13 Questions
Which marker is specific for cholestasis in liver disease?
Bilirubin
Which marker is sensitive but not specific for hepatocellular damage in chronic liver disease?
Amino transferases (AsT & AlT)
Which marker is used to assess liver synthetic function in chronic liver disease?
Albumin
Which protein is bilirubin almost totally bound to in plasma?
Albumin
Where is bilirubin conjugated to form mono- and diglucuronides?
Liver cells
What are the main functional constituents of bile?
Bile salts
Which compound is formed when bilirubin conjugates are attacked by bacteria in the terminal ileum and colon?
Stercobilinogen
Where are most of the stercobilinogen compounds excreted?
Faeces
Which marker is a more sensitive index of hepatic transport function than total bilirubin measurements?
Bile salts
What happens to serum bilirubin concentrations when the biliary tract becomes blocked?
They rise
What happens to a patient when serum bilirubin concentrations rise due to biliary tract blockage?
They become jaundiced
Which tetrapyrrole compounds are found in urine and known as urobilinogen?
Conjugated bilirubin
What is the enterohepatic circulation?
The circulation of bile from the liver to the small intestine
Test your knowledge on types of liver disease and their markers! Learn about biliary tree (cholestasis), hepatocellular, and chronic liver diseases, and the specific markers associated with each. From bilirubin to prothrombin time, challenge yourself with this quiz on liver disease markers.
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