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Questions and Answers
What determines the membrane permeability of drug substances?
What determines the membrane permeability of drug substances?
- Compound size (correct)
- Bioavailability
- Chemical formula
- Physical appearance
What is the characteristic of amorphous solid forms?
What is the characteristic of amorphous solid forms?
- Repetition in three-dimensional lattice units
- Definite melting points
- Long-range order
- Random molecular arrangement (correct)
Which type of solid form involves molecules or atoms arranged in repetition in a three-dimensional lattice?
Which type of solid form involves molecules or atoms arranged in repetition in a three-dimensional lattice?
- Crystalline (correct)
- Solvates
- Polymeric
- Cocrystals
What is the defining characteristic of polymorphism in drug formulation?
What is the defining characteristic of polymorphism in drug formulation?
What is a prodrug in relation to drug transformation?
What is a prodrug in relation to drug transformation?
Which type of solid form can accommodate other molecules to form salts?
Which type of solid form can accommodate other molecules to form salts?
What is the primary function of excipients in drug formulations?
What is the primary function of excipients in drug formulations?
Which of the following excipients is commonly used as a thickening agent or to form topical gels?
Which of the following excipients is commonly used as a thickening agent or to form topical gels?
What was the issue observed with the delavirdine mesylate tablets when exposed to high relative humidity?
What was the issue observed with the delavirdine mesylate tablets when exposed to high relative humidity?
Which of the following is a physicochemical property used to test chemical substances?
Which of the following is a physicochemical property used to test chemical substances?
What is the phenomenon of melting point depression?
What is the phenomenon of melting point depression?
Which of the following statements about vapor pressure is true?
Which of the following statements about vapor pressure is true?
What is the definition of a dosage form?
What is the definition of a dosage form?
What is required before a new drug can be distributed and used?
What is required before a new drug can be distributed and used?
What did the Durham-Humphrey Amendment of 1951 establish?
What did the Durham-Humphrey Amendment of 1951 establish?
Which of the following is NOT one of the major federal enactments related to drug regulation and control?
Which of the following is NOT one of the major federal enactments related to drug regulation and control?
What is the purpose of the Investigational New Drug (IND) application?
What is the purpose of the Investigational New Drug (IND) application?
What is the definition of a dosage regimen?
What is the definition of a dosage regimen?
What is the main purpose of the Kefauver-Harris Amendments of 1962?
What is the main purpose of the Kefauver-Harris Amendments of 1962?
What did the Comprehensive Drug Abuse Prevention and Control Act of 1970 establish?
What did the Comprehensive Drug Abuse Prevention and Control Act of 1970 establish?
What are some characteristics of a goal drug according to the text?
What are some characteristics of a goal drug according to the text?
What does cGMP stand for in relation to pharmaceuticals?
What does cGMP stand for in relation to pharmaceuticals?
What does cGMP regulate in the pharmaceutical industry?
What does cGMP regulate in the pharmaceutical industry?
What is the role of USP/NF as mentioned in the text?
What is the role of USP/NF as mentioned in the text?
Which of the following is an advantage of transdermal drug delivery?
Which of the following is an advantage of transdermal drug delivery?
Which of the following is a disadvantage of transdermal drug delivery?
Which of the following is a disadvantage of transdermal drug delivery?
What is the primary reason transdermal drug delivery can improve bioavailability?
What is the primary reason transdermal drug delivery can improve bioavailability?
Which characteristic is most important for a drug to be suitable for traditional transdermal delivery?
Which characteristic is most important for a drug to be suitable for traditional transdermal delivery?
Which of the following is NOT a characteristic of drugs suitable for traditional transdermal delivery?
Which of the following is NOT a characteristic of drugs suitable for traditional transdermal delivery?
What is the primary benefit of the controlled and sustained release profile provided by transdermal drug delivery?
What is the primary benefit of the controlled and sustained release profile provided by transdermal drug delivery?
