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Introduction to Oncology PHCL 477

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Questions and Answers

What is the definition of neoplasm?

Invasion of distant tissues or organs

An increase in the number of cells

An abnormal mass of tissue resulting from uncontrolled cell division (correct)

Abnormal size and shape of cells

Which term refers to the lack of differentiation in abnormal cells?

Dysplasia

Metastasis

Hyperplasia

Anaplasia (correct)

What is the characteristic feature of dysplasia?

Invasion of distant tissues or organs

Abnormal size and shape of cells (correct)

Uncontrolled cell division

Increase in number of cells

Which of the following best describes metastasis?

Invasion of distant tissues or organs (C) Signup and view all the answers

What is the primary characteristic of hyperplasia?

Increase in number of cells (A) Signup and view all the answers

Which term refers to the uncontrolled growth and spread of abnormal cells to distant organs?

Metastasis (B) Signup and view all the answers

Which term is synonymous to cancer?

Malignancy (B) Signup and view all the answers

Which type of tumor has atypical characteristics of tissue of origin and a fatal prognosis if untreated?

Carcinoma (A) Signup and view all the answers

What is the characteristic of malignant tumors related to growth?

Seldom have capsules, growth by infiltration (A) Signup and view all the answers

Which type of malignancy is associated with epithelial cells?

Carcinoma (D) Signup and view all the answers

What is the mutagenic agent that causes DNA damage, increased P53 expression, and G1 arrest for repair in normal cells?

Mutagenic agent A (B) Signup and view all the answers

What type of genes stimulate cell division in normal cells?

Proto-oncogenes (B) Signup and view all the answers

What does the loss of P53 function lead to in transformed cells?

Cell growth control (B) Signup and view all the answers

Which gene turns off cancer in normal cells?

BRCA 2 (B) Signup and view all the answers

What are the characteristic features of solid malignancies?

"Fibrous tissue" and "Fatty tissue" (B) Signup and view all the answers