32 Mineralocorticoid Excess
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Questions and Answers

Which of the following is a symptom of primary hyperaldosteronism?

  • Hypertension (correct)
  • Hypokalemic acidosis
  • Hypercalcemia
  • Hypernatremia
  • What is the cause of low-renin hypertension in primary hyperaldosteronism?

  • Excessive aldosterone breakdown
  • Increased renin production
  • Inhibition of renin secretion (correct)
  • Renal artery stenosis
  • What is the most common cause of primary hyperaldosteronism?

  • Bilateral adrenal hyperplasia
  • Excessive aldosterone production
  • Renal artery stenosis
  • Unilateral adenoma (correct)
  • Which medication is commonly used to restore intravascular fluid volume and electrolyte concentrations in primary hyperaldosteronism?

    <p>Spironolactone</p> Signup and view all the answers

    How long does it take for the effects of spironolactone to increase after administration?

    <p>1 to 2 weeks</p> Signup and view all the answers

    Why is a period of at least 24 hours required to restore potassium equilibrium in primary hyperaldosteronism?

    <p>The deficit can be up to 400 mEq</p> Signup and view all the answers

    What is the high incidence of hypertension and ischemic heart disease in patients with Conn syndrome attributed to?

    <p>Conn syndrome itself</p> Signup and view all the answers

    What should be done preoperatively in patients with primary hyperaldosteronism?

    <p>Restore intravascular fluid volume and electrolyte concentrations</p> Signup and view all the answers

    What was the finding of a retrospective anecdotal study regarding intraoperative hemodynamic status in patients with Conn syndrome?

    <p>More stable when controlled with spironolactone</p> Signup and view all the answers

    What is the frequency of primary hyperaldosteronism in hypertensive patients with no other known cause of hypertension?

    <p>0.5% to 1%</p> Signup and view all the answers

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