Lecture 1 Part 1

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Questions and Answers

What is the main focus of epidemiology?

  • Diagnosis and prognosis of diseases at the individual level
  • Treatment methods for individuals with diseases
  • Identification of effective medications for diseases
  • Study of diseases in populations (correct)

Which of the following best describes the term 'incidence rate'?

  • The ratio of new cases to the total population at risk during a specific time period (correct)
  • The number of total cases of a disease at a specific time
  • The percentage of individuals diagnosed with a disease over their lifetime
  • The overall prevalence of a disease in a population

What is the general goal of epidemiological studies?

  • To discover new medications for diseases
  • To reduce the burden of disease through prevention and control (correct)
  • To categorize diseases based on symptoms
  • To identify patients who are at high risk

Which question is NOT a key question guiding epidemiological research?

<p>What treatments are most effective for the disease? (A)</p> Signup and view all the answers

How is prevalence defined in epidemiology?

<p>Total number of diagnosed cases in a population at a specific time (C)</p> Signup and view all the answers

In the example provided for diabetes mellitus, what is the total population at risk?

<p>5,000 individuals in the town (D)</p> Signup and view all the answers

What does the term 'etiology' refer to in the context of epidemiology?

<p>The likely causes of a disease (B)</p> Signup and view all the answers

What is measured when calculating a proportion in epidemiology?

<p>A specific quantity compared to the whole (C)</p> Signup and view all the answers

What is the key difference between incidence and prevalence?

<p>Prevalence accounts for the duration of the disease. (C), Incidence reflects new cases over a period of time. (D)</p> Signup and view all the answers

How is prevalence calculated?

<p>Total cases present at a point in time divided by total population. (C)</p> Signup and view all the answers

If there are 200 cases of a disease in a population of 50,000, what is the point prevalence in cases per 1,000 people?

<p>4 cases per 1,000 people (C)</p> Signup and view all the answers

Which factors affect the prevalence of a disease?

<p>The number of cases and the duration of the disease. (A)</p> Signup and view all the answers

If a disease has a high incidence but low prevalence, what can be inferred?

<p>Most individuals recover quickly or die soon after infection. (A)</p> Signup and view all the answers

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Study Notes

Epidemiology Overview

  • Study of diseases in populations, focusing on collective rather than individual health.
  • Aims to determine diagnosis and prognosis at a population level.
  • Quantifies incidence (new cases) and prevalence (existing cases) of diseases.
  • Identifies possible causes and risk factors impacting disease development.
  • Aims to reduce disease burden through prevention, control, and public health policies.

Key Research Questions

  • Evaluates the association between exposure and disease development.
  • Investigates if any observed association is genuine or confounded by other factors.

Quantifying Disease

  • Ratio: Relationship between two quantities, e.g., 1:4 dilution (1 part reagent to 4 parts buffer).
  • Proportion: Specific type of ratio reflecting part of a whole, calculated as a/(a+b).

Incidence Rate

  • Formula: Incidence Rate = Number of new cases during a specified time period / Total population at risk during that period.
  • This rate quantifies the risk of developing a new case of disease within a defined timeframe.
  • Units expressed as new cases per population per time period (e.g., cases per people-year).

Incidence Example

  • In a town of 5,000 residents, 25 new diabetes cases were diagnosed over five years.
  • Calculation: (25 new cases) / (5,000 people x 5 years) = 0.001 cases/people-year, or 1 case per 1,000 people-year.

Prevalence

  • Represents the total number of cases (new and existing) of a disease at a specific point in time.
  • Formula: Prevalence = Number of cases present at a point in time / Total population at that time.
  • Example: 200 HIV cases in a city of 50,000 leads to a point prevalence of 0.004, or 4 cases per 1,000 people.

Distinction Between Incidence and Prevalence

  • Incidence: Measure of risk associated with disease development, impacted by the speed of new cases and duration of disease.
  • Prevalence: Reflects the burden of a disease within a population at a specific time, determined by incidence and duration.
  • Relationship:
    • Prevalence is influenced by the number of new cases and how long individuals live with the disease.
    • Prevalence ≈ incidence x duration of infection.

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