Introduction to Hemostasis: Key Terms and Processes

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The 1st stage in coagulation - Blood vessels contract to seal the wound and platelet fill the open space by forming a platelet plug.


2nd phase of hemostasis - Enzymatic reaction of plasma coagulation factors results in the production of an insoluble fibrin clot.


Injury 🡪 constriction of blood vessels (to reduce blood flow) 🡪 platelet adherence (to blood vessel wall) 🡪 platelet aggregation (aggregate/ come in contact to one another) 🡪 formation of platelet plug GENERAL PROCESS OF HEMOSTASIS 1.

Blood vessel constriction

GENERAL PROCESS OF HEMOSTASIS 2. Formation of ________ plug


GENERAL PROCESS OF HEMOSTASIS 3. Interaction of damaged blood vessels, platelets, and coagulation ________


NORMAL HEMOSTATIC BALANCE - In the body, coagulation and fibrinolysis must be balanced. If there is too much coagulation hypercoagulable state ____________ (formation of clot)


HEMOSTASIS is the series of cellular and humoral system that balances flow of blood within the circulation- cessation of blood flow.


THROMBOSIS is the formation of ______ in a blood vessel.


COAGULATION is the sequential ______ by which multiple plasma enzymes, cofactors, and other related substances interact in sequence to form an insoluble fibrin clot.


FIBRINOGEN is a plasma ______- converted to fibrin at the end of the coagulation cascade. Fibrin is the active form of fibrinogen that serves as the 'glue' to stop bleeding.


Explore the fundamental concepts of hemostasis, including key terms and processes such as vasoconstriction, platelet adhesion, aggregation, and coagulation enzyme activation. Learn about the types of hemostasis and the components involved in maintaining normal hemostatic balance.

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