Introduction to Respiratory Physiology
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Questions and Answers

Which of the following is NOT a function of the respiratory system?

  • Provides oxygen
  • Facilitates digestion (correct)
  • Regulates blood pH
  • Eliminates carbon dioxide
  • During pulmonary ventilation, what happens to the pressure inside the lungs when the diaphragm contracts?

  • Intrapleural pressure increases
  • Intrapleural pressure decreases
  • Intrapulmonary pressure increases
  • Intrapulmonary pressure decreases (correct)
  • Which of the following muscles is considered an accessory muscle of inspiration?

  • Internal intercostals
  • Sternocleidomastoid (correct)
  • External intercostals
  • Diaphragm
  • Which process primarily involves the exchange of gases between the alveoli and the blood?

    <p>External respiration (D)</p> Signup and view all the answers

    What influences the efficiency of pulmonary ventilation?

    <p>Altitude levels (C)</p> Signup and view all the answers

    What is the main function of internal respiration?

    <p>Exchange of gases between blood and tissue cells (B)</p> Signup and view all the answers

    During inhalation, what happens to the diaphragm?

    <p>It contracts and flattens (B)</p> Signup and view all the answers

    Which muscle primarily assists in normal quiet breathing?

    <p>External intercostal muscles (C)</p> Signup and view all the answers

    What occurs during exhalation in terms of thoracic cavity volume?

    <p>The volume of the thoracic cavity decreases (A)</p> Signup and view all the answers

    What is the primary role of the phrenic nerve?

    <p>Innervate the diaphragm (C)</p> Signup and view all the answers

    Which statement about pulmonary ventilation is accurate?

    <p>Lung pressure must be lower than atmospheric pressure for air to enter (D)</p> Signup and view all the answers

    Which of the following muscles assists with breathing during deep or difficult breaths?

    <p>Neck and shoulder muscles (B)</p> Signup and view all the answers

    What happens to the external intercostal muscles during inhalation?

    <p>They contract to help expand the rib cage (B)</p> Signup and view all the answers

    What effect does the diaphragm's descent have during normal quiet inhalation?

    <p>It produces a pressure difference of 1–3 mmHg. (A)</p> Signup and view all the answers

    Which of the following is primarily responsible for elevating the ribs during inhalation?

    <p>External intercostal muscle (A)</p> Signup and view all the answers

    What changes occur in the intrapleural pressure just before inhalation?

    <p>It is about 4 mmHg less than atmospheric pressure. (D)</p> Signup and view all the answers

    How much air is typically inhaled during strenuous breathing?

    <p>About 2–3 liters. (A)</p> Signup and view all the answers

    What is the primary role of accessory muscles of inspiration?

    <p>Involved in forced inspiration. (B)</p> Signup and view all the answers

    Which muscle is responsible for enlarging the upper rib cage during forced inhalation?

    <p>Scalene (D)</p> Signup and view all the answers

    What happens to the volume of the pleural cavity as the diaphragm and external intercostals contract?

    <p>The volume increases, lowering intrapleural pressure. (B)</p> Signup and view all the answers

    What is the effect of the external intercostal muscle contraction on the chest cavity?

    <p>It increases both anteroposterior and lateral diameters. (B)</p> Signup and view all the answers

    What does vital capacity (VC) represent in lung function?

    <p>The maximum volume of air that can be moved in and out of the lungs (C)</p> Signup and view all the answers

    Which of the following correctly defines inspiratory reserve volume (IRV)?

    <p>The extra volume of air that can be inhaled during maximal inspiration (A)</p> Signup and view all the answers

    Which lung volume capacity cannot be directly measured and represents air remaining in the lungs after forced expiration?

    <p>Residual volume (D)</p> Signup and view all the answers

    What is the function of functional residual capacity (FRC) in the respiratory system?

    <p>It indicates the volume of air left after normal expiration. (C)</p> Signup and view all the answers

    How is vital capacity (VC) calculated?

    <p>VC = Tidal volume + IRV + ERV (D)</p> Signup and view all the answers

    What causes the parietal and visceral pleurae to adhere closely during thoracic expansion?

    <p>Intrapleural pressure and surface tension from moisture (C)</p> Signup and view all the answers

    Which of the following demonstrates the active process of inhalation?

    <p>Forced breathing during exercise (D)</p> Signup and view all the answers

    During inhalation, the pressure inside the alveoli decreases. What is the typical alveolar pressure during this phase?

    <p>758 mmHg (D)</p> Signup and view all the answers

    What initiates the process of exhalation?

    <p>Relaxation of the inspiratory muscles (B)</p> Signup and view all the answers

    Which two forces contribute to the elastic recoil of the lungs during exhalation?

    <p>Elastic fiber recoil and surface tension (A)</p> Signup and view all the answers

    What happens to the thoracic cavity as the diaphragm relaxes during exhalation?

    <p>It decreases in vertical, lateral, and anteroposterior dimensions (C)</p> Signup and view all the answers

    Which of the following is a characteristic of normal quiet exhalation?

    <p>It is primarily a passive process (D)</p> Signup and view all the answers

    Air flows from areas of higher pressure to lower pressure. During inhalation, this is primarily due to:

    <p>Increased lung volume which reduces pressure inside (A)</p> Signup and view all the answers

    What does surface tension of the alveolar fluid primarily produce during inhalation?

    <p>An inwardly directed force that resists lung expansion (C)</p> Signup and view all the answers

    What is indicated by high compliance in the lungs?

    <p>Lungs expand easily and require less effort for inflation (C)</p> Signup and view all the answers

    What factor is NOT primarily related to lung compliance?

    <p>Airway resistance (A)</p> Signup and view all the answers

    What happens to airway resistance during exhalation?

    <p>Airway resistance increases as bronchioles diameter narrows (A)</p> Signup and view all the answers

    Which factor can lead to decreased lung compliance?

    <p>Presence of scar lung tissue (C)</p> Signup and view all the answers

    What is the primary effect of surface tension on lung elastic recoil?

    <p>It accounts for two-thirds of the elastic recoil (D)</p> Signup and view all the answers

    Which condition can cause increased airway resistance?

    <p>Obstruction or collapse of airways (C)</p> Signup and view all the answers

    How is the airflow through the airways primarily determined?

    <p>By the pressure difference divided by airway resistance (B)</p> Signup and view all the answers

    Why do healthy lungs exhibit high compliance?

    <p>Because of easily stretched elastic fibers and reduced surface tension (B)</p> Signup and view all the answers

    Flashcards

    Functions of respiratory system

    The respiratory system provides oxygen, eliminates carbon dioxide, regulates blood pH, produces speech sounds, and defends against microbes.

    Pulmonary ventilation

    The process of inhaling and exhaling air.

    External respiration

    Gas exchange between the lungs' alveoli and the capillaries.

    Respiratory mechanism

    Involves pressure and volume changes in the lungs during breathing.

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    Respiratory muscles

    Muscles that help inhale and exhale.

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    Pressure Change for Inhalation

    Air moves into the lungs when the air pressure inside the lungs is less than the air pressure in the atmosphere.

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    Pressure Change for Exhalation

    Air moves out of the lungs when the air pressure inside the lungs is greater than the air pressure in the atmosphere.

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    What happens to the diaphragm during inhalation?

    The diaphragm contracts and flattens.

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    What happens to the rib cage during inhalation?

    The rib cage moves upwards & outwards.

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    What happens to the diaphragm during exhalation?

    The diaphragm relaxes.

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    What happens to the rib cage during exhalation?

    The rib cage moves downwards and upwards.

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    Main muscle for inhalation

    The most important muscle of inhalation is the diaphragm, the dome-shaped skeletal muscle that forms the floor of the thoracic cavity.

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    What happens to the thoracic cavity during inhalation?

    Inhalation increases the vertical diameter of the thoracic cavity, primarily due to the diaphragm contracting and descending.

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    Diaphragm's role in quiet inhalation

    The diaphragm descends about 1 cm during quiet inhalation, creating a pressure difference of 1-3 mmHg. This allows for the inhalation of approximately 500 mL of air.

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    Diaphragm's role in forceful inhalation

    During strenuous breathing, the diaphragm descends 10 cm, generating a pressure difference of 100 mmHg. This enables inhalation of 2-3 liters of air.

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    External Intercostals and Thoracic Diameter

    Contraction of the external intercostal muscles elevates the ribs, increasing both the anteroposterior and lateral diameters of the chest cavity.

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    Accessory Muscles of Inspiration

    These muscles aid in forced inspiration during activities such as exercise, coughing, sneezing, and asthma.

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    Scalene Muscle Function

    Contraction of the scalene muscle enlarges the upper rib cage, increasing the thoracic cavity volume for inspiration.

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    Intrapleural Pressure During Inhalation

    Intrapleural pressure (pressure between the pleural layers) is always subatmospheric (lower than atmospheric pressure) during quiet inhalation.

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    Intrapleural Pressure Changes

    As the diaphragm and external intercostals contract and the thoracic cavity expands, intrapleural pressure decreases due to the increased volume of the pleural cavity.

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    What is intrapleural pressure?

    The pressure between the parietal and visceral pleurae, which is lower than atmospheric pressure due to surface tension. It's always negative, keeping the lungs inflated.

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    Alveolar pressure during inhalation

    The pressure inside the alveoli drops below atmospheric pressure when the lungs expand, causing air to flow in.

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    Active inhalation

    Involves muscle contraction, such as the diaphragm and intercostals, to expand the chest cavity.

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    Passive exhalation

    Doesn't require muscle contraction, instead relies on the elastic recoil of the lungs and chest wall.

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    Forces involved in exhalation

    Elastic recoil of chest wall and lungs, driven by stretched elastic fibers and surface tension of alveolar fluid.

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    Diaphragm during exhalation

    The diaphragm relaxes, moving upwards and decreasing the volume of the thoracic cavity.

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    Rib cage during exhalation

    The ribs are depressed, helping to reduce the volume of the thoracic cavity.

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    Factors affecting pulmonary ventilation

    Airflow and ease of breathing are affected by factors like airway resistance, lung compliance, and surface tension of the alveolar fluid.

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    Inspiratory Reserve Volume (IRV)

    The additional volume of air you can inhale after a normal breath, during a deep, maximal inspiration.

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    Expiratory Reserve Volume (ERV)

    The extra volume of air you can exhale after a normal breath, during a forceful expiration.

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    Vital Capacity (VC)

    The maximum volume of air you can move in and out of your lungs in one breath.

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    Residual Volume

    The amount of air that always remains in your lungs, even after a forceful exhalation. It cannot be directly measured.

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    Functional Residual Capacity (FRC)

    The amount of air left in your lungs after a normal exhalation.

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    Alveolar Fluid Surface Tension

    A force exerted by the thin layer of fluid lining the alveoli, pulling inwards due to the strong attraction between water molecules.

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    Surface Tension and Breathing

    Surface tension must be overcome during inhalation to expand the lungs, and it also contributes to lung recoil during exhalation.

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    Lung Compliance

    How easily the lungs and chest wall stretch during breathing.

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    Factors Affecting Lung Compliance

    Compliance is influenced by lung tissue elasticity and surface tension.

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    Decreased Lung Compliance

    Conditions like scarring, fluid in the lungs, or surfactant deficiency make it harder to breathe.

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    Airway Resistance

    The opposition to airflow through the airways, mainly due to the bronchioles.

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    Airway Diameter and Resistance

    Larger airway diameter leads to less resistance, while smaller diameter increases resistance.

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    Asthma and COPD

    These conditions increase airway resistance by narrowing or obstructing airways.

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    Tidal Volume (TV)

    The amount of air breathed in and out during normal, quiet breathing.

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    Lung Volumes and Capacities

    Different measures of air volume in the lungs, including tidal volume, vital capacity, and residual volume.

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    Study Notes

    Introduction to Respiratory Physiology

    • The respiratory system's function is to supply oxygen to the body and remove carbon dioxide.
    • Other functions include regulation of blood pH, phonation and defense against microbes.

    Subtopics and Learning Outcomes

    • The course covers the physiology of the respiratory system.
    • Students should be able to describe the functions of the respiratory system.
    • Understand gas and pressure changes during pulmonary ventilation.
    • Describe the mechanism of respiration.
    • Name the muscles involved.
    • Describe intrapleural and intraplumonic pressure.
    • Summarize factors influencing pulmonary ventilation.
    • Define lung volumes and capacities.

    Gas Exchange

    • Respiration has three stages:
      • Pulmonary ventilation (breathing): Inhalation and exhalation of air.
      • External respiration (pulmonary respiration): Exchange of gases between alveoli of the lungs and blood in pulmonary capillaries.
      • Internal respiration (tissue respiration): Exchange of gases between blood in systemic capillaries and tissue cells.

    Pressure Changes During Pulmonary Ventilation

    • Air flows from high to low pressure.
    • Air moves into the lungs when the pressure inside the lungs is lower than atmospheric pressure.
    • Air moves out of the lungs when the pressure inside the lungs is higher than atmospheric pressure.

    Mechanism of Respiration

    • Inhalation:
      • Internal intercostal muscles relax.
      • External intercostal muscles contract.
      • Rib cage moves upward and outwards.
      • Diaphragm contracts and flattens.
      • Thorax cavity volume increases.
      • Alveolar pressure decreases.
    • Exhalation:
      • Internal intercostal muscles contract.
      • External intercostal muscles relax.
      • Rib cage moves downward and inwards.
      • Diaphragm relaxes and arches up.
      • Thorax cavity volume decreases.
      • Alveolar pressure increases.
    • Air flows into lungs when pressure there is less that atmospheric pressure.
    • Air flows out of lungs when pressure there is higher than atmospheric pressure.

    Muscles of Respiration

    • Diaphragm: The primary muscle of inhalation; its contraction flattens the dome, increasing thoracic cavity volume.
    • External Intercostal muscles: Elevate ribs during inhalation, increasing the thoracic cavity's anteroposterior and lateral diameters.
    • Accessory muscles: Involved in forced breathing (e.g., exercise, coughing, sneezing) including scalenes, pectoralis major/minor, and sternocleidomastoid.

    Intrapleural Pressure

    • Pressure between the two pleural layers is subatmospheric (lower than atmospheric pressure).
    • During inhalation, the intrapleural pressure decreases.
    • The difference between the intra-alveolar pressure and intrapleural pressure is called transpulmonary pressure.

    Alveolar (Intrapulmonic) Pressure

    • Pressure inside the lungs.
    • During inhalation, alveolar pressure decreases.
    • Air moves into the lungs as pressure inside the lungs is lower.
    • For exhalation, the pressures are reversed.

    Active and Passive Processes of Breathing

    • Inhalation is usually an active process, involving muscle contractions to increase lung volume.
    • Exhalation is primarily a passive process, relying on elastic recoil of the lungs and chest wall, with minimal muscular effort in regular breathing.

    Factors Affecting Pulmonary Ventilation

    • Surface tension of Alveolar Fluid: This force tends to reduce alveolar size; surfactant reduces surface tension.
    • Compliance: How easily the lungs expand; high compliance means easier expansion.
    • Airway resistance: Resistance to airflow in airways. Increased airways resistance requires more pressure to produce the same airflow.

    Lung Volumes and Capacities

    • Tidal Volume (TV): Air inhaled and exhaled in a normal breath; approximately 500 mL.
    • Inspiratory Reserve Volume (IRV): Extra air that can be inhaled beyond a normal breath.
    • Expiratory Reserve Volume (ERV): Extra air that can be exhaled beyond a normal breath.
    • Residual Volume (RV): Air remaining in lungs after maximal exhalation (cannot be measured directly).
    • Vital Capacity (VC): Maximum volume of air that can be exhaled after maximum inhalation.
    • Inspiratory Capacity (IC): Maximum volume of air that can be inspired after a normal exhalation.
    • Functional Residual Capacity (FRC): Volume of air remaining in the lungs after normal exhalation.

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    Description

    This quiz covers the fundamental concepts of respiratory physiology, including the functions of the respiratory system, pulmonary ventilation, and gas exchange. Students will explore the mechanisms involved in respiration and factors that influence pulmonary ventilation.

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