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IsoFlux System: Circulating Tumor Cells and Molecular Profiling

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IsoFlux System: Circulating Tumor Cells and Molecular Profiling

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Questions and Answers

What is the primary benefit of the IsoFlux system beyond just capturing and counting circulating tumor cells?

To identify the specific type of tumor cells
To increase the sensitivity of CTC detection
To obtain genomic information from tumor cells through a routine blood draw (correct)
To enable real-time monitoring of CTCs

What is the typical purity of tumor cells obtained using the IsoFlux system?

Above 10% (correct)
Above 20%
Above 50%
Above 5%

What is the design of the IsoFlux system?

A benchtop design (correct)
A handheld, portable device
A large, floor-standing device
A complex, multi-component system

What type of analysis can be performed using the consumable kits and protocols provided with the IsoFlux system?

NGS, qPCR, and immunofluorescence microscopy (B) Signup and view all the answers

What is the significance of the IsoFlux system in molecular profiling of CTCs?

It is the premier platform for molecular profiling of CTCs (A) Signup and view all the answers

What is the primary purpose of the inertial focusing chamber in the microfluidic CTC-iChip system?

To align cells into a single file for further processing (C) Signup and view all the answers

What is the purpose of the magnetic field in the microfluidic CTC-iChip system?

To deflect cells previously labeled with tiny magnetic beads (A) Signup and view all the answers

Which cells are allowed to enter the inertial focusing chamber in the microfluidic CTC-iChip system?

CTCs and white blood cells (D) Signup and view all the answers

What is the result of the sorting process based on cell size in the microfluidic CTC-iChip system?

Only CTCs and white blood cells enter the inertial focusing chamber (A) Signup and view all the answers

What is the ultimate goal of the microfluidic CTC-iChip system?

To isolate CTCs for further study (B) Signup and view all the answers