Kidney Structure and Function Quiz
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Questions and Answers

What is the primary function of the juxtaglomerular apparatus?

  • To secrete hormone renin and regulate filtration rate (correct)
  • To produce erythropoietin for red blood cell production
  • To reabsorb electrolytes and maintain acid-base balance
  • To filter blood and control blood pressure
  • Which of the following nephrons is primarily involved in concentrating urine?

  • Midcortical nephrons
  • Cortical nephrons
  • Juxtamedullary nephrons (correct)
  • Subcortical nephrons
  • What is the percentage of filtrate that is typically reabsorbed back into the bloodstream?

  • 99% (correct)
  • 100%
  • 90%
  • 75%
  • Which hormone is responsible for regulating sodium balance and blood pressure in the body?

    <p>Aldosterone (A)</p> Signup and view all the answers

    What does a normal glomerular filtration rate (GFR) signify in kidney function?

    <p>The kidneys are filtering plasma adequately (A)</p> Signup and view all the answers

    Which type of kidney stone is most commonly formed due to hypercalcemia?

    <p>Calcium oxalate stones (C)</p> Signup and view all the answers

    What treatment is not typically recommended for managing kidney stones?

    <p>Improving oxygenation through hyperbaric therapy (C)</p> Signup and view all the answers

    Which of the following is a risk factor for developing renal cell carcinoma?

    <p>Cigarette smoking (D)</p> Signup and view all the answers

    What common symptom is associated with bladder tumors?

    <p>Painless hematuria (A)</p> Signup and view all the answers

    Which method is utilized for the surgical removal of kidney stones?

    <p>Ureteroscopy (D)</p> Signup and view all the answers

    What factor does NOT generally contribute to the formation of kidney stones?

    <p>Consuming high amounts of protein (B)</p> Signup and view all the answers

    In the context of glomerular disorders, what is glomerulonephritis primarily caused by?

    <p>Inflammation of the glomerulus (B)</p> Signup and view all the answers

    Which geographical location factor does NOT commonly influence kidney stone prevalence?

    <p>Coastal regions (A)</p> Signup and view all the answers

    What is the primary factor determining whether a stone can pass through the urinary system?

    <p>The size of the stone (A)</p> Signup and view all the answers

    What physiological response occurs in the kidney following an obstruction?

    <p>Compensatory hypertrophy and hyperfunction (C)</p> Signup and view all the answers

    What condition can arise from postobstructive diuresis?

    <p>Nephrogenic diabetes insipidus (A)</p> Signup and view all the answers

    Which of the following is a characteristic of neurogenic bladder dysfunction?

    <p>Loss of coordinated neuromuscular contraction (A)</p> Signup and view all the answers

    Which of the following describes overactive bladder syndrome (OBS)?

    <p>Sudden urge to urinate with difficulty in controlling it (C)</p> Signup and view all the answers

    What is the most common cause of urinary tract infections (UTIs)?

    <p>Bacteria from gut flora (C)</p> Signup and view all the answers

    Which type of urinary tract infection is characterized by inflammation of the bladder?

    <p>Acute cystitis (C)</p> Signup and view all the answers

    What condition results from the presence of tumors in the kidneys?

    <p>Benign or malignant growths (C)</p> Signup and view all the answers

    Which factor is not typically associated with causing lower urinary tract obstruction?

    <p>Kidney stones (A)</p> Signup and view all the answers

    How does compensatory hypertrophy affect nephron function after obstruction?

    <p>Enhances function of remaining nephrons (B)</p> Signup and view all the answers

    Which mineral is most commonly associated with the formation of calcium kidney stones?

    <p>Calcium (C)</p> Signup and view all the answers

    What is the potential consequence of prolonged upper urinary tract obstruction on kidney structures?

    <p>Tubulointerstitial fibrosis (B)</p> Signup and view all the answers

    Which of the following conditions is largely characterized by involuntary loss of urine due to nerve impairment?

    <p>Neurogenic bladder dysfunction (A)</p> Signup and view all the answers

    What type of urinary tract infection is caused by bacteria entering the urinary tract via the bloodstream?

    <p>Urosepsis (C)</p> Signup and view all the answers

    Which factor contributes to the increased risk of renal tumors?

    <p>Smoking (C)</p> Signup and view all the answers

    Which classification of kidney stones is primarily associated with infections?

    <p>Struvite stones (B)</p> Signup and view all the answers

    Which of these outcomes is most likely if upper urinary tract obstruction is resolved quickly?

    <p>Immediate restoration of kidney function (C)</p> Signup and view all the answers

    Which factor does NOT contribute to the severity of urinary tract obstruction?

    <p>Age of the patient (D)</p> Signup and view all the answers

    What is the primary waste product that forms urine in the kidneys?

    <p>Urea (B)</p> Signup and view all the answers

    Which condition is characterized by the dilation of both the ureter and the renal pelvis?

    <p>Ureterohydronephrosis (A)</p> Signup and view all the answers

    Flashcards

    Renal Cell Carcinoma (RCC)

    A type of kidney cancer.

    Kidney Stones

    Crystals or other substances that form in the urinary tract and can block it.

    Renal Calculi

    Another name for kidney stones.

    Supersaturation

    When a substance is in a higher concentration than the solvent can dissolve.

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    Glomerulonephritis

    Inflammation of the kidney's filtering system.

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    Kidney stone Risk factors

    Factors that increase the chance of getting kidney stones. Gender, age, race, location, diet, etc.

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    Renal Colic

    Pain caused by a blocked urinary tract by a kidney stone.

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    Transitional Cell Carcinoma

    Common type of bladder cancer.

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    Upper Urinary Tract Obstruction

    Blockage in the upper parts of the urinary system, often impacting kidney function.

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    Postobstructive Diuresis

    Large urine production after an obstruction is relieved.

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    Neurogenic Bladder

    Urinary problems due to nervous system issues, affecting bladder control.

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    Detrusor Hyper-reflexia

    Overactive bladder, causing frequent urination.

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    Overactive Bladder Syndrome(OBS)

    Condition causing frequent and sudden urge to urinate.

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    Urinary Tract Infection (UTI)

    Inflammation of the urinary system due to bacteria.

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    Acute Cystitis

    Inflammation of the bladder.

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    Renal Tumors

    Tumors in the kidney, possibly benign or malignant.

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    Urethral Stricture

    Narrowing of the urethra, causing urinary problems.

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    Prostate Enlargement

    Increased size of the prostate gland, affecting urination.

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    What is the functional unit of the kidney?

    The nephron is the smallest structure in the kidney responsible for filtering waste, regulating electrolytes, and maintaining fluid balance.

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    What does the glomerulus do?

    The glomerulus filters plasma, the fluid component of blood. It's like a sieve, separating waste products from the blood.

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    What is Glomerular Filtration Rate (GFR)?

    GFR measures how much plasma is filtered by the glomeruli per minute. It indicates how well the kidneys are working.

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    What happens to the filtrate after leaving the glomerulus?

    The filtrate enters the proximal convoluted tubule (PCT) where reabsorption and secretion processes begin.

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    What are the main functions of the kidney?

    The kidneys filter waste, regulate blood pressure, produce hormones, maintain electrolyte balance, and regulate acid-base balance.

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    Nephron decrease in number

    The number of nephrons decreases with age and due to renal vascular and perfusion changes.

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    GFR decline

    Glomerular Filtration Rate (GFR) decreases as people age, due to a decrease in functioning nephrons.

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    Urinary Tract

    A system for removing urine, composed of kidneys, ureters, bladder, and urethra.

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    Urinary Tract Obstruction

    Interference with urine flow along the urinary tract, due to anatomical or functional issues.

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    Hydroureter

    Urine buildup in the ureter.

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    Hydronephrosis

    Enlarged renal pelvis and calyces (cup-like structures in the kidney).

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    Ureterohydronephrosis

    Dilation of both the ureter and the pelvicaliceal system.

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    Obstruction Severity

    Depends on location, completeness, extent of ureter and kidney involvement, duration, and cause of blockage.

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    Delayed acid-base response in children

    Children process changes in body acidity more slowly than adults.

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    Study Notes

    Kidney Structure

    • Each kidney contains approximately 1.2 million nephrons
    • The nephron is the functional unit of the kidney
    • Nephrons filter plasma, reabsorb and secrete, and regulate filtrate
    • There are three types of nephrons: cortical, midcortical, and juxtamedullary.

    Glomerulus

    • The glomerulus is a network of capillaries within the nephron
    • It filters plasma, the liquid component of blood, creating a filtrate
    • The glomerular filtration rate (GFR) measures the plasma filtered per unit of time (90-120 mL/min)
    • The glomerular membrane is permeable to water but not large molecules like albumin

    Urine Formation

    • Glomerular filtration produces a protein-free filtrate
    • About 99% of the filtrate is reabsorbed into the bloodstream
    • The remaining 1% is excreted as urine.
    • Kidneys produce hormones, including renin, angiotensin, aldosterone, natriuretic peptides, and urodilantin

    Renal Function

    • Filtering waste products from the blood
    • Regulating blood pressure
    • Producing hormones
    • Maintaining electrolyte and acid-base balance
    • The nephron filters blood into a filtrate in the glomerulus
    • Waste products are secreted into filtrate, and useful products are reabsorbed
    • The filtrate is modified in the tubule by reabsorption and secretion

    Renal Function: Hormones

    • Renin-angiotensin-aldosterone system (RAAS): Regulates blood pressure
    • Erythropoietin: Stimulates red blood cell production
    • Vitamin D: Aids in calcium absorption

    Renal Function: Acid-Base Balance

    • Kidneys regulate body's acid-base balance by excreting hydrogen ions and reabsorbing bicarbonate ions.

    Renal Tests

    • Tests assess kidney function: Blood tests (e.g., creatinine, BUN), urinalysis, and clearance tests (e.g., creatinine clearance)

    Urinary Tract

    • The urinary tract consists of the kidneys, ureters, bladder, and urethra
    • Urine is made in the kidneys, travels down the ureters to the bladder, and exits the body through the urethra.
    • Obstructions in the urinary tract can affect its function

    Upper Urinary Tract Obstruction

    • Hydroureter: Accumulation of urine in the ureter
    • Hydronephrosis: Enlargement of the renal pelvis and calyces
    • Ureterohydronephrosis: Dilation of both the ureter and the pelvicaliceal system
    • Increased pressure in the glomerulus can lead to decreased kidney function and filtration

    Lower Urinary Tract Obstruction

    • Neurogenic bladder: Dysfunction of the urinary bladder due to nerve issues.
    • Overactive bladder
    • Underactive bladder
    • Can result from various conditions like urethral strictures, enlarged prostate, or pelvic organ prolapse

    Urinary Tract Infection (UTI)

    • Inflammation of the urinary tract caused by bacteria (e.g., Escherichia coli).
    • Types include acute cystitis (inflammation of the bladder), painful bladder syndrome/interstitial cystitis, and acute/chronic pyelonephritis (inflammation of the kidney and renal pelvis).

    Kidney Stones

    • Formed when salts in urine become supersaturated
    • Factors such as gender, geographic location, diet and fluid intake influence risk
    • Classified by the minerals that make up the stone

    Glomerular Disorders

    • Glomerulonephritis: Inflammation of the glomerulus
    • Causes include immune responses, infections, medications, and other conditions.
    • Symptoms include hematuria, proteinuria, oliguria, hypertension, and edema.
    • Nephrotic syndrome: Characterized by excessive protein in urine (greater than 3.5g/day)

    Chronic Kidney Disease (CKD)

    • Progressive loss of renal function, typically affecting multiple organ systems
    • Classified into five stages based on GFR (glomerular filtration rate)
    • Common causes include hypertension, diabetes, and systemic lupus erythematosus
    • Impacts fluid and electrolyte balance, calcium, phosphate, and bone metabolism, and can cause anemia

    Acute Kidney Injury (AKI)

    • Sudden decline in kidney function with decreased GFR and urine output
    • Results from ischemia, toxic injury, or sepsis.
    • Common causes include prerenal (reduced blood flow), intrarenal (damage to the kidney itself), and postrenal (obstruction of urine flow) causes

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    Description

    This quiz explores the intricate structure and function of the kidneys, focusing on nephrons, glomeruli, and urine formation. Test your understanding of how kidneys filter blood and regulate various physiological processes. Delve into the specifics of renal function and the importance of different nephron types.

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