Isomerism in Organic Chemistry

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Questions and Answers

What is the correct order of priority for functional groups in a molecule?

  • H(1) > C(6) > N(7) > F(9)
  • N(7) > F(9) > C(6) > H(1)
  • F(9) > N(7) > C(6) > H(1) (correct)
  • C(6) > N(7) > F(9) > H(1)

What is the term for molecules with two or more chiral carbons that exist as non-mirror images of each other?

  • Mesomers
  • Enantiomers
  • Stereoisomers
  • Diastereomers (correct)

What is the characteristic of a good leaving group in a substitution reaction?

  • It forms a stable anion (correct)
  • It is a strong electron donor
  • It is the conjugate acid of a strong base
  • It is a poor nucleophile

What is the rate-limiting step of an SN1 substitution reaction?

<p>Unimolecular rate-limiting step (A)</p> Signup and view all the answers

Why must alcohols be activated in an SN1 substitution reaction?

<p>Because they are poor leaving groups (C)</p> Signup and view all the answers

What is the type of substrate that can undergo an SN1 substitution reaction?

<p>Sp3 hybridized (B)</p> Signup and view all the answers

What is the primary difference between constitutional isomers?

<p>Their molecular formulas and physical/chemical properties (C)</p> Signup and view all the answers

What is the term for the type of isomerism that occurs when there is restricted rotation around double bonds in an alkene?

<p>Geometric isomerism (C)</p> Signup and view all the answers

What is the priority of the functional group attached to the alkene carbon based on atomic number?

<p>C(6) &gt; H(1) &gt; CH3 (C)</p> Signup and view all the answers

What is the term used to describe the arrangement of the four groups attached to the asymmetric carbon in enantiomers?

<p>Configuration (B)</p> Signup and view all the answers

How are the asymmetric carbon atoms assigned in enantiomers?

<p>Based on their three-dimensional configurations (D)</p> Signup and view all the answers

What is the primary difference between cis (Z) and trans (E) isomers?

<p>Their positions of functional groups on the same or opposite side of the carbon chain (D)</p> Signup and view all the answers

What is the result of a planar carbocation intermediate in a reaction?

<p>Loss of stereochemistry at the reacting centre (A)</p> Signup and view all the answers

What type of solvents favour E2 elimination reactions?

<p>Polar aprotic solvents (A)</p> Signup and view all the answers

What is the shape of the transition state in an SN2 reaction?

<p>Trigonal bipyramidal (B)</p> Signup and view all the answers

Which type of nucleophiles are more reactive?

<p>Anionic nucleophiles (B)</p> Signup and view all the answers

What is the rate-limiting step in an E1 elimination reaction?

<p>Unimolecular (B)</p> Signup and view all the answers

What type of nucleophiles are based on atoms lower down the periodic table?

<p>More reactive (A)</p> Signup and view all the answers

What is the outcome of the reaction between an achiral alkene and an electrophile?

<p>A racemic mixture (D)</p> Signup and view all the answers

Which reagent is used to convert an alkyne to a cis-alkene?

<p>Lindlar's catalyst (B)</p> Signup and view all the answers

What is the role of the strong base in the reaction with alkynes?

<p>To deprotonate the alkyne (C)</p> Signup and view all the answers

What is the product of the reaction between an alkyne and NaBH4?

<p>A cis-alkene (D)</p> Signup and view all the answers

Which reagent is used to convert an alkene to an epoxide?

<p>mCPBA (C)</p> Signup and view all the answers

What is the necessary condition for the E2 reaction to occur?

<p>The β-hydrogen atom and leaving group must be σCH anti-periplanar to each other. (D)</p> Signup and view all the answers

Which type of base favours the formation of the less substituted alkene in an E2 reaction?

<p>A large and bulky base. (A)</p> Signup and view all the answers

What is the regioselectivity of the E2 reaction?

<p>Formation of the more substituted alkene is favoured. (C)</p> Signup and view all the answers

Which reaction is stereospecific when there is only one β-hydrogen atom?

<p>E2 (A)</p> Signup and view all the answers

What is the effect of a strong base on the E2 reaction?

<p>It favours the reaction. (B)</p> Signup and view all the answers

What is the condition necessary for the formation of a stabilised carbocation?

<p>The ability to form a stabilised carbocation. (C)</p> Signup and view all the answers

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