Know Your Liver
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Questions and Answers

Which marker is specific for cholestasis in liver disease?

  • Amino transferases (AsT & AlT)
  • Bilirubin (correct)
  • Alkaline phosphatase (ALP)
  • Gamma-glutamyltransferase (GGT)
  • Which marker is sensitive but not specific for hepatocellular damage in chronic liver disease?

  • Bilirubin
  • Gamma-glutamyltransferase (GGT)
  • Alkaline phosphatase (ALP)
  • Amino transferases (AsT & AlT) (correct)
  • Which marker is used to assess liver synthetic function in chronic liver disease?

  • Prothrombin time
  • Bilirubin
  • Albumin (correct)
  • Alkaline phosphatase (ALP)
  • Which protein is bilirubin almost totally bound to in plasma?

    <p>Albumin</p> Signup and view all the answers

    Where is bilirubin conjugated to form mono- and diglucuronides?

    <p>Liver cells</p> Signup and view all the answers

    What are the main functional constituents of bile?

    <p>Bile salts</p> Signup and view all the answers

    Which compound is formed when bilirubin conjugates are attacked by bacteria in the terminal ileum and colon?

    <p>Stercobilinogen</p> Signup and view all the answers

    Where are most of the stercobilinogen compounds excreted?

    <p>Faeces</p> Signup and view all the answers

    Which marker is a more sensitive index of hepatic transport function than total bilirubin measurements?

    <p>Bile salts</p> Signup and view all the answers

    What happens to serum bilirubin concentrations when the biliary tract becomes blocked?

    <p>They rise</p> Signup and view all the answers

    What happens to a patient when serum bilirubin concentrations rise due to biliary tract blockage?

    <p>They become jaundiced</p> Signup and view all the answers

    Which tetrapyrrole compounds are found in urine and known as urobilinogen?

    <p>Conjugated bilirubin</p> Signup and view all the answers

    What is the enterohepatic circulation?

    <p>The circulation of bile from the liver to the small intestine</p> Signup and view all the answers

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