19 Questions
What is the role of the Pepeptide epitope shown in red?
Recognized by MHC class II molecules
Which cell type recognizes the native epitope on the external viral coat protein?
B cell
What happens when a virus is captured and presented by a dendritic cell?
Activated CD4 T cell
What is the term used to describe the process of linked B-cell and T-cell interaction?
Co-stimulation
How do B-cells 'see' antigens?
Immunoglobulin as B-cell receptor
What happens when an activated T cell recognizes its peptide on a B cell?
Delivery of signals promoting antibody production
Why can't T-cell receptors (TCRs) recognize free antigen like immunoglobulin can?
'Seeing' antigens differently
Which antigen receptors are expressed at the plasma membrane for B-cells?
Immunoglobulin
What do the majority of T-cells require for antigen recognition?
Peptide-binding groove of an MHC molecule
What part of the virus is recognized by the surface immunoglobulin on a B cell?
External viral coat protein
Which cell type becomes activated when a virus captured and presented by a dendritic cell?
CD4 T cell
What is the role of the Pepeptide epitope shown in red?
Recognized by CD4 T cells
How do B-cells 'see' antigens?
With distinct antigen receptors expressed at the plasma membrane
What happens when an activated T cell recognizes its peptide on a B cell?
Dendritic cell delivers various accessory signals to the B cell
What do memory B cells primarily contribute to in the secondary immune response?
Antibody production kinetics
Why can't T-cell receptors (TCRs) recognize free antigen like immunoglobulin can?
Distinct binding specificities of TCRs compared to immunoglobulins
"B‐cells and T‐cells 'see' antigen in fundamentally different ways" mainly because:
"T-cells use distinct antigen receptors at the plasma membrane, unlike B-cells."
"Majority of T-cells can only recognise antigen when presented within the peptide‐binding groove of an MHC molecule" suggests:
"MHC molecules are essential for T-cell recognition of antigens."
"The majority of T‐cells can only recognise antigen when presented within the peptide‐binding groove of an MHC molecule" implies that:
"T-cell recognition requires MHC presentation."
Learn about B-cell B-Lymphocytes, which are the basis of humoral immunity in humans. Discover their development, role in adaptive immunity, and final destination as plasma cells.
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