Intramuscular Corticosteroids for Asthma Control
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Questions and Answers

Which of the following is NOT a common symptom of asthma?

  • Wheezing
  • Mucus production (correct)
  • Shortness of breath
  • Chest tightness

    • How can a presumptive diagnosis of asthma be made?

  • Based on a compatible history of recurrent wheezing (correct)
  • Based on a history of shortness of breath
  • Based on a history of chest tightness
  • Based on a history of cough

    • What should be done to confirm the diagnosis of asthma in all but the mildest cases?

  • Perform a therapeutic trial of low-dose inhaled corticosteroid (ICS)
  • Perform a trial of tapering medications
  • Perform a trial of allergen avoidance
  • Perform pulmonary function testing (correct)

    • What percentage of patients with a physician diagnosis of asthma do not meet the criteria for the diagnosis?

    <p>More than one-third</p> Signup and view all the answers

    Which of the following is a common symptom in patients with asthma?

    <p>Frequent coughing</p> Signup and view all the answers

    What is one key difference between exercise-induced symptoms and cardiac sources of dyspnea in patients with asthma?

    <p>Exercise symptoms tend to resolve more slowly</p> Signup and view all the answers

    What is one factor that may trigger symptoms in allergen-sensitized patients with asthma?

    <p>Exposure to cold air</p> Signup and view all the answers

    What is one possible indicator of reversible airways disease in patients with asthma?

    <p>Decreased peak expiratory flow rate</p> Signup and view all the answers

    Which class of medications is known as long-acting muscarinic antagonists (LAMAs)?

    <p>Anticholinergics</p> Signup and view all the answers

    What is the safety concern associated with higher doses of anticholinergic medications?

    <p>Urinary retention</p> Signup and view all the answers

    Why is theophylline rarely used for asthma treatment?

    <p>All of the above</p> Signup and view all the answers

    What is the recommended use of corticosteroids in asthma treatment?

    <p>As first-line therapy for all forms of persistent asthma</p> Signup and view all the answers

    Which of the following is an approximate indicator of eosinophilic inflammation in the airways?

    <p>Exhaled Nitric Oxide Fraction (FeNO)</p> Signup and view all the answers

    Which of the following levels of FeNO in untreated patients are indicative of eosinophilic inflammation?

    <blockquote> <p>35-40 ppb</p> </blockquote> Signup and view all the answers

    Which of the following is true about the use of sputum analysis in severe asthma?

    <p>It helps characterize type 2 and non-type 2 inflammation</p> Signup and view all the answers

    Which of the following is a goal of asthma therapy in terms of achieving control of symptoms and reducing risk?

    <p>Reducing triggers</p> Signup and view all the answers

    Which of the following is true about intramuscular corticosteroids for asthma control?

    <p>They are associated with reduced side effects compared to intermittent bursts of systemic corticosteroids.</p> Signup and view all the answers

    What are some side effects associated with chronic administration of systemic corticosteroids?

    <p>Diabetes, osteoporosis, cataracts, and glaucoma</p> Signup and view all the answers

    What are some local effects of inhaled corticosteroids (ICS)?

    <p>Thrush and hoarseness</p> Signup and view all the answers

    Which of the following is true about leukotriene modifiers for asthma?

    <p>They are moderately effective in asthma and can be used in patients with concomitant allergic rhinitis.</p> Signup and view all the answers

    Which of the following is true about the dosing of Anti-IgE?

    <p>It is dosed based on body weight and circulating IgE</p> Signup and view all the answers

    What is the maximum dose of Anti-IgE in the United States?

    <p>300 mg every 2 weeks</p> Signup and view all the answers

    Which patients have the greatest response to Anti-IgE?

    <p>Patients with a body weight ≤150 kg</p> Signup and view all the answers

    What is the incidence of anaphylaxis in patients receiving Anti-IgE?

    <p>0.2%</p> Signup and view all the answers

    Which IL-5 active drug binds to the IL-5 receptor?

    <p>Benralizumab</p> Signup and view all the answers

    What is the effect of IL-5 active drugs on circulating eosinophils?

    <p>They rapidly reduce circulating eosinophils</p> Signup and view all the answers

    Which of the following is true about the use of long-acting beta-agonists (LABAs) in the treatment of asthma?

    <p>LABAs are usually used in combination with inhaled corticosteroids (ICS).</p> Signup and view all the answers

    Which of the following is a safety concern associated with higher doses of beta-agonists?

    <p>Type B (nonhypoxic) lactic acidosis</p> Signup and view all the answers

    Which of the following is a goal of asthma therapy in terms of achieving control of symptoms and reducing risk?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is true about the use of bronchodilators in the treatment of asthma?

    <p>Bronchodilators can be used to provide relief of bronchospasm or reduce bronchospasm anticipated in response to exercise or other stimuli.</p> Signup and view all the answers

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