Podcast
Questions and Answers
Which of the following is a key distinguishing feature of acute pain?
Which of the following is a key distinguishing feature of acute pain?
What type of pain is associated with damage to the nervous system?
What type of pain is associated with damage to the nervous system?
Which statement correctly relates to chronic pain?
Which statement correctly relates to chronic pain?
Which type of pain is characterized by its origin in the body's tissues?
Which type of pain is characterized by its origin in the body's tissues?
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What is one common non-pharmacological treatment option for managing pain?
What is one common non-pharmacological treatment option for managing pain?
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What characterizes nociceptive pain?
What characterizes nociceptive pain?
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Which type of pain is associated with tissue damage and involves immune cells promoting healing?
Which type of pain is associated with tissue damage and involves immune cells promoting healing?
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What is a common characteristic of maladaptive pain?
What is a common characteristic of maladaptive pain?
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Which of the following is NOT typically associated with the burden of chronic pain?
Which of the following is NOT typically associated with the burden of chronic pain?
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What type of pain is characterized by 'sharp' or 'throbbing' sensations and is usually well-localized?
What type of pain is characterized by 'sharp' or 'throbbing' sensations and is usually well-localized?
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Which of the following descriptions accurately describes neuropathic pain?
Which of the following descriptions accurately describes neuropathic pain?
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The concept of adaptive pain is best described as:
The concept of adaptive pain is best described as:
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Which of the following is a common consequence of chronic pain?
Which of the following is a common consequence of chronic pain?
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What is a characteristic descriptor of neuropathic pain?
What is a characteristic descriptor of neuropathic pain?
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Which of the following conditions is associated with nociplastic pain?
Which of the following conditions is associated with nociplastic pain?
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Which of the following best describes the nature of nociplastic pain?
Which of the following best describes the nature of nociplastic pain?
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What kind of pain does Ayaan Jessa experience based on the description?
What kind of pain does Ayaan Jessa experience based on the description?
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What likely contributed to Daphne Monta's symptoms?
What likely contributed to Daphne Monta's symptoms?
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What role does neuronal damage play in nociplastic pain?
What role does neuronal damage play in nociplastic pain?
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Which of the following is a common form of neuropathic pain?
Which of the following is a common form of neuropathic pain?
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In which demographic or condition is diabetic neuropathy typically found?
In which demographic or condition is diabetic neuropathy typically found?
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What type of pain may Carole Parkinson be experiencing, considering her symptoms of constant pain and burning sensations?
What type of pain may Carole Parkinson be experiencing, considering her symptoms of constant pain and burning sensations?
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What distinguishes cancer pain from non-cancer pain?
What distinguishes cancer pain from non-cancer pain?
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Which of the following is a common treatment goal for acute pain management?
Which of the following is a common treatment goal for acute pain management?
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What type of pain is characterized by having many different causes and may be either acute or chronic?
What type of pain is characterized by having many different causes and may be either acute or chronic?
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Which symptoms are indicative of chronic pain as opposed to acute pain?
Which symptoms are indicative of chronic pain as opposed to acute pain?
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What is a potential characteristic of cancer pain that is frequently differentiated from non-cancer pain?
What is a potential characteristic of cancer pain that is frequently differentiated from non-cancer pain?
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What type of pain is most commonly associated with conditions like chronic back pain?
What type of pain is most commonly associated with conditions like chronic back pain?
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Which of the following conditions could potentially lead to cancer pain due to nerve compression?
Which of the following conditions could potentially lead to cancer pain due to nerve compression?
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What is a requirement for a pharmacist working in pain management services?
What is a requirement for a pharmacist working in pain management services?
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Which of the following is essential for pharmacists involved in pain management?
Which of the following is essential for pharmacists involved in pain management?
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What must pain services have access to for expert advice?
What must pain services have access to for expert advice?
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What distinguishes a pharmacist acting as a 'practitioner with a special interest' in pain management?
What distinguishes a pharmacist acting as a 'practitioner with a special interest' in pain management?
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What is vital for centers that provide epidural or intrathecal drug delivery?
What is vital for centers that provide epidural or intrathecal drug delivery?
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Which class of medications includes gabapentin and pregabalin?
Which class of medications includes gabapentin and pregabalin?
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What is one of the main objectives of hospital pharmaceutical services?
What is one of the main objectives of hospital pharmaceutical services?
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Which of the following is a non-pharmacological self-care strategy for pain management?
Which of the following is a non-pharmacological self-care strategy for pain management?
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Who is NOT considered a member of the multidisciplinary team in pain management?
Who is NOT considered a member of the multidisciplinary team in pain management?
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Which of the following is classified as a corticosteroid?
Which of the following is classified as a corticosteroid?
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What is the role of pharmacotherapy in self-care pain management?
What is the role of pharmacotherapy in self-care pain management?
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What approach does acceptance commitment therapy typically emphasize?
What approach does acceptance commitment therapy typically emphasize?
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Which invasive technique is commonly used for pain management?
Which invasive technique is commonly used for pain management?
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Study Notes
Introduction to Pain
- Pain is not uniform; different types of pain exist.
- This lecture will classify pain, outline approaches to classifying pain, and describe the role of pharmacists in pain management.
- Key features distinguishing acute and chronic pain will be identified.
- Four types of pain, based on their underlying mechanism, will be explained.
Aims of the Lecture
- Outline different approaches to classifying pain
- Identify key features distinguishing between acute and chronic pain
- Explain four types of pain by their underlying mechanism (aetiology): nociceptive, inflammatory, neuropathic, and nociplastic
- Describe the physical and emotional impacts of living with pain
- Outline pharmacological and non-pharmacological pain treatment options
- Describe the pharmacist's role in pain management
Main Types of Pain Classification
- Not all pain is the same
- Key considerations include duration, etiology (mechanism), cause, location, (e.g., headache, visceral, musculoskeletal) and whether it's cancer-related or not
- Pain is classified into acute and chronic, and further subdivided into nociceptive, inflammatory, neuropathic, and nociplastic pain
Pain Classification by Duration
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Acute Pain:*
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Recent onset, usually short-lived
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Linked to clear tissue injury (e.g., injury, surgery, burn)
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Severity varies with the extent of injury
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Predictable time course
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Generally, responds well to treatment
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Chronic Pain:*
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Lasting more than 3 months
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Can occur after expected healing
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May have no discernible cause or pathological process
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Intensity might not correlate with tissue injury
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Time course is unpredictable
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Often difficult to treat
Burden of Chronic Pain
- Chronic pain can negatively impact quality of life
- Associated with depressive feelings
- Sleep disturbances
- Fatigue
- Impaired physical functioning
- Difficulty concentrating
- Increased time off work
- Reduced activity levels
Pain Classification by Aetiology
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Adaptive pain:* Has a function
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Nociceptive pain
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Inflammatory pain
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Non-adaptive pain:* (maladaptive, pathological)
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Neuropathic pain
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Nociplastic pain ((dys)functional pain)
Aetiology: Nociceptive Pain
- 'Good' pain, protective function
- Sensation from potentially tissue-damaging noxious stimuli
- Example scenario: a 5-year-old child burns their hand on a hot kettle
Aetiology: Inflammatory Pain
- Obvious tissue injury or illness
- Associated with tissue injury and immune cell infiltration
- Adaptive, protective function
- Descriptors: sharp, dull, aching, throbbing, well-localised, characteristic case study (Ayaan Jessa)
Aetiology: Neuropathic Pain
- Caused by damage to or disease of the sensory nervous system
- Tissue injury may not be immediately obvious
- Does not have a protective function
- Descriptors: burning, shooting, pins and needles, numbness, less well-localised
- This type of pain can be caused by certain conditions or medications (e.g., stroke, chemotherapy, certain viral infections)
Neuropathic Pain Scenarios
- Peripheral: Drugs (e.g., chemotherapy), amputation (phantom limb), infections (e.g., shingles), trigeminal neuralgia, diabetes
- Spinal: Spinal injury, MS
- Brain: Stroke, tumour
Case study: Daphne Monta
- 61-year-old woman with type 2 diabetes
- Experiences constant tingling and burning pain in both feet
- Pain interferes with daily activities and sleep.
Aetiology: Nociplastic Pain
- Substantial pain without noxious stimuli or minimal peripheral inflammatory pathology
- No neuronal damage or injury
- Abnormal function of the pain axis; related to central sensitization and nerve memory
- Associated with various conditions (e.g., fibromyalgia, IBS, tension-type headaches)
- Case study: Carole Parkinson (chronic widespread pain, pain in various locations, fatigue, sleep disturbances)
Cancer v Non-cancer Pain
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Cancer pain:*
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Often progressive
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Might be a combination of acute and chronic pain
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Can be related to nerve compression, chemotherapy, or disease progression
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Non-cancer pain:*
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Various underlying causes
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Can be acute or chronic
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Examples include fractures, appendicitis, chronic back pain, or arthritis
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May be mixed nociceptive and neuropathic
Cancer Pain Examples
- Uterine cervical cancer, breast cancer, bone metastases (spread of cancer to the bones), due to nerve compression, chemotherapy
Non-cancer Pain Examples
- Fracture, appendicitis, myocardial infarction (heart attack), chronic back pain, arthritis
Goals of Treatment
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Acute pain:*
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Patient comfort and satisfaction
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Earlier mobilization
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Reduced hospital stay
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Minimize stress response and neuroendocrine effects
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Minimize adverse effects on various systems (respiratory, cardiovascular, etc.)
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Chronic pain:*
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Improved function
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Pain management
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Reduction in healthcare utilization
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Greater understanding of ongoing pain
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Less fear associated with physical activity
Management Strategies
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Pharmacological:*
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Paracetamol
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NSAIDs and coxibs
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Opioids
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Local anaesthetics
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Ketamine
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Corticosteroids
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Antidepressants (tricyclics, serotonin-norepinephrine reuptake inhibitors)
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Anti-epileptics (gabapentin, pregabalin, carbamazepine)
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Non-pharmacological:*
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Self-care (heat/cold, activity and exercise, pacing activities, sleep hygiene)
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Cognitive behavioural therapy
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Acceptance commitment therapy
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Acupuncture
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Transcutaneous electrical nerve stimulation (TENS)
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Pain management programs
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Invasive devices (spinal cord stimulation, deep brain stimulation)
Members of the Multidisciplinary Team
- Doctors
- Nurses
- Pharmacists
- Physiotherapists
- Psychologists
- Occupational therapists
- Person with pain
Pharmacist's Evolving Role
- Hospital pharmaceutical services aim to ensure the preparation, assembly, efficient procurement, and safe storage and distribution of quality medicines, facilitating safe and efficient medicine use.
- Pharmacists are integral to the multidisciplinary team managing pain, possessing knowledge of medicines, interactions and appropriate therapies, offering advice and support.
Summary
- Pain classification is essential, with consideration of acute/chronic, cancer/non-cancer, nociceptive/neuropathic types.
- Pharmacists are crucial members of the pain management team.
- Treatment varies depending on the type of pain.
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Description
This quiz covers various aspects of pain, including its classification into acute and chronic types. Key features and underlying mechanisms of different pain types will be explored, alongside the role of pharmacists in managing pain. Learn about both pharmacological and non-pharmacological treatment options.