Introduction to Oncology PHCL 477
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Questions and Answers

What is the definition of neoplasm?

  • Invasion of distant tissues or organs
  • An increase in the number of cells
  • An abnormal mass of tissue resulting from uncontrolled cell division (correct)
  • Abnormal size and shape of cells

Which term refers to the lack of differentiation in abnormal cells?

  • Dysplasia
  • Metastasis
  • Hyperplasia
  • Anaplasia (correct)

What is the characteristic feature of dysplasia?

  • Invasion of distant tissues or organs
  • Abnormal size and shape of cells (correct)
  • Uncontrolled cell division
  • Increase in number of cells

Which of the following best describes metastasis?

<p>Invasion of distant tissues or organs (C)</p> Signup and view all the answers

What is the primary characteristic of hyperplasia?

<p>Increase in number of cells (A)</p> Signup and view all the answers

Which term refers to the uncontrolled growth and spread of abnormal cells to distant organs?

<p>Metastasis (B)</p> Signup and view all the answers

Which term is synonymous to cancer?

<p>Malignancy (B)</p> Signup and view all the answers

Which type of tumor has atypical characteristics of tissue of origin and a fatal prognosis if untreated?

<p>Carcinoma (A)</p> Signup and view all the answers

What is the characteristic of malignant tumors related to growth?

<p>Seldom have capsules, growth by infiltration (A)</p> Signup and view all the answers

Which type of malignancy is associated with epithelial cells?

<p>Carcinoma (D)</p> Signup and view all the answers

What is the mutagenic agent that causes DNA damage, increased P53 expression, and G1 arrest for repair in normal cells?

<p>Mutagenic agent A (B)</p> Signup and view all the answers

What type of genes stimulate cell division in normal cells?

<p>Proto-oncogenes (B)</p> Signup and view all the answers

What does the loss of P53 function lead to in transformed cells?

<p>Cell growth control (B)</p> Signup and view all the answers

Which gene turns off cancer in normal cells?

<p>BRCA 2 (B)</p> Signup and view all the answers

What are the characteristic features of solid malignancies?

<p>&quot;Fibrous tissue&quot; and &quot;Fatty tissue&quot; (B)</p> Signup and view all the answers

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