Isotonic Fluids Overview
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Questions and Answers

What is the primary use of 0.9% NaCl (Normal Saline)?

  • Treatment of severe dehydration
  • Routine maintenance solution
  • Only solution administered with blood products (correct)
  • Management of chronic renal failure
  • Which fluid is contraindicated in patients with hyperglycemia during fluid resuscitation?

  • 0.45% NaCl (half strength saline)
  • D5W - 5% Dextrose in water (correct)
  • Lactated Ringer’s Solution
  • 3% NaCl (hypertonic saline)
  • What is a possible complication of administering 3% NaCl too quickly?

  • Fluid overload (correct)
  • Peripheral circulatory collapse
  • Hypokalemia
  • Acute renal failure
  • Which solution provides both sodium and chloride but is contraindicated in patients with ph > 7.5?

    <p>Lactated Ringer’s Solution</p> Signup and view all the answers

    What is the normal range for serum phosphorus (PO4)?

    <p>2.5-4.5 mg/L</p> Signup and view all the answers

    In which fluid compartment is the majority of an average adult's body fluid located?

    <p>Intracellular</p> Signup and view all the answers

    What condition is best treated with 0.45% NaCl?

    <p>Hypotonic dehydration</p> Signup and view all the answers

    Which of the following is a symptom of hypochloremia?

    <p>Tetany</p> Signup and view all the answers

    What is the osmolarity of D10W - 10% Dextrose in water?

    <p>1011 mOsm/L</p> Signup and view all the answers

    What dietary restriction is recommended for management of hyperphosphatemia?

    <p>Limit dairy products</p> Signup and view all the answers

    Which of the following solutions is not suitable for treating fluid loss due to gastric fluids?

    <p>D5W</p> Signup and view all the answers

    Which hormone increases renal excretion of phosphorus?

    <p>Calcitonin</p> Signup and view all the answers

    In the case of hypophosphatemia, which clinical feature is least likely to be present?

    <p>Soft tissue calcification</p> Signup and view all the answers

    Which of the following is a potential cause of hypochloremia?

    <p>Severe vomiting</p> Signup and view all the answers

    What is the main nursing management intervention for hypophosphatemia?

    <p>Administer oral or IV phosphorus correction</p> Signup and view all the answers

    Which of the following best describes the effect when potassium levels are excessively high?

    <p>Cardiac arrest</p> Signup and view all the answers

    What effect does PTH have on calcium in the body?

    <p>It increases calcium resorption from bones.</p> Signup and view all the answers

    Which of the following is a symptom of hypercalcemia?

    <p>Nausea</p> Signup and view all the answers

    What is the definition of hypocalcemia?

    <p>Calcium level less than 8.5 mg/dL</p> Signup and view all the answers

    Which treatment is appropriate for managing hypercalcemia?

    <p>IV phosphate therapy</p> Signup and view all the answers

    What does calcitonin do regarding calcium levels?

    <p>Promotes urinary excretion of calcium.</p> Signup and view all the answers

    Which of the following could lead to hypocalcemia?

    <p>Inflammation of the pancreas</p> Signup and view all the answers

    Which of the following is a function of magnesium?

    <p>It aids in intracellular ATP production.</p> Signup and view all the answers

    What is the normal range for magnesium levels in the body?

    <p>1.3-2.1 mEq/L</p> Signup and view all the answers

    What indicates a state of metabolic alkalosis?

    <p>High plasma Bicarbonate</p> Signup and view all the answers

    Which of the following conditions is associated with metabolic acidosis?

    <p>Diarrhea</p> Signup and view all the answers

    What is the normal range for arterial pH?

    <p>7.35 - 7.45</p> Signup and view all the answers

    What does a PaCO2 level greater than 42 mmHg indicate?

    <p>Respiratory acidosis</p> Signup and view all the answers

    Which symptom is most likely associated with respiratory alkalosis?

    <p>Dizziness</p> Signup and view all the answers

    Which condition is NOT typically associated with metabolic acidosis?

    <p>Hypokalemia</p> Signup and view all the answers

    Which intervention is appropriate for treating respiratory acidosis?

    <p>Improving ventilation</p> Signup and view all the answers

    Which measurement would indicate uncompensated metabolic acidosis?

    <p>Decreased pH with normal bicarbonate</p> Signup and view all the answers

    What serum magnesium level indicates hypermagnesemia?

    <p>Greater than 2.1 mEq/L</p> Signup and view all the answers

    Which of the following symptoms is not associated with hypermagnesemia?

    <p>Tetany</p> Signup and view all the answers

    What is a common cause of hypomagnesemia?

    <p>Alcohol withdrawal</p> Signup and view all the answers

    Which of the following management strategies is appropriate for treating hypermagnesemia?

    <p>Administer IV Calcium Gluconate</p> Signup and view all the answers

    What is the normal range for serum chloride?

    <p>95-108 mEq/L</p> Signup and view all the answers

    Which of the following choices correlates with hyperchloremia?

    <p>Loss of bicarbonate ions</p> Signup and view all the answers

    Which clinical finding would indicate the need for seizure precautions in a patient with hypomagnesemia?

    <p>Prolonged PR and QT intervals</p> Signup and view all the answers

    How does chloride function as a chemical buffer?

    <p>By participating in the chloride shift</p> Signup and view all the answers

    Study Notes

    Isotonic Fluids

    • 0.9% NaCl (Normal Saline/NSS): Contains 154 mEq/L Na and Cl, osmolarity of 308 mOsm/L. Used for hypovolemia, shock, DKA, metabolic alkalosis, hypercalcemia, and mild Na deficiency. Caution in renal failure, heart failure, and edema.
    • D5W (5% Dextrose in Water): Provides 170 calories and free water, osmolarity of 252 mOsm/L. Indicated for hypernatremia and dehydration. Contraindicated post-op due to increased ADH, and in conditions leading to fluid overload or hyperglycemia.
    • Lactated Ringer’s Solution: Contains Na 130 mEq/L, K 4 mEq/L, Ca 3 mEq/L, Cl 109 mEq/L, with osmolarity of 273 mOsm/L. Used for hypovolemia, burns, and fluid losses. Caution in pH > 7.5 and lactic acidosis.

    Hypotonic Fluids

    • 0.45% NaCl (Half Strength Saline): Provides Na, Cl, and free water (77 mEq/L Na and Cl), osmolarity of 154 mOsm/L. Used for hypertonic dehydration and gastric fluid loss. Contraindicated with third space shifts and increased ICP.

    Hypertonic Fluids

    • 3% NaCl (Hypertonic Saline): Contains Na 513 mEq/L, Cl 513 mEq/L, osmolarity of 1026 mOsm/L. Used in critical situations to treat hyponatremia and for ICF excess removal. Requires cautious administration.
    • D10W (10% Dextrose in Water): Hypertonic with osmolarity of 505 mOsm/L.
    • D50W (50% Dextrose in Water): High osmolarity of 1700 mOsm/L.
    • D5NS (5% Dextrose & 0.9% NaCl): Hypertonic, osmolarity 559 mOsm/L.

    Body Fluid Compartments

    • Adults are approximately 60% water, predominantly in the intracellular compartment.

    Regulation of Calcium

    • GIT: Absorbs calcium with Vitamin D.
    • Kidneys: Filter calcium, reabsorbing it in the tubules.
    • PTH (Parathyroid Hormone): Increases serum calcium by stimulating bone resorption, intestinal absorption, and renal reabsorption.
    • Calcitonin: Lowers serum calcium by promoting bone deposition and urinary excretion.

    Calcium Disorders

    • Hypercalcemia: Serum calcium > 10.5 mg/dL. Etiology includes excess supplements and malignancy. Symptoms include nausea, weakness, and lethargy. Management involves hydration, diuretics, and dietary restrictions.
    • Hypocalcemia: Serum calcium < 8.5 mg/dL. Causes include vitamin D deficiency and thyroid surgery. Symptoms include tetany and seizures. Management includes calcium and vitamin D supplementation.

    Magnesium

    • Normal range: 1.3-2.1 mEq/L. Functions include ATP production, protein synthesis, and neuromuscular transmission.

    Magnesium Disorders

    • Hypermagnesemia: Serum magnesium > 2.1 mEq/L, often due to renal failure. Symptoms include lethargy and hypotension. Management includes discontinuing magnesium and dialysis.
    • Hypomagnesemia: Serum magnesium < 1.5 mEq/L, causes range from alcoholism to GIT losses. Symptoms include muscle weakness and ECG changes. Treatment includes dietary intake and IV magnesium.

    Anions

    • Major anions include Chloride (Cl), Phosphates (PO4), and Bicarbonates (HCO3).

    Chloride Disorders

    • Hyperchloremia: Serum Cl > 108 mEq/L, often linked to sodium excess. Symptoms include lethargy and hypertension. Management includes lactated ringers and monitoring.
    • Hypochloremia: Serum Cl < 96 mEq/L. Symptoms include muscle cramps and dysrhythmias. Management includes saline solutions and diet high in Cl-rich foods.

    Phosphate Disorders

    • Hyperphosphatemia: Serum PO4 > 4.5 mg/dL; symptoms include muscle weakness and fatigue. Management includes dietary restrictions and dialysis.
    • Hypophosphatemia: Serum PO4 < 2.5 mg/dL; symptoms include irritability and weakness. Treatment involves phosphorus replacement and dietary adjustment.

    Acid-Base Disturbances

    • Acidosis: pH < 7.35, characterized by increased H+ ions.
    • Alkalosis: pH > 7.45, characterized by decreased H+ ions.

    Metabolic Acidosis

    • Features low pH, increased H ions, and reduced bicarbonate. Common causes are diarrhea and renal insufficiency. Symptoms include confusion and hypotension. Treatment can include bicarbonate administration and hemodialysis.

    Metabolic Alkalosis

    • High pH, decreased H ions, increased bicarbonate, often due to vomiting. Symptoms include muscle twitching and dizziness.

    Respiratory Acidosis

    • Low pH and elevated carbon dioxide levels, typically from pulmonary issues. Management focuses on improving ventilation.

    Respiratory Alkalosis

    • High pH and low carbon dioxide, often due to anxiety. Treatment may involve calming techniques.

    Arterial Blood Gas Analysis

    • Normal values: pH 7.35–7.45, PaCO2 35–45 mmHg, HCO3 22-26 mEq/L, O2 saturation 93-98%. Assess pH for acidosis or alkalosis and determine the primary cause of disturbance.

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    Description

    This quiz covers the key aspects of isotonic fluids, focusing on 0.9% NaCl and D5W solutions. It discusses their composition, indications for use, and contraindications in clinical settings. Ideal for students learning about fluid therapy in medical courses.

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