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Questions and Answers
Where does the synthesis of acetylcholine from choline occur?
What process actively accumulates choline into the axoplasm of a neuron?
Where is acetylcholine actively accumulated after its synthesis?
What triggers the release of acetylcholine as a neurotransmitter?
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Which is NOT a site where acetylcholine serves as the neurotransmitter?
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What is the primary function of cholinergic neurons in the CNS?
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What is the role of peripheral sympathetic preganglionic nerves in relation to acetylcholine?
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What happens to acetylcholine after it is synthesized in the axoplasm?
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What is the primary function of choline uptake into the axoplasm?
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What enzyme is responsible for converting dopamine to norepinephrine in the sympathetic nerve terminals?
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Where is norepinephrine retained until an action potential arrives at the sympathetic nerve terminal?
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Which enzyme catalyzes the N-methylation of norepinephrine to form epinephrine in the adrenal medulla?
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In which cellular component does the synthesis of epinephrine occur in the adrenal medulla?
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What percentage of catecholamines in the adrenal medulla is accounted for by epinephrine in the human adult?
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'Dopamine β-hydroxylase represents the terminal enzyme in the biosynthesis of CA in the postganglionic sympathetic neuron.' Which enzyme serves a similar role for acetylcholine biosynthesis?
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'NE and epinephrine (EP) coexist in the adrenal medulla.' Why does this coexistence occur?
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'Cytoplasmic EP is then accumulated by the storage granule in the chromaffin cell.' What is the purpose of this accumulation?
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What is the primary neurotransmitter released by adrenergic nerves?
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What is the role of acetylcoenzymeA in the synthesis of acetylcholine in cholinergic neurons?
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