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Questions and Answers
What is the primary use of 0.9% NaCl (Normal Saline)?
What is the primary use of 0.9% NaCl (Normal Saline)?
Which fluid is contraindicated in patients with hyperglycemia during fluid resuscitation?
Which fluid is contraindicated in patients with hyperglycemia during fluid resuscitation?
What is a possible complication of administering 3% NaCl too quickly?
What is a possible complication of administering 3% NaCl too quickly?
Which solution provides both sodium and chloride but is contraindicated in patients with ph > 7.5?
Which solution provides both sodium and chloride but is contraindicated in patients with ph > 7.5?
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What is the normal range for serum phosphorus (PO4)?
What is the normal range for serum phosphorus (PO4)?
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In which fluid compartment is the majority of an average adult's body fluid located?
In which fluid compartment is the majority of an average adult's body fluid located?
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What condition is best treated with 0.45% NaCl?
What condition is best treated with 0.45% NaCl?
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Which of the following is a symptom of hypochloremia?
Which of the following is a symptom of hypochloremia?
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What is the osmolarity of D10W - 10% Dextrose in water?
What is the osmolarity of D10W - 10% Dextrose in water?
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What dietary restriction is recommended for management of hyperphosphatemia?
What dietary restriction is recommended for management of hyperphosphatemia?
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Which of the following solutions is not suitable for treating fluid loss due to gastric fluids?
Which of the following solutions is not suitable for treating fluid loss due to gastric fluids?
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Which hormone increases renal excretion of phosphorus?
Which hormone increases renal excretion of phosphorus?
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In the case of hypophosphatemia, which clinical feature is least likely to be present?
In the case of hypophosphatemia, which clinical feature is least likely to be present?
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Which of the following is a potential cause of hypochloremia?
Which of the following is a potential cause of hypochloremia?
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What is the main nursing management intervention for hypophosphatemia?
What is the main nursing management intervention for hypophosphatemia?
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Which of the following best describes the effect when potassium levels are excessively high?
Which of the following best describes the effect when potassium levels are excessively high?
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What effect does PTH have on calcium in the body?
What effect does PTH have on calcium in the body?
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Which of the following is a symptom of hypercalcemia?
Which of the following is a symptom of hypercalcemia?
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What is the definition of hypocalcemia?
What is the definition of hypocalcemia?
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Which treatment is appropriate for managing hypercalcemia?
Which treatment is appropriate for managing hypercalcemia?
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What does calcitonin do regarding calcium levels?
What does calcitonin do regarding calcium levels?
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Which of the following could lead to hypocalcemia?
Which of the following could lead to hypocalcemia?
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Which of the following is a function of magnesium?
Which of the following is a function of magnesium?
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What is the normal range for magnesium levels in the body?
What is the normal range for magnesium levels in the body?
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What indicates a state of metabolic alkalosis?
What indicates a state of metabolic alkalosis?
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Which of the following conditions is associated with metabolic acidosis?
Which of the following conditions is associated with metabolic acidosis?
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What is the normal range for arterial pH?
What is the normal range for arterial pH?
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What does a PaCO2 level greater than 42 mmHg indicate?
What does a PaCO2 level greater than 42 mmHg indicate?
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Which symptom is most likely associated with respiratory alkalosis?
Which symptom is most likely associated with respiratory alkalosis?
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Which condition is NOT typically associated with metabolic acidosis?
Which condition is NOT typically associated with metabolic acidosis?
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Which intervention is appropriate for treating respiratory acidosis?
Which intervention is appropriate for treating respiratory acidosis?
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Which measurement would indicate uncompensated metabolic acidosis?
Which measurement would indicate uncompensated metabolic acidosis?
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What serum magnesium level indicates hypermagnesemia?
What serum magnesium level indicates hypermagnesemia?
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Which of the following symptoms is not associated with hypermagnesemia?
Which of the following symptoms is not associated with hypermagnesemia?
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What is a common cause of hypomagnesemia?
What is a common cause of hypomagnesemia?
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Which of the following management strategies is appropriate for treating hypermagnesemia?
Which of the following management strategies is appropriate for treating hypermagnesemia?
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What is the normal range for serum chloride?
What is the normal range for serum chloride?
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Which of the following choices correlates with hyperchloremia?
Which of the following choices correlates with hyperchloremia?
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Which clinical finding would indicate the need for seizure precautions in a patient with hypomagnesemia?
Which clinical finding would indicate the need for seizure precautions in a patient with hypomagnesemia?
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How does chloride function as a chemical buffer?
How does chloride function as a chemical buffer?
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Study Notes
Isotonic Fluids
- 0.9% NaCl (Normal Saline/NSS): Contains 154 mEq/L Na and Cl, osmolarity of 308 mOsm/L. Used for hypovolemia, shock, DKA, metabolic alkalosis, hypercalcemia, and mild Na deficiency. Caution in renal failure, heart failure, and edema.
- D5W (5% Dextrose in Water): Provides 170 calories and free water, osmolarity of 252 mOsm/L. Indicated for hypernatremia and dehydration. Contraindicated post-op due to increased ADH, and in conditions leading to fluid overload or hyperglycemia.
- Lactated Ringer’s Solution: Contains Na 130 mEq/L, K 4 mEq/L, Ca 3 mEq/L, Cl 109 mEq/L, with osmolarity of 273 mOsm/L. Used for hypovolemia, burns, and fluid losses. Caution in pH > 7.5 and lactic acidosis.
Hypotonic Fluids
- 0.45% NaCl (Half Strength Saline): Provides Na, Cl, and free water (77 mEq/L Na and Cl), osmolarity of 154 mOsm/L. Used for hypertonic dehydration and gastric fluid loss. Contraindicated with third space shifts and increased ICP.
Hypertonic Fluids
- 3% NaCl (Hypertonic Saline): Contains Na 513 mEq/L, Cl 513 mEq/L, osmolarity of 1026 mOsm/L. Used in critical situations to treat hyponatremia and for ICF excess removal. Requires cautious administration.
- D10W (10% Dextrose in Water): Hypertonic with osmolarity of 505 mOsm/L.
- D50W (50% Dextrose in Water): High osmolarity of 1700 mOsm/L.
- D5NS (5% Dextrose & 0.9% NaCl): Hypertonic, osmolarity 559 mOsm/L.
Body Fluid Compartments
- Adults are approximately 60% water, predominantly in the intracellular compartment.
Regulation of Calcium
- GIT: Absorbs calcium with Vitamin D.
- Kidneys: Filter calcium, reabsorbing it in the tubules.
- PTH (Parathyroid Hormone): Increases serum calcium by stimulating bone resorption, intestinal absorption, and renal reabsorption.
- Calcitonin: Lowers serum calcium by promoting bone deposition and urinary excretion.
Calcium Disorders
- Hypercalcemia: Serum calcium > 10.5 mg/dL. Etiology includes excess supplements and malignancy. Symptoms include nausea, weakness, and lethargy. Management involves hydration, diuretics, and dietary restrictions.
- Hypocalcemia: Serum calcium < 8.5 mg/dL. Causes include vitamin D deficiency and thyroid surgery. Symptoms include tetany and seizures. Management includes calcium and vitamin D supplementation.
Magnesium
- Normal range: 1.3-2.1 mEq/L. Functions include ATP production, protein synthesis, and neuromuscular transmission.
Magnesium Disorders
- Hypermagnesemia: Serum magnesium > 2.1 mEq/L, often due to renal failure. Symptoms include lethargy and hypotension. Management includes discontinuing magnesium and dialysis.
- Hypomagnesemia: Serum magnesium < 1.5 mEq/L, causes range from alcoholism to GIT losses. Symptoms include muscle weakness and ECG changes. Treatment includes dietary intake and IV magnesium.
Anions
- Major anions include Chloride (Cl), Phosphates (PO4), and Bicarbonates (HCO3).
Chloride Disorders
- Hyperchloremia: Serum Cl > 108 mEq/L, often linked to sodium excess. Symptoms include lethargy and hypertension. Management includes lactated ringers and monitoring.
- Hypochloremia: Serum Cl < 96 mEq/L. Symptoms include muscle cramps and dysrhythmias. Management includes saline solutions and diet high in Cl-rich foods.
Phosphate Disorders
- Hyperphosphatemia: Serum PO4 > 4.5 mg/dL; symptoms include muscle weakness and fatigue. Management includes dietary restrictions and dialysis.
- Hypophosphatemia: Serum PO4 < 2.5 mg/dL; symptoms include irritability and weakness. Treatment involves phosphorus replacement and dietary adjustment.
Acid-Base Disturbances
- Acidosis: pH < 7.35, characterized by increased H+ ions.
- Alkalosis: pH > 7.45, characterized by decreased H+ ions.
Metabolic Acidosis
- Features low pH, increased H ions, and reduced bicarbonate. Common causes are diarrhea and renal insufficiency. Symptoms include confusion and hypotension. Treatment can include bicarbonate administration and hemodialysis.
Metabolic Alkalosis
- High pH, decreased H ions, increased bicarbonate, often due to vomiting. Symptoms include muscle twitching and dizziness.
Respiratory Acidosis
- Low pH and elevated carbon dioxide levels, typically from pulmonary issues. Management focuses on improving ventilation.
Respiratory Alkalosis
- High pH and low carbon dioxide, often due to anxiety. Treatment may involve calming techniques.
Arterial Blood Gas Analysis
- Normal values: pH 7.35–7.45, PaCO2 35–45 mmHg, HCO3 22-26 mEq/L, O2 saturation 93-98%. Assess pH for acidosis or alkalosis and determine the primary cause of disturbance.
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Description
This quiz covers the key aspects of isotonic fluids, focusing on 0.9% NaCl and D5W solutions. It discusses their composition, indications for use, and contraindications in clinical settings. Ideal for students learning about fluid therapy in medical courses.