Podcast
Questions and Answers
What is the role of integrins in cardiac function?
What is the role of integrins in cardiac function?
- Mediate cell-cell interactions
- Activate downstream signaling pathways
- Bind to collagen (correct)
- Form focal adhesions
Where do subsarcolemmal mitochondria (SSM) localize in cardiac muscle?
Where do subsarcolemmal mitochondria (SSM) localize in cardiac muscle?
- Between muscle fibers
- Adjacent to the cell membrane (correct)
- Around the nucleus
- At the center of the muscle cells
Which protein plays a role in mechanotransduction at adherent junctions?
Which protein plays a role in mechanotransduction at adherent junctions?
- Focal adhesions
- Cadherins (correct)
- Integrins
- Desmin
In what cellular component do intermediates filaments like Desmin localize in cardiac muscle?
In what cellular component do intermediates filaments like Desmin localize in cardiac muscle?
Which integrin binds to Fibronectin in the context of cardiac function?
Which integrin binds to Fibronectin in the context of cardiac function?
What is the main role of focal adhesions in mechanotransduction?
What is the main role of focal adhesions in mechanotransduction?
What is the main function of Desmin in cardiomyocytes?
What is the main function of Desmin in cardiomyocytes?
Where is Desmin mainly localized within cardiomyocytes?
Where is Desmin mainly localized within cardiomyocytes?
What is the function of Integrins in cell-matrix interaction in cardiomyocytes?
What is the function of Integrins in cell-matrix interaction in cardiomyocytes?
Which cytoskeleton protein has a slow dynamic compared to other fibers?
Which cytoskeleton protein has a slow dynamic compared to other fibers?
What is the primary role of Intermediate filaments in cardiomyocytes?
What is the primary role of Intermediate filaments in cardiomyocytes?
What is the impact of Desmin dysfunction on cardiac muscle function?
What is the impact of Desmin dysfunction on cardiac muscle function?
What is the primary role of cardiac fibroblasts?
What is the primary role of cardiac fibroblasts?
What triggers cytoskeletal remodeling in cardiac fibroblasts?
What triggers cytoskeletal remodeling in cardiac fibroblasts?
Which signaling pathways regulate cytoskeletal dynamics and fibroblast function in response to mechanical activation?
Which signaling pathways regulate cytoskeletal dynamics and fibroblast function in response to mechanical activation?
What are ciliopathies?
What are ciliopathies?
What is the role of desmin in cardiac muscle?
What is the role of desmin in cardiac muscle?
How do cytoskeletal abnormalities contribute to hypertension?
How do cytoskeletal abnormalities contribute to hypertension?
