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Questions and Answers
Which of the following is an oral iron medication used to treat iron deficiency anemia?
Which of the following is an oral iron medication used to treat iron deficiency anemia?
- Epoetin alfa
- Ferrous sulfate (correct)
- Iron dextran
- Deferoxamine
What is the black box warning associated with parenteral iron preparations?
What is the black box warning associated with parenteral iron preparations?
- Dark stool
- Anaphylactic shock (correct)
- Constipation
- Gastrointestinal bleeding
Which type of anemia is characterized by a decrease in erythropoietin (EPO)?
Which type of anemia is characterized by a decrease in erythropoietin (EPO)?
- Normocytic anemia (correct)
- Iron deficiency anemia
- Hemolytic anemia
- Aplastic anemia
What is the primary treatment for aplastic anemia?
What is the primary treatment for aplastic anemia?
What characterizes hemolytic anemia?
What characterizes hemolytic anemia?
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Study Notes
- Iron deficiency anemia: characterized by decreased iron levels in the body, leading to a need for supplementation with ferrous sulfate or ferrous fumate. Side effects may include gastrointestinal symptoms and dark stools. Copper and vitamin C are essential for iron absorption. Oral iron dose is typically 325 mg three times a day, providing 65 mg of elemental iron per dose. Deferoxamine is an antidote for iron overdose, acting through a non-receptor mechanism of binding to free iron. Parenteral iron is restricted due to black box warning of anaphylactic shock. The body stores iron as hemosiderin and ferritin.
- Normocytic anemia: caused by decreased erythropoietin (EPO) production, leading to a need for erythropoiesis-stimulating agents such as epoetin alfa, epoetin beta, and darbepoetin.
- Aplastic anemia: characterized by bone marrow failure to produce red blood cells. Treatment options include immunosuppressants, blood transfusions, and bone marrow transplantation.
- Hemolytic anemia: characterized by destroyed and removed red blood cells before their lifespan. No specific mention of causes or treatments in the text.
- Erythropoiesis: the process of producing red blood cells in the body. Erythropoiesis-stimulating agents (ESAs) are used to stimulate this process in anemia.
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