Podcast
Questions and Answers
Where does the synthesis of acetylcholine from choline occur?
Where does the synthesis of acetylcholine from choline occur?
- In the extraneuronal sites
- In the storage vesicles
- In the neurotransmitter release sites
- In the axoplasm (correct)
What process actively accumulates choline into the axoplasm of a neuron?
What process actively accumulates choline into the axoplasm of a neuron?
- High-affinity choline uptake process (correct)
- Cholinergic nerve terminal accumulation
- Acetylcholine metabolism
- Neurotransmitter release process
Where is acetylcholine actively accumulated after its synthesis?
Where is acetylcholine actively accumulated after its synthesis?
- Neuromuscular junction
- Extraneuronal sites
- Cholinergic neurons in CNS
- Storage vesicles (correct)
What triggers the release of acetylcholine as a neurotransmitter?
What triggers the release of acetylcholine as a neurotransmitter?
Which is NOT a site where acetylcholine serves as the neurotransmitter?
Which is NOT a site where acetylcholine serves as the neurotransmitter?
What is the primary function of cholinergic neurons in the CNS?
What is the primary function of cholinergic neurons in the CNS?
What is the role of peripheral sympathetic preganglionic nerves in relation to acetylcholine?
What is the role of peripheral sympathetic preganglionic nerves in relation to acetylcholine?
What happens to acetylcholine after it is synthesized in the axoplasm?
What happens to acetylcholine after it is synthesized in the axoplasm?
What is the primary function of choline uptake into the axoplasm?
What is the primary function of choline uptake into the axoplasm?
What enzyme is responsible for converting dopamine to norepinephrine in the sympathetic nerve terminals?
What enzyme is responsible for converting dopamine to norepinephrine in the sympathetic nerve terminals?
Where is norepinephrine retained until an action potential arrives at the sympathetic nerve terminal?
Where is norepinephrine retained until an action potential arrives at the sympathetic nerve terminal?
Which enzyme catalyzes the N-methylation of norepinephrine to form epinephrine in the adrenal medulla?
Which enzyme catalyzes the N-methylation of norepinephrine to form epinephrine in the adrenal medulla?
In which cellular component does the synthesis of epinephrine occur in the adrenal medulla?
In which cellular component does the synthesis of epinephrine occur in the adrenal medulla?
What percentage of catecholamines in the adrenal medulla is accounted for by epinephrine in the human adult?
What percentage of catecholamines in the adrenal medulla is accounted for by epinephrine in the human adult?
'Dopamine β-hydroxylase represents the terminal enzyme in the biosynthesis of CA in the postganglionic sympathetic neuron.' Which enzyme serves a similar role for acetylcholine biosynthesis?
'Dopamine β-hydroxylase represents the terminal enzyme in the biosynthesis of CA in the postganglionic sympathetic neuron.' Which enzyme serves a similar role for acetylcholine biosynthesis?
'NE and epinephrine (EP) coexist in the adrenal medulla.' Why does this coexistence occur?
'NE and epinephrine (EP) coexist in the adrenal medulla.' Why does this coexistence occur?
'Cytoplasmic EP is then accumulated by the storage granule in the chromaffin cell.' What is the purpose of this accumulation?
'Cytoplasmic EP is then accumulated by the storage granule in the chromaffin cell.' What is the purpose of this accumulation?
What is the primary neurotransmitter released by adrenergic nerves?
What is the primary neurotransmitter released by adrenergic nerves?
What is the role of acetylcoenzymeA in the synthesis of acetylcholine in cholinergic neurons?
What is the role of acetylcoenzymeA in the synthesis of acetylcholine in cholinergic neurons?
