Introductory Cancer Biology Quiz

Study Notes

Growth Disorders

Common growth disorders include dwarfism, gigantism, and acromegaly.
An example of a condition not classified as a growth disorder would be cancer.

Tumour Biology Principles

Tumours can be benign (non-cancerous) or malignant (cancerous); malignant tumours invade surrounding tissues.
The process of metastasis involves the spread of cancer cells to distant sites in the body.
Tumourigenesis occurs through multiple stages including initiation, promotion, and progression.
Genetic mutations drive the development of tumours, affecting oncogenes and tumour suppressor genes.
The microenvironment of a tumour, including immune cells and blood vessels, plays a crucial role in tumor growth and survival.

Recommended Texts for Cancer Biology

Key textbooks often recommended include "The Biology of Cancer" by Weinberg and "Cancer Biology" by R. A. Weinberg.
Texts not commonly listed as core references may include unrelated medical textbooks or those focused on other diseases.

Causes of Cell Injury

Hypoxia and ischemia lead to reduced oxygen supply and can damage cells.
Chemical exposure, including toxins and drugs, can impair cellular function.
Infectious agents such as viruses and bacteria can invade and destroy cells.
Physical agents like extreme temperature or radiation can cause direct cell damage.

Cellular Adaptation Response

Normal responses to stress include hypertrophy (increased cell size) and hyperplasia (increased cell number).
Atrophy refers to a decrease in tissue size, often due to disuse or decreased demand.
Metaplasia involves a change in cell type in response to stress, aiming to better suit the environment.

Description

Test your knowledge of introductory cancer biology with this quiz covering general principles of tumor biology, types of growth disorders, and the hallmarks of cancer. Recommended reading includes 'The Biology of Cancer' by Robert Weinberg and other useful books in the field.