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Ketosis and Keto Diet lec 3

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6 Questions

Which condition is necessary for the occurrence of nonpathological forms of ketosis?

High-fat and low-carbohydrate feeding

How does the ketogenic diet avoid developing into ketoacidosis?

By balancing low carbohydrate, moderate protein, and high fat

What triggers the increase in glucagon secretion in a ketogenic diet?

Hypoglycemia

Which of the following is a primary mechanism for weight reduction in a ketogenic diet?

Increased lipolysis

Why is moderate protein intake crucial in a ketogenic diet?

To prevent muscle protein from converting to glucose

What alternative source of energy does the brain utilize in a ketogenic diet?

Ketone bodies

Study Notes

Nonpathological Forms of Ketosis

  • Ketosis occurs when the body is fed a high-fat, low-carbohydrate diet or after severe exercise.
  • Excess formation of acetoacetate and 3-hydroxybutyrate, both moderately strong acids, can lead to ketoacidosis, a potentially fatal condition, especially in uncontrolled diabetes mellitus.

Keto Diet (Ketogenic Diet)

  • The ketogenic diet is a low-carbohydrate, moderate-protein, high-fat diet that induces ketosis without ketoacidosis.
  • This diet can be used for weight reduction without compromising overall health.

Mechanism for Weight Reduction

  • A low-carbohydrate diet triggers the body to burn stored fat (lipolysis) for energy.
  • Reduced insulin secretion due to hypoglycemia (low blood sugar) reduces lipogenesis (fat storage).
  • Increased glucagon secretion due to hypoglycemia stimulates lipolysis (fat breakdown).

Mechanism for Preserving Body Health

  • Moderate protein in the ketogenic diet preserves lean body mass, including muscles, without excess protein conversion to glucose.
  • Ketone bodies produced in the ketogenic diet serve as an alternative source of brain energy, mitigating the negative effects of low glucose levels on the brain.

Learn about nonpathological forms of ketosis, its relation to ketoacidosis, and the ketogenic diet for weight reduction.

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