Isoenzymes LDH Classification Quiz
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Questions and Answers

Which isoenzyme of creatine kinase (CK) is most common in the brain?

  • CK-MM
  • CK-BB (correct)
  • CK-MB
  • CK-NN

What is the primary function of creatine kinase?

  • Protein breakdown
  • Carbohydrate metabolism
  • DNA synthesis
  • ATP regeneration in muscle cells (correct)

In which condition would you typically observe pronounced elevation of serum LDH levels?

  • Hypoglycemia
  • Acute lymphoblastic anemia (correct)
  • Hyperthyroidism
  • Osteoporosis

In the context of LDH isoenzymes, what pattern is typically seen in bacterial meningitis?

<p>LDH-5 &gt; LDH-4 &gt; LDH-3 &gt; LDH-2 &gt; LDH-1 (D)</p> Signup and view all the answers

Which isoenzyme of creatine kinase (CK) is considered a hybrid type with mixed muscle and brain origin?

<p>CK-BB (B)</p> Signup and view all the answers

Which isoenzyme is the major isoenzyme found in the heart and red blood cells?

<p>LDH-2 (HHHM) (A)</p> Signup and view all the answers

Which isoenzyme is indicative of liver injury or hepatic inflammation?

<p>LDH-4 (HMMM) (D)</p> Signup and view all the answers

Which isoenzyme is considered the most labile (unstable) enzyme?

<p>LDH-5 (MMMM) (B)</p> Signup and view all the answers

Which of the following conditions can lead to an increase in both LDH-5 and LDH-6 levels?

<p>Cardiovascular failure (B)</p> Signup and view all the answers

Which isoenzyme measurement method is considered the reference method?

<p>Electrophoresis (D)</p> Signup and view all the answers

Which of the following is a potential source of error in LDH assays?

<p>Hemolysis (A)</p> Signup and view all the answers

What is the preferred specimen for measuring serum aldolase levels?

<p>Plasma (C)</p> Signup and view all the answers

Which of the following is NOT a potential source of error when measuring enzyme activity?

<p>Use of certified reference materials (D)</p> Signup and view all the answers

Which isoenzyme is used as the indicator reaction in the Karmen method for measuring enzyme activity?

<p>Malate dehydrogenase (MD) (A)</p> Signup and view all the answers

Which of the following statements about the CK-MB isoenzyme is correct?

<p>It is elevated in cases of myocardial infarction (D)</p> Signup and view all the answers

What is the reference range for serum lactate dehydrogenase (LDH) levels?

<p>5 - 35 U/L (A)</p> Signup and view all the answers

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