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Questions and Answers
What is the primary role of the dermal papillae in the skin?
What is the primary role of the dermal papillae in the skin?
How does the thickness of the papillary layer differ between thin and thick skin?
How does the thickness of the papillary layer differ between thin and thick skin?
What are Langer’s lines associated with?
What are Langer’s lines associated with?
What type of connective tissue predominates in the reticular layer of the dermis?
What type of connective tissue predominates in the reticular layer of the dermis?
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What is the effect of making skin incisions parallel to Langer’s lines?
What is the effect of making skin incisions parallel to Langer’s lines?
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What is the primary function of sebaceous glands?
What is the primary function of sebaceous glands?
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Which type of sweat gland is most abundant in thick skin?
Which type of sweat gland is most abundant in thick skin?
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What type of secretion is produced by eccrine sweat glands?
What type of secretion is produced by eccrine sweat glands?
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Where are apocrine sweat glands primarily located?
Where are apocrine sweat glands primarily located?
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What type of cells line the secretory portion of apocrine sweat glands?
What type of cells line the secretory portion of apocrine sweat glands?
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During which physiological period does sebaceous gland activity increase?
During which physiological period does sebaceous gland activity increase?
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How does the secretion from apocrine sweat glands acquire its distinctive odor?
How does the secretion from apocrine sweat glands acquire its distinctive odor?
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What is the mechanism of secretion for both eccrine and apocrine sweat glands?
What is the mechanism of secretion for both eccrine and apocrine sweat glands?
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What is the primary material that makes up the hair shaft?
What is the primary material that makes up the hair shaft?
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Which layer of the hair is the outermost one?
Which layer of the hair is the outermost one?
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What connects the external root sheath to the stratum basale?
What connects the external root sheath to the stratum basale?
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How many concentric zones are identified in the structure of the hair shaft?
How many concentric zones are identified in the structure of the hair shaft?
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What is the composition of Henle’s layer in the internal root sheath?
What is the composition of Henle’s layer in the internal root sheath?
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Which layer of the hair provides a hard, shingle-like outer covering?
Which layer of the hair provides a hard, shingle-like outer covering?
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What type of cells give color to the hair?
What type of cells give color to the hair?
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Which structure is located closest to the hair shaft?
Which structure is located closest to the hair shaft?
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What is the primary function of keratinocytes in the epidermis?
What is the primary function of keratinocytes in the epidermis?
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In which layer of the skin is the stratum lucidum found?
In which layer of the skin is the stratum lucidum found?
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What is the main characteristic of the cells in the stratum corneum?
What is the main characteristic of the cells in the stratum corneum?
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Which type of cell is primarily responsible for the synthesis of melanin?
Which type of cell is primarily responsible for the synthesis of melanin?
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How long does it typically take for the stratum corneum to regenerate in healthy skin?
How long does it typically take for the stratum corneum to regenerate in healthy skin?
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Which layer of the epidermis does NOT have visible nuclei in its cells?
Which layer of the epidermis does NOT have visible nuclei in its cells?
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What happens to the epidermal turnover rate in diseases like psoriasis?
What happens to the epidermal turnover rate in diseases like psoriasis?
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Where are melanocytes located in the epidermis?
Where are melanocytes located in the epidermis?
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What is the primary function of eccrine sweat glands?
What is the primary function of eccrine sweat glands?
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What distinguishes apocrine sweat glands from eccrine sweat glands?
What distinguishes apocrine sweat glands from eccrine sweat glands?
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What is a characteristic feature of cystic fibrosis related to sweat glands?
What is a characteristic feature of cystic fibrosis related to sweat glands?
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Which part of the hair follicle is responsible for hair production?
Which part of the hair follicle is responsible for hair production?
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How does aging affect hair growth in both males and females?
How does aging affect hair growth in both males and females?
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Which component of the hair follicle connects it to the dermis?
Which component of the hair follicle connects it to the dermis?
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What is the visible part of the hair that protrudes from the skin called?
What is the visible part of the hair that protrudes from the skin called?
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What causes alopecia areata?
What causes alopecia areata?
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What is the primary composition of nails?
What is the primary composition of nails?
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Which layer of the hair follicle is directly involved in the growth of hair?
Which layer of the hair follicle is directly involved in the growth of hair?
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What structure is referred to as the 'lunula' in nails?
What structure is referred to as the 'lunula' in nails?
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Which of the following is NOT a layer of the epidermis?
Which of the following is NOT a layer of the epidermis?
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Which type of cells predominates in the epidermis?
Which type of cells predominates in the epidermis?
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What is the primary role of the hyponychium in nail anatomy?
What is the primary role of the hyponychium in nail anatomy?
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Which layer of the dermis is characterized as being superficial?
Which layer of the dermis is characterized as being superficial?
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What is the function of melanocytes in the epidermis?
What is the function of melanocytes in the epidermis?
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Study Notes
Integumentary System
- Skin (cutis, integument) forms the body's outermost covering and is the largest organ.
- Skin has two main layers: epidermis and dermis.
- The epidermis, the outer layer, is stratified squamous keratinized epithelium. It is avascular, receiving nutrition by diffusion from the dermis.
- The dermis, the deeper layer, is connective tissue, vascular, and contains collagen and elastic fibers. It has a superficial papillary layer and a deeper reticular layer.
- The hypodermis lies deep to the dermis and contains adipose tissue, equivalent to subcutaneous fascia.
- The epidermis is composed of several layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum (only in thick skin) and stratum corneum.
- Keratinocytes are the majority cell type in the epidermis responsible for keratin production; Keratinization is the process of transforming living cells into dead cells filled with keratin.
- Other specialized cells present in the epidermis include melanocytes (melanin production), Langerhans' cells (immune function), and Merkel cells (sensory function).
- Skin acts as a sensory organ, with nerve endings detecting pressure, touch, temperature, etc.
- Appendages of skin include hair, nails, and glands (sebaceous, sweat).
- The dermal ridges create unique patterns on the skin surface, called dermatoglyphics or fingerprints. This is unique to each individual.
- Skin performs important functions like thermoregulation, protection, sensation, and excretion.
- The epidermis has specific layers which are designed for different functions like barrier against entry of external substance.
- There are different types of sweat glands which have distinctive function (eccrine and apocrine).
- Hair follicles contain hair shaft and root, with papilla at the base. Hair provides insulation, and protection. Hair has three main layers: cuticle, cortex, and medulla.
- Nails are hard keratin plates over the nail beds.
- The dermis, by location, orientation, and composition of collagen and elastic fibers, plays a crucial role in providing flexibility.
- Nerves are crucial since they allow sense interpretation from skin.
Nerve Supply
- Sensory nerves carry sensation from free nerve endings, Meissner's corpuscles, Pacinian corpuscles, and Ruffini endings; these are involved in temperature, pain, touch, pressure.
- Enclosed nerve endings form the corpuscles.
- Free nerve endings can sense touch, pressure and temperature, while corpuscles are specific to detect more nuanced sensations. Skin nerves end directly within the epidermis.
Appendages
- Sebaceous glands produce sebum, a lipid substance that lubricates the skin and hair; this is associated with a hair follicle in a pilosebaceous complex
- Apocrine sweat glands are present in the armpits and genital areas, and secrete a viscous fluid that can smell; the secretion is often linked to emotional or nervous stimuli.
- Eccrine sweat glands are distributed throughout the body and secrete a watery sweat for thermoregulation.
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Description
Explore the structure and function of the integumentary system, focusing on the skin's layers, including the epidermis and dermis. Learn about the cellular composition, such as keratinocytes, and the processes involved in skin health and maintenance.