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Questions and Answers
What happens when molecules in gas state are bombarded with high energy electrons?
What happens when molecules in gas state are bombarded with high energy electrons?
- They gain an electron and form a radical cation
- They break down into smaller molecules
- They lose an electron and form a molecular ion (M+) (correct)
- They remain unchanged
What does mass spectrometry provide information about?
What does mass spectrometry provide information about?
- Physical state of the molecule
- Isotopic composition of the molecule
- Chemical reactions of the molecule
- Exact molecular weight and molecular formula (correct)
What does the intensity of each signal in mass spectrometry represent?
What does the intensity of each signal in mass spectrometry represent?
- Molecular weight of the cations
- Relative abundance of the radicals
- Molecular weight of the radicals
- Relative abundance of the cations (correct)
What is a molecular ion (M+)?
What is a molecular ion (M+)?
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What is separated by magnetic deflection in mass spectrometry?
What is separated by magnetic deflection in mass spectrometry?
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Study Notes
Mass Spectrometry
- When molecules in a gas state are bombarded with high-energy electrons, they break into charged particles called ions.
- Mass spectrometry provides information about the mass-to-charge ratio of ions, which helps identify the structure of molecules.
Signal Intensity
- The intensity of each signal in mass spectrometry represents the abundance of ions with a specific mass-to-charge ratio.
Molecular Ion
- A molecular ion (M+) is a molecule that has lost or gained one or more electrons to form an ion with a single charge.
Ion Separation
- In mass spectrometry, ions are separated by magnetic deflection according to their mass-to-charge ratio.
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Description
This quiz covers the basic principles of mass spectrometry, focusing on the detection of molecular weight and the process of ionization and fragmentation of molecules. It is designed to test understanding of how mass spectrometry provides information about molecular formula and structural elucidation of drugs.
