30 Questions
Which of the following is NOT a common symptom of asthma?
Mucus production
How can a presumptive diagnosis of asthma be made?
Based on a compatible history of recurrent wheezing
What should be done to confirm the diagnosis of asthma in all but the mildest cases?
Perform pulmonary function testing
What percentage of patients with a physician diagnosis of asthma do not meet the criteria for the diagnosis?
More than one-third
Which of the following is a common symptom in patients with asthma?
Frequent coughing
What is one key difference between exercise-induced symptoms and cardiac sources of dyspnea in patients with asthma?
Exercise symptoms tend to resolve more slowly
What is one factor that may trigger symptoms in allergen-sensitized patients with asthma?
Exposure to cold air
What is one possible indicator of reversible airways disease in patients with asthma?
Decreased peak expiratory flow rate
Which class of medications is known as long-acting muscarinic antagonists (LAMAs)?
Anticholinergics
What is the safety concern associated with higher doses of anticholinergic medications?
Urinary retention
Why is theophylline rarely used for asthma treatment?
All of the above
What is the recommended use of corticosteroids in asthma treatment?
As first-line therapy for all forms of persistent asthma
Which of the following is an approximate indicator of eosinophilic inflammation in the airways?
Exhaled Nitric Oxide Fraction (FeNO)
Which of the following levels of FeNO in untreated patients are indicative of eosinophilic inflammation?
35-40 ppb
Which of the following is true about the use of sputum analysis in severe asthma?
It helps characterize type 2 and non-type 2 inflammation
Which of the following is a goal of asthma therapy in terms of achieving control of symptoms and reducing risk?
Reducing triggers
Which of the following is true about intramuscular corticosteroids for asthma control?
They are associated with reduced side effects compared to intermittent bursts of systemic corticosteroids.
What are some side effects associated with chronic administration of systemic corticosteroids?
Diabetes, osteoporosis, cataracts, and glaucoma
What are some local effects of inhaled corticosteroids (ICS)?
Thrush and hoarseness
Which of the following is true about leukotriene modifiers for asthma?
They are moderately effective in asthma and can be used in patients with concomitant allergic rhinitis.
Which of the following is true about the dosing of Anti-IgE?
It is dosed based on body weight and circulating IgE
What is the maximum dose of Anti-IgE in the United States?
300 mg every 2 weeks
Which patients have the greatest response to Anti-IgE?
Patients with a body weight ≤150 kg
What is the incidence of anaphylaxis in patients receiving Anti-IgE?
0.2%
Which IL-5 active drug binds to the IL-5 receptor?
Benralizumab
What is the effect of IL-5 active drugs on circulating eosinophils?
They rapidly reduce circulating eosinophils
Which of the following is true about the use of long-acting beta-agonists (LABAs) in the treatment of asthma?
LABAs are usually used in combination with inhaled corticosteroids (ICS).
Which of the following is a safety concern associated with higher doses of beta-agonists?
Type B (nonhypoxic) lactic acidosis
Which of the following is a goal of asthma therapy in terms of achieving control of symptoms and reducing risk?
All of the above
Which of the following is true about the use of bronchodilators in the treatment of asthma?
Bronchodilators can be used to provide relief of bronchospasm or reduce bronchospasm anticipated in response to exercise or other stimuli.
Test your knowledge on the safety and efficacy of intramuscular corticosteroids for asthma control. Learn about the potential side effects and risks associated with chronic administration.
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