Introduction of B-cell B-Lymphocytes
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Questions and Answers

What is the role of the Pepeptide epitope shown in red?

  • Activates nonspecific T cells
  • Recognized by the surface immunoglobulin on a B cell
  • Promotes antibody production against the coat protein
  • Recognized by MHC class II molecules (correct)

    • Which cell type recognizes the native epitope on the external viral coat protein?

  • B cell (correct)
  • Nonspecific T cell
  • Dendritic cell
  • CD4 T cell

    • What happens when a virus is captured and presented by a dendritic cell?

  • Activated CD4 T cell (correct)
  • No immune response
  • Antibody production by B cells
  • Activated nonspecific T cells

    • What is the term used to describe the process of linked B-cell and T-cell interaction?

    <p>Co-stimulation</p> Signup and view all the answers

    How do B-cells 'see' antigens?

    <p>Immunoglobulin as B-cell receptor</p> Signup and view all the answers

    What happens when an activated T cell recognizes its peptide on a B cell?

    <p>Delivery of signals promoting antibody production</p> Signup and view all the answers

    Why can't T-cell receptors (TCRs) recognize free antigen like immunoglobulin can?

    <p>'Seeing' antigens differently</p> Signup and view all the answers

    Which antigen receptors are expressed at the plasma membrane for B-cells?

    <p>Immunoglobulin</p> Signup and view all the answers

    What do the majority of T-cells require for antigen recognition?

    <p>Peptide-binding groove of an MHC molecule</p> Signup and view all the answers

    What part of the virus is recognized by the surface immunoglobulin on a B cell?

    <p>External viral coat protein</p> Signup and view all the answers

    Which cell type becomes activated when a virus captured and presented by a dendritic cell?

    <p>CD4 T cell</p> Signup and view all the answers

    What is the role of the Pepeptide epitope shown in red?

    <p>Recognized by CD4 T cells</p> Signup and view all the answers

    How do B-cells 'see' antigens?

    <p>With distinct antigen receptors expressed at the plasma membrane</p> Signup and view all the answers

    What happens when an activated T cell recognizes its peptide on a B cell?

    <p>Dendritic cell delivers various accessory signals to the B cell</p> Signup and view all the answers

    What do memory B cells primarily contribute to in the secondary immune response?

    <p>Antibody production kinetics</p> Signup and view all the answers

    Why can't T-cell receptors (TCRs) recognize free antigen like immunoglobulin can?

    <p>Distinct binding specificities of TCRs compared to immunoglobulins</p> Signup and view all the answers

    "B‐cells and T‐cells 'see' antigen in fundamentally different ways" mainly because:

    <p>&quot;T-cells use distinct antigen receptors at the plasma membrane, unlike B-cells.&quot;</p> Signup and view all the answers

    "Majority of T-cells can only recognise antigen when presented within the peptide‐binding groove of an MHC molecule" suggests:

    <p>&quot;MHC molecules are essential for T-cell recognition of antigens.&quot;</p> Signup and view all the answers

    "The majority of T‐cells can only recognise antigen when presented within the peptide‐binding groove of an MHC molecule" implies that:

    <p>&quot;T-cell recognition requires MHC presentation.&quot;</p> Signup and view all the answers

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