physiology 1404 lect 3
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Questions and Answers

What is the term for the amount of a substance filtered per unit time?

  • Secretion Rate
  • Reabsorption Rate
  • Filtered Load (correct)
  • Urinary Excretion Rate

Which process involves the movement of substances from the peritubular capillary blood into the tubules?

  • Urinary Excretion
  • Tubular Reabsorption
  • Tubular Secretion (correct)
  • Glomerular Filtration

What is the term for the balance between the amount of fluid and solutes reabsorbed in the proximal tubule and the amount filtered by the glomerulus?

  • Glomerulotubular Balance (correct)
  • Renal-Hepatic Balance
  • Proximal-Distal Balance
  • Tubuloglomerular Balance

In which segment of the nephron is isosmotic reabsorption of NaCl observed?

<p>Late Proximal Tubule (A)</p> Signup and view all the answers

What is the term for the process by which substances are reabsorbed from the filtrate back into the bloodstream?

<p>Reabsorption (D)</p> Signup and view all the answers

What is the term for the rate at which a substance is excreted in the urine?

<p>Urinary Excretion Rate (A)</p> Signup and view all the answers

What is the primary function of transporters in the membranes of renal tubule epithelial cells?

<p>Reabsorption and secretion of substances into the peritubular capillary blood (C)</p> Signup and view all the answers

Which of the following substances is NOT reabsorbed from the glomerular filtrate into the peritubular capillary blood?

<p>K+ (B)</p> Signup and view all the answers

What is the excretion rate of a substance equivalent to?

<p>The amount of a substance excreted per unit time (B)</p> Signup and view all the answers

What is the purpose of measuring the filtered load and excretion rate of a substance?

<p>To determine whether a substance has been reabsorbed or secreted (B)</p> Signup and view all the answers

What is the formula for calculating the filtered load of a substance?

<p>GFR x [Px] (D)</p> Signup and view all the answers

What can be inferred if a substance is present in the urine?

<p>It may have entered the renal tubule by either filtration or secretion (A)</p> Signup and view all the answers

Why would glucose molecules be excreted in the urine when the glucose concentration in the tubular fluid rises?

<p>Because there are few remaining 'free' transporters to which they may re-attach (B)</p> Signup and view all the answers

What is the significance of Tm in the context of renal handling of glucose?

<p>It is the maximum amount of glucose that can be reabsorbed in the tubules (B)</p> Signup and view all the answers

Why does glucosuria occur in uncontrolled diabetes mellitus?

<p>Because the plasma glucose concentration exceeds Tm (D)</p> Signup and view all the answers

What is the effect of pregnancy on the renal handling of glucose?

<p>It increases the filtered load of glucose (A)</p> Signup and view all the answers

What is the consequence of congenital abnormalities of the Na+ glucose cotransporter?

<p>Decreased Tm (D)</p> Signup and view all the answers

What is the formula to calculate the amount of a substance filtered per unit time?

<p>GFR x filterable plasma concentration of the substance (A)</p> Signup and view all the answers

What is the main characteristic of isosmotic reabsorption in the PT?

<p>Solute and water reabsorption are coupled and proportional to each other (C)</p> Signup and view all the answers

What is the primary function of the Na+-K+ ATPase in the PT?

<p>To pump Na+ out of the cell and maintain isosmolarity (C)</p> Signup and view all the answers

What is the effect of increased filtered load on reabsorption in the PT?

<p>No change in reabsorption of isosmotic fluid (C)</p> Signup and view all the answers

What is the primary mechanism of glomerulotubular balance in the PT?

<p>Balance between filtration and reabsorption (D)</p> Signup and view all the answers

What is the primary function of Starling's forces in the peritubular capillary?

<p>To favor reabsorption of isosmotic fluid (C)</p> Signup and view all the answers

What is the percentage of the filtered load that is reabsorbed by the PT?

<p>67% (C)</p> Signup and view all the answers

What is the primary function of the early distal tubule in terms of sodium reabsorption?

<p>Reabsorption of sodium ions in an electro-neutral manner (C)</p> Signup and view all the answers

What is the effect of thiazide diuretics on the Na+-Cl- cotransporter in the early distal tubule?

<p>They inhibit the transporter, causing a decrease in sodium reabsorption (A)</p> Signup and view all the answers

What is the primary function of principal cells in the late distal tubule and collecting duct?

<p>Reabsorption of sodium ions and secretion of potassium ions (B)</p> Signup and view all the answers

What is the mechanism of sodium reabsorption in the late distal tubule and collecting duct?

<p>Sodium ions diffuse through Na+ channels on the luminal membrane and are then pumped out of the cell by Na+-K+-ATPase (C)</p> Signup and view all the answers

What is the effect of aldosterone on sodium reabsorption in the late distal tubule and collecting duct?

<p>It stimulates sodium reabsorption in the principal cells (D)</p> Signup and view all the answers

What is the effect of K+-sparing diuretics on sodium reabsorption in the late distal tubule and collecting duct?

<p>They inhibit sodium reabsorption in the principal cells (B)</p> Signup and view all the answers

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