Know Your Liver
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Questions and Answers

Which marker is specific for cholestasis in liver disease?

  • Amino transferases (AsT & AlT)
  • Bilirubin (correct)
  • Alkaline phosphatase (ALP)
  • Gamma-glutamyltransferase (GGT)

Which marker is sensitive but not specific for hepatocellular damage in chronic liver disease?

  • Bilirubin
  • Gamma-glutamyltransferase (GGT)
  • Alkaline phosphatase (ALP)
  • Amino transferases (AsT & AlT) (correct)

Which marker is used to assess liver synthetic function in chronic liver disease?

  • Prothrombin time
  • Bilirubin
  • Albumin (correct)
  • Alkaline phosphatase (ALP)

Which protein is bilirubin almost totally bound to in plasma?

<p>Albumin (A)</p> Signup and view all the answers

Where is bilirubin conjugated to form mono- and diglucuronides?

<p>Liver cells (C)</p> Signup and view all the answers

What are the main functional constituents of bile?

<p>Bile salts (B)</p> Signup and view all the answers

Which compound is formed when bilirubin conjugates are attacked by bacteria in the terminal ileum and colon?

<p>Stercobilinogen (B)</p> Signup and view all the answers

Where are most of the stercobilinogen compounds excreted?

<p>Faeces (B)</p> Signup and view all the answers

Which marker is a more sensitive index of hepatic transport function than total bilirubin measurements?

<p>Bile salts (B)</p> Signup and view all the answers

What happens to serum bilirubin concentrations when the biliary tract becomes blocked?

<p>They rise (B)</p> Signup and view all the answers

What happens to a patient when serum bilirubin concentrations rise due to biliary tract blockage?

<p>They become jaundiced (D)</p> Signup and view all the answers

Which tetrapyrrole compounds are found in urine and known as urobilinogen?

<p>Conjugated bilirubin (C)</p> Signup and view all the answers

What is the enterohepatic circulation?

<p>The circulation of bile from the liver to the small intestine (C)</p> Signup and view all the answers

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