Introduction to Virology & Virus Structure and Classification Quiz
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Questions and Answers

What is the main role of the capsid in a virus?

  • To protect the viral genomic material from environmental factors (correct)
  • To help the virus recognize and bind to cells in the host organism
  • To ensure the delivery of the viral envelope into the host cell
  • To assist in the transmission of genetic material into the host cell
  • Which of the following is a function of viral envelope proteins?

  • Formation of the capsid shell
  • Recognition by cellular receptors (correct)
  • Transmission of genetic material into the host cell
  • Stabilization of viral genomic material
  • What distinguishes non-enveloped viruses from enveloped viruses?

  • Enveloped viruses have a protein coat known as a capsid
  • Non-enveloped viruses cause more cellular damage
  • Non-enveloped viruses are more resistant to environmental conditions (correct)
  • Enveloped viruses have a lipid bilayer with glycoproteins
  • What is the role of capsomers in a virus?

    <p>To form clusters of proteins that compose the capsid</p> Signup and view all the answers

    In viral classification, what is responsible for grouping viruses based on their manner of messenger RNA (mRNA) synthesis?

    <p>Baltimore classification system</p> Signup and view all the answers

    Which virus is named after the disease it causes?

    <p>Hepatitis virus</p> Signup and view all the answers

    What is a complete virus particle called?

    <p>Virion</p> Signup and view all the answers

    'A susceptible and permissive cell' is defined as:

    <p>A cell with a functional receptor for a given virus and able to support viral replication</p> Signup and view all the answers

    What distinguishes enveloped viruses from non-enveloped viruses?

    <p>Enveloped viruses usually cause more cellular damage</p> Signup and view all the answers

    What distinguishes non-enveloped viruses from enveloped viruses?

    <p>Non-enveloped viruses are more resistant to pH, heat, dryness, alcohol, soap</p> Signup and view all the answers

    What is the definition of viral pathogenesis?

    <p>The process by which a virus causes a disease</p> Signup and view all the answers

    How is viral virulence quantitated?

    <p>All of the above</p> Signup and view all the answers

    What is the meaning of 'signs' in the context of disease symptoms?

    <p>What others detect</p> Signup and view all the answers

    Which of the following is NOT an influencing factor on viral virulence?

    <p>Mean time to appearance of signs</p> Signup and view all the answers

    What is the burden of viral disease in terms of human deaths each year?

    <p>2-3 million deaths</p> Signup and view all the answers

    Which virus caused 10% of child mortality in the developing world due to diarrheal and vomiting in conjunction with malnutrition?

    <p>Enterovirus</p> Signup and view all the answers

    How many individuals were infected with HIV in 2012?

    <p>34 million</p> Signup and view all the answers

    What was the death toll due to HIV/AIDS in 2012?

    <p>2.1 million</p> Signup and view all the answers

    All viruses have a lipid membrane called an envelope.

    <p>False</p> Signup and view all the answers

    The viral envelope is made from fatty lipid molecules taken from the host cells.

    <p>True</p> Signup and view all the answers

    Non-enveloped viruses are more resistant to environmental conditions like pH, heat, and dryness.

    <p>True</p> Signup and view all the answers

    The main role of the capsid is to protect the viral genomic material.

    <p>True</p> Signup and view all the answers

    Capsomers are clusters of proteins that compose the viral genetic material.

    <p>False</p> Signup and view all the answers

    The lipid bilayer of the viral envelope is involved in virus attachment to cells.

    <p>True</p> Signup and view all the answers

    Virus classification is responsible for grouping viruses based on their manner of messenger RNA (mRNA) synthesis.

    <p>False</p> Signup and view all the answers

    Naming viruses after scientists who first identified the virus is a common practice in virus nomenclature.

    <p>True</p> Signup and view all the answers

    Viruses share a one common ancestor and do not mutate or change.

    <p>False</p> Signup and view all the answers

    Viruses outnumber bacteria at a ratio of 10:1.

    <p>True</p> Signup and view all the answers

    A resistant cell has no receptor for a given virus and is not competent to support viral replication.

    <p>True</p> Signup and view all the answers

    The infectious life cycle of a virus includes stages such as attachment to cells, mRNA translation using host ribosomes, and egress (exit).

    <p>True</p> Signup and view all the answers

    Viral virulence is a fixed property and does not change based on the route of infection, species, age, sex, and susceptibility of the host.

    <p>False</p> Signup and view all the answers

    Signs in the context of disease symptoms refer to what only the individual can feel.

    <p>False</p> Signup and view all the answers

    Viral virulence can be quantitated based on the mean time to appearance of signs.

    <p>True</p> Signup and view all the answers

    The Burden of Viral Disease results in approximately 2-3 million deaths each year.

    <p>True</p> Signup and view all the answers

    Viral Pathogenesis refers to the process by which a virus creates a disease through the effects of viral infection and replication as well as the effects of host response (immune system).

    <p>True</p> Signup and view all the answers

    Virulence depends on the dose, route of infection, species, age, sex, and susceptibility of the host.

    <p>True</p> Signup and view all the answers

    Viral virulence is mainly influenced by the measurement of fever and weight loss.

    <p>False</p> Signup and view all the answers

    The capacity of a virus to cause disease in a host is known as Viral Virulence.

    <p>True</p> Signup and view all the answers

    Many signs and symptoms of disease are caused by the immune response.

    <p>True</p> Signup and view all the answers

    Viral virulence is a fixed property that cannot be compared between different viruses without considering various factors.

    <p>True</p> Signup and view all the answers

    Study Notes

    • Introduction to Virology & Virus structure and Classification is part of the BMS2037 course at the University of Surrey, taught by Dr. Marine Petit.
    • Viruses are obligate intracellular parasites with genetic material (DNA or RNA) and a protein coat (capsid), sometimes an envelope (lipid bilayer) taken from the host cells.
    • Capsid's role is to protect the viral genomic material, which is usually DNA or RNA.
    • The virus envelope is involved in attachment to cells and can help the virus avoid the immune response.
    • The capsid comes in three forms: helical, icosahedric, and scaffolded icosahedric.
    • Capsid assembly involves the formation of a capsid shell and the packaging of the viral genome inside.
    • The capsid has repeating protein structures and is a closed 3-dimensional structure.
    • Viruses are classified into a taxonomic system by the International Committee on Taxonomy of Viruses (ICTV), based on phenotypic characteristics.
    • Viruses are everywhere and are involved in a wide range of diseases, from gastroenteritis and respiratory infections to zoonotic diseases.
    • The viral life cycle consists of attachment to cells, entry and uncoating, mRNA synthesis, translation using host ribosomes, assembly, and egress.
    • Viral virulence refers to the capacity of a virus to cause disease in a host and can be quantitated through various methods, such as virus titer and mean time to death.
    • The Burden of Viral Disease causes 2-3 million deaths each year, with diseases such as enterovirus, measles, diarrheal and vomiting, influenza, and HIV (AIDS) being some of the most common.
    • The course, Introduction to Virology & Virus structure and Classification, covers topics such as clinical virology and diagnostics, the infectious cycle of virus replication mechanisms, and research methods in virology.

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    Description

    Test your knowledge of virology, virus structure, and classification with this quiz based on the BMS2037 Cellular Microbiology and Virology course. Explore topics such as how viruses infect cells, the global virome, and diseases caused by viruses.

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