Introduction of B-cell B-Lymphocytes
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Questions and Answers

What is the role of the Pepeptide epitope shown in red?

  • Activates nonspecific T cells
  • Recognized by the surface immunoglobulin on a B cell
  • Promotes antibody production against the coat protein
  • Recognized by MHC class II molecules (correct)

Which cell type recognizes the native epitope on the external viral coat protein?

  • B cell (correct)
  • Nonspecific T cell
  • Dendritic cell
  • CD4 T cell

What happens when a virus is captured and presented by a dendritic cell?

  • Activated CD4 T cell (correct)
  • No immune response
  • Antibody production by B cells
  • Activated nonspecific T cells

What is the term used to describe the process of linked B-cell and T-cell interaction?

<p>Co-stimulation (C)</p> Signup and view all the answers

How do B-cells 'see' antigens?

<p>Immunoglobulin as B-cell receptor (A)</p> Signup and view all the answers

What happens when an activated T cell recognizes its peptide on a B cell?

<p>Delivery of signals promoting antibody production (B)</p> Signup and view all the answers

Why can't T-cell receptors (TCRs) recognize free antigen like immunoglobulin can?

<p>'Seeing' antigens differently (D)</p> Signup and view all the answers

Which antigen receptors are expressed at the plasma membrane for B-cells?

<p>Immunoglobulin (D)</p> Signup and view all the answers

What do the majority of T-cells require for antigen recognition?

<p>Peptide-binding groove of an MHC molecule (C)</p> Signup and view all the answers

What part of the virus is recognized by the surface immunoglobulin on a B cell?

<p>External viral coat protein (C)</p> Signup and view all the answers

Which cell type becomes activated when a virus captured and presented by a dendritic cell?

<p>CD4 T cell (D)</p> Signup and view all the answers

What is the role of the Pepeptide epitope shown in red?

<p>Recognized by CD4 T cells (B)</p> Signup and view all the answers

How do B-cells 'see' antigens?

<p>With distinct antigen receptors expressed at the plasma membrane (C)</p> Signup and view all the answers

What happens when an activated T cell recognizes its peptide on a B cell?

<p>Dendritic cell delivers various accessory signals to the B cell (C)</p> Signup and view all the answers

What do memory B cells primarily contribute to in the secondary immune response?

<p>Antibody production kinetics (D)</p> Signup and view all the answers

Why can't T-cell receptors (TCRs) recognize free antigen like immunoglobulin can?

<p>Distinct binding specificities of TCRs compared to immunoglobulins (B)</p> Signup and view all the answers

"B‐cells and T‐cells 'see' antigen in fundamentally different ways" mainly because:

<p>&quot;T-cells use distinct antigen receptors at the plasma membrane, unlike B-cells.&quot; (B)</p> Signup and view all the answers

"Majority of T-cells can only recognise antigen when presented within the peptide‐binding groove of an MHC molecule" suggests:

<p>&quot;MHC molecules are essential for T-cell recognition of antigens.&quot; (D)</p> Signup and view all the answers

"The majority of T‐cells can only recognise antigen when presented within the peptide‐binding groove of an MHC molecule" implies that:

<p>&quot;T-cell recognition requires MHC presentation.&quot; (D)</p> Signup and view all the answers

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