of aminoacyl-tRNA synthetases in translation?

<p>They ensure that each tRNA molecule is bound to its correct amino acid. (C)</p> Signup and view all the answers

Which of the following is a characteristic of enhancers in eukaryotic gene regulation?

<p>They can be located far upstream or downstream from the gene they regulate and increase the rate of transcription. (A)</p> Signup and view all the answers

A protein is produced in a misfolded state. Which cellular structure is primarily responsible for degrading this misfolded protein?

<p>Proteasome. (D)</p> Signup and view all the answers

Flashcards

Transcription

The synthesis of RNA from a DNA template.

Translation

The synthesis of a polypeptide (protein) from mRNA.

Mutation

A change in the nucleotide sequence of DNA.

Epigenetics

Modifications to DNA that affect gene expression without altering the nucleotide sequence.

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Study Notes

  • BioNinja provides resources for IB Biology, covering course information, topics, themes, and review materials.
  • The course includes a syllabus outline, command terms, reporting skills, and practical work guidance.
  • Key topics covered are Biomolecules, Cells, Metabolism, Genetics, Heredity, Equilibrium, Body Systems, Plant Systems, Biodiversity, Nutrition, Ecology, and Human Impacts.
  • Themes explored are Unity and Diversity, Form and Function, Interdependencies, and Continuity/Change.
  • Review resources include PowerPoints, topic notes, summaries, and worksheets.
  • Standard Level (SL) and Higher Level (HL) content is available.

Genetics

  • Resources are available for the study of Genetics.

Transcription

  • Information on Transcription is available.

Translation

  • Translation information can be found in the resources.

Mutation

  • Mutation information can be found in the resources.

Transcription

  • Transcription information can be found in the resources for higher level students.

Translation

  • Translation information can be found in the resources for higher level students.

Epigenetics

  • Epigenetics information can be found in the resources.

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