Insulin Types and Administration Quiz
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Questions and Answers

What is the onset time of Humulin R U-100 regular insulin?

  • 30 minutes (correct)
  • 12-20 minutes
  • 1.5 hours
  • 2.5-3 hours
  • How long does the duration of action last for Afrezza (inhalation) regular insulin?

  • 2.5-3 hours (correct)
  • 21 hours
  • 8 hours
  • 12-24 hours
  • What is the difference in the duration of action between Humulin R U-100 regular insulin and Humulin R U-500 concentrated regular insulin?

  • Humulin R U-500 lasts 3 hours longer
  • Humulin R U-100 lasts 3 hours longer
  • Humulin R U-500 lasts 13 hours longer (correct)
  • Humulin R U-100 lasts 13 hours longer
  • How often is Humulin N intermediate acting insulin administered?

    <p>Twice daily (D)</p> Signup and view all the answers

    Which type of insulin is recommended for injecting 30 minutes prior to a meal?

    <p>Humulin R U-100 (regular insulin) (D)</p> Signup and view all the answers

    What is the onset time for Humulin N intermediate acting insulin?

    <p>1.5 hours (B)</p> Signup and view all the answers

    Based on the information provided, what is the primary difference between Humulin R U-100 and Humulin R U-500?

    <p>Humulin R U-500 has a much longer duration of action. (C)</p> Signup and view all the answers

    What is the recommended time to administer Afrezza (inhalation) insulin?

    <p>12-20 minutes prior to meals (C)</p> Signup and view all the answers

    Which insulin type is most suitable for achieving 24 hours of basal insulin coverage?

    <p>Humulin N (intermediate acting insulin) (D)</p> Signup and view all the answers

    Which of these insulin types is most likely to be prescribed for a patient who requires a quick-acting insulin for managing post-meal blood sugar spikes?

    <p>Afrezza (inhalation) (D)</p> Signup and view all the answers

    Which insulin type requires twice daily injections to achieve a 24 hours basal insulin coverage?

    <p>Novolin N (B)</p> Signup and view all the answers

    Which insulin type has a mean duration of ~21 hours?

    <p>Humalin U-500 (D)</p> Signup and view all the answers

    Which insulin types are generally administered once daily but can be adjusted to twice daily for some patients?

    <p>Lantus (Insulin glargine) and Basaglar (Insulin glargine) (B)</p> Signup and view all the answers

    In general, for most patients, administering Novolin N twice daily is necessary to achieve what?

    <p>To achieve 24 hours basal insulin coverage (B)</p> Signup and view all the answers

    Administering Humulin U-500 twice daily is recommended to align with what?

    <p>The individual's glucose coverage needs (B)</p> Signup and view all the answers

    How long does the duration of the insulin action last for Novolin N?

    <p>12-24 hours (C)</p> Signup and view all the answers

    What is the recommended administration time for Novolin N?

    <p>30 minutes before a meal (C)</p> Signup and view all the answers

    What is the primary reason for checking glucose levels before administering insulin?

    <p>To prevent insulin stacking (C)</p> Signup and view all the answers

    What is the relationship between twice daily administration and the effects of Lantus or Basaglar?

    <p>It may provide benefit for some patients. (A)</p> Signup and view all the answers

    Which of the following statements about Novolin N is correct?

    <p>It should be administered 30 minutes before a meal to ensure more consistent blood sugar control. (B)</p> Signup and view all the answers

    Which insulin type would be most appropriate for a patient who needs to take their insulin right before or after a meal, but needs the insulin to work quickly?

    <p>Rapid acting insulin (C)</p> Signup and view all the answers

    Which insulin(s) should be administered subcutaneously into the abdomen, upper arm, thigh, or buttocks?

    <p>All insulin types listed in the content (C)</p> Signup and view all the answers

    Which insulin has the shortest onset time of action?

    <p>Fiasp (C)</p> Signup and view all the answers

    Which insulin has the longest duration of action?

    <p>All insulins have the same duration of action (D)</p> Signup and view all the answers

    A patient is experiencing a sudden spike in blood sugar levels after a meal. Which insulin is the best option for this situation?

    <p>Fiasp (B)</p> Signup and view all the answers

    Which insulin requires a dosage adjustment based on the time of administration relative to a meal?

    <p>NovoLog (B)</p> Signup and view all the answers

    What unique characteristic of Fiasp allows for faster absorption?

    <p>It is formulated with niacinamide (B)</p> Signup and view all the answers

    Which insulin can be taken up to 20 minutes after the start of a meal?

    <p>Fiasp and Lyumjev (A)</p> Signup and view all the answers

    A patient needs an insulin with a longer duration of action for overnight management. Which insulin would be the BEST choice for this patient?

    <p>None of the listed insulins would be appropriate for this patient (A)</p> Signup and view all the answers

    Considering a patient's need for mealtime insulin, which of the following is TRUE about Lyumjev?

    <p>Lyumjev can be taken either immediately before or up to 20 minutes after a meal, making it versatile for mealtime management (D)</p> Signup and view all the answers

    Which insulin type, based on its administration guidelines, would be the most suitable option for a patient who frequently forgets to take their insulin before meals?

    <p>Fiasp (C)</p> Signup and view all the answers

    A patient needs a rapid-acting insulin that can be administered 15 minutes before a meal but also provides flexibility to be taken immediately after eating. Which insulin type would be the most suitable choice in this scenario?

    <p>Humalog (A), Admelog (B)</p> Signup and view all the answers

    A patient is experiencing a sudden, unexpected spike in blood sugar levels following a meal. Which insulin type, based on its onset time, would be the most appropriate to address this situation quickly?

    <p>Fiasp (B)</p> Signup and view all the answers

    From the provided list, which insulin type(s) would be considered the most appropriate for a patient aiming to achieve a rapid reduction in blood sugar levels following a meal, thus minimizing the risk of postprandial hyperglycemia?

    <p>Fiasp (A), Lyumjev (C)</p> Signup and view all the answers

    A patient needs to carefully manage their postprandial blood sugar levels and prefers a rapid-acting insulin that offers some flexibility in the administration time relative to a meal. Which insulin type would be best for this patient?

    <p>Humalog (B), Apidra (D)</p> Signup and view all the answers

    A patient requires an insulin with a relatively short duration of action, ideally suitable for managing blood sugar levels during a single meal. Which insulin type would be the most appropriate choice in this scenario?

    <p>Fiasp (C)</p> Signup and view all the answers

    A patient prefers an insulin that can be administered shortly before a meal, but they may not always be able to inject exactly 15 minutes beforehand. Which insulin type offers the most flexibility in this aspect?

    <p>NovoLog (B), Apidra (C)</p> Signup and view all the answers

    Which insulin type, based on its administration guidelines, would present the least flexibility for a patient who frequently needs to adjust their mealtimes?

    <p>NovoLog (D)</p> Signup and view all the answers

    A patient's blood sugar levels consistently spike after a meal, even when they administer insulin as prescribed. Which insulin type, based on its onset time, would be most likely to offer a more rapid response and potentially address the issue of postprandial hyperglycemia?

    <p>Lyumjev (A)</p> Signup and view all the answers

    A patient is considering switching to a rapid-acting insulin that can be administered within a timeframe that is relatively more flexible than traditional insulin types. Based on the provided information, which insulin type(s) would be suitable for this purpose?

    <p>Humalog (A), Apidra (B), Fiasp (C)</p> Signup and view all the answers

    Which insulin type, when concentrated, significantly extends its duration of action, exceeding the typical range for regular insulin?

    <p>Humulin R U-500 (C)</p> Signup and view all the answers

    Which insulin type is characterized by a rapid onset and a relatively brief duration of action, making it particularly suited for managing post-meal blood sugar spikes?

    <p>Afrezza (inhalation) (A)</p> Signup and view all the answers

    Which insulin type is typically administered twice daily to ensure consistent basal insulin coverage throughout the day?

    <p>Humulin N (B)</p> Signup and view all the answers

    Which insulin type requires a significant time window between administration and the beginning of a meal, aiming to achieve optimal glucose control?

    <p>Humulin R U-100 (B)</p> Signup and view all the answers

    Which insulin type is uniquely administered via inhalation, offering a convenient and rapid-acting option for managing blood sugar levels?

    <p>Afrezza (inhalation) (C)</p> Signup and view all the answers

    Which insulin type exhibits a prolonged onset time, taking 1.5 hours to reach its full effect, making it less suitable for immediate pre-meal adjustments?

    <p>Humulin N (D)</p> Signup and view all the answers

    Which insulin type, despite being classified as regular insulin, displays a significantly extended duration of action due to its concentrated formulation?

    <p>Humulin R U-500 (D)</p> Signup and view all the answers

    Which insulin type is typically recommended for patients requiring a prolonged basal insulin coverage, lasting for up to 24 hours, often necessitating twice daily administration?

    <p>Humulin N (D)</p> Signup and view all the answers

    Which insulin type is best suited for achieving a quick reduction in blood glucose levels, especially after a meal, due to its rapid onset and shorter duration of action?

    <p>Afrezza (inhalation) (A)</p> Signup and view all the answers

    Which insulin type, although a regular insulin, exhibits a substantially prolonged duration of action due to its concentrated formulation, surpassing the typical duration of standard regular insulin?

    <p>Humulin R U-500 (B)</p> Signup and view all the answers

    Which insulin type, with once daily administration, may necessitate a dosage adjustment based on the time of administration relative to a meal?

    <p>Humulin U-500 (B)</p> Signup and view all the answers

    Which of the following statements accurately reflects the recommended administration time for Humulin U-500?

    <p>Administer 30 minutes prior to a meal, but assess the need for administration with every meal. (B)</p> Signup and view all the answers

    In the context of insulin therapy, achieving '24 hours basal insulin coverage' refers to:

    <p>Maintaining a steady, consistent level of insulin in the bloodstream throughout the day. (D)</p> Signup and view all the answers

    Which of the following insulins has the longest duration of action in the context of the provided information?

    <p>Lantus (C), Basaglar (D)</p> Signup and view all the answers

    Which insulin type would be most appropriate for a patient who needs a quick-acting insulin for managing post-meal blood sugar spikes?

    <p>Novolin N (B)</p> Signup and view all the answers

    The recommendation to check glucose levels prior to administering insulin is primarily intended to prevent:

    <p>Insulin stacking, which can lead to hypoglycemia. (D)</p> Signup and view all the answers

    Which insulin type is most likely to be prescribed for a patient who requires a longer-lasting insulin to manage blood sugar overnight?

    <p>Basaglar (A), Lantus (B)</p> Signup and view all the answers

    The statement 'Twice daily dosing aligns better with glucose coverage needs' in the context of Humulin U-500 suggests that:

    <p>Humulin U-500's duration of action is best matched to twice daily administration. (D)</p> Signup and view all the answers

    If a patient requires a rapid-acting insulin to quickly manage a post-meal blood sugar spike, which option would be the most suitable?

    <p>Novolin N (D)</p> Signup and view all the answers

    A patient has been prescribed a medication that helps manage post-meal blood sugar spikes by increasing insulin secretion. Which of the following medication classes is MOST LIKELY to be prescribed?

    <p>Sulfonylureas (B)</p> Signup and view all the answers

    Which drug from the provided list would be MOST indicated for a patient needing to enhance insulin sensitivity, leading to improved glucose uptake by tissues?

    <p>Pioglitazone (B)</p> Signup and view all the answers

    A patient is experiencing frequent episodes of hyperglycemia despite taking a sulfonylurea medication. Which medication class, when added to the patient's regimen, could effectively address this situation by acting on a different mechanism to improve glucose control?

    <p>Biguanides (A)</p> Signup and view all the answers

    Which of the following drugs is NOT a member of the SGLT-2 inhibitor class?

    <p>Saxagliptin (A)</p> Signup and view all the answers

    A patient needs to adjust their medication regimen after experiencing persistent hyperglycemia. They are currently taking a DPP-4 inhibitor. Which of the following medication classes, when added to the regimen, can help control blood sugar levels through a different mechanism?

    <p>Thiazolidinediones (TZDs) (B), SGLT-2 Inhibitors (C), GLP-1 Receptor Agonists (D)</p> Signup and view all the answers

    Which drug classification for diabetes treatment includes the following: Glimepiride, Glyburide, and Glipizide?

    <p>Sulfonylureas (A)</p> Signup and view all the answers

    Which drug classification, typically prescribed for type 2 diabetes, works by increasing insulin sensitivity and decreasing glucose production by the liver?

    <p>Thiazolidinediones (TZDs) (A)</p> Signup and view all the answers

    Which drug classification works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine?

    <p>SGLT-2 Inhibitors (B)</p> Signup and view all the answers

    Which of the following generic names is NOT associated with the DPP-4 inhibitor class of medications?

    <p>Canagliflozin (A)</p> Signup and view all the answers

    A patient reports experiencing frequent episodes of post-meal hyperglycemia. Which drug classification, known for its quick onset and shorter duration of action, would be most appropriate for addressing this specific issue?

    <p>GLP-1 Receptor Agonists (B)</p> Signup and view all the answers

    Which drug class utilizes a mechanism of action that involves increasing insulin sensitivity in peripheral tissues?

    <p>Thiazolidinediones (TZDs) (B)</p> Signup and view all the answers

    Which of these drug classes directly stimulates the release of insulin from pancreatic beta cells?

    <p>Sulfonylureas (C)</p> Signup and view all the answers

    Which of these drug classes acts by inhibiting the breakdown of incretin hormones, thereby increasing their levels and enhancing insulin secretion?

    <p>DPP-4 Inhibitors (B)</p> Signup and view all the answers

    Which drug class works by blocking the reabsorption of glucose in the kidneys, leading to an increase in urinary glucose excretion?

    <p>SGLT-2 Inhibitors (A)</p> Signup and view all the answers

    Which of these drug classes is NOT directly involved in regulating insulin secretion or sensitivity?

    <p>Biguanides (A)</p> Signup and view all the answers

    Flashcards

    Fiasp

    Ultra-rapid acting insulin that starts working in about 5-10 minutes.

    Lyumjev

    An ultra-rapid insulin similar to lispro, acting in ~15 minutes.

    Admelog

    Rapid acting insulin; take 15 minutes before or after meals.

    Humalog

    A rapid acting insulin that works within 15-30 minutes.

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    NovoLog

    Rapid acting insulin acting in 10-20 minutes before meals.

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    Apidra

    Rapid acting insulin effective 20 minutes around meals.

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    Onset

    The time it takes for insulin to start working.

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    Duration

    The length of time insulin remains effective in lowering blood sugar.

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    Administration

    The method of delivering insulin (usually subcutaneously).

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    Subcutaneous

    Means administering insulin under the skin.

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    Short Acting Insulin

    Insulin that begins to work quickly, typically within 30 minutes.

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    Humalin R U-100

    Regular insulin, short acting, needs injection 30 minutes before meals.

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    Novolin R U-100

    Another brand of regular insulin, with similar properties to Humalin R.

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    Afrezza

    Inhalation insulin that works quickly, with onset in 12-20 minutes.

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    Duration of Action (Regular Insulin)

    Regular insulin typically lasts about 8 hours after injection.

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    Humulin R U-500

    Concentrated regular insulin, with longer duration of action (up to 21 hours).

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    Intermediate Acting Insulin

    Insulin that covers basal needs for 12-24 hours; injected 1-2 times daily.

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    Humulin N

    Intermediate acting insulin that begins working in 1.5 hours and lasts 12-24 hours.

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    Onset of Insulin

    The time it takes for insulin to start lowering blood sugar levels after injection.

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    Administration Before Meals

    Short acting insulins should be injected 30 minutes before meals for optimal effect.

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    Novolin N

    A type of insulin with an onset of 1.5 hours and duration of 12-24 hours.

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    Humalin U-500

    Insulin with a ~30 minutes onset and duration range of 13-24 hours.

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    Long Acting Insulin

    Insulin designed for once daily injection to provide extended blood sugar control.

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    Lantus

    A long-acting insulin that usually requires once-daily administration.

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    Basaglar

    Another long-acting insulin like Lantus, used once daily.

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    Dosing Frequency

    Refers to how often insulin should be injected, typically once or twice daily.

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    Insulin Stacking

    When insulin is injected before previous doses have worn off, risking low blood sugar.

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    Injection Timing

    The recommended time to inject insulin before meals, often around 30 minutes.

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    Basal Insulin

    Insulin that maintains blood sugar levels during fasting periods.

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    Glucose Coverage

    The ability of insulin to manage glucose levels in the body.

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    Fiasp Administration

    Inject Fiasp at meal start or within 20 minutes after.

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    Lyumjev Onset

    Lyumjev starts working in approximately 15 minutes.

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    Admelog Injection Timing

    Inject Admelog 15 minutes before or immediately after meals.

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    Humalog Use

    Humalog should be injected 15 minutes before meals or right after.

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    NovoLog Administration

    NovoLog is injected 5-10 minutes before a meal.

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    Apidra Timing

    Apidra is injected 20 minutes before or within 20 minutes after meals.

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    Ultra-Rapid Insulin

    Types include Fiasp and Lyumjev, acting within 5-15 minutes.

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    Rapid Acting Insulin

    Includes Admelog, Humalog, NovoLog, Apidra, lasting around 3-5 hours.

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    Insulin Onset Variation

    Ultra-rapid insulins have onset times of 5-20 minutes.

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    Subcutaneous Injection

    Common method for administering many insulins, including ultra-rapid.

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    Twice Daily Insulin Dosing

    Recommended for certain insulins like Novolin N to achieve adequate glucose coverage throughout the day.

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    Basal Insulin Coverage

    Insulin needed to maintain blood sugar levels during fasting times, crucial for diabetes management.

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    Glucose Coverage Needs

    Refers to insulin's ability to manage blood glucose levels effectively throughout the day.

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    Afrezza Administration

    Inhalation insulin that should be inhaled at the beginning of a meal for effective use.

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    Duration of Humulin N

    The duration of Humulin N is 12-24 hours, providing basal insulin coverage.

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    Short Acting Insulin Timing

    Short acting insulin should be injected 30 minutes before meals for optimal effect.

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    Humulin N Onset

    Humulin N begins working in about 1.5 hours after injection.

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    Insulin Concentration Effect

    Higher concentrations of insulin can lead to a prolonged duration of action.

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    Afrezza Onset

    Afrezza has an onset of 12-20 minutes, making it faster than regular insulin.

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    Regular Insulin Duration

    Regular insulin typically lasts about 8 hours after injection.

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    Humulin N Administration Frequency

    Humulin N is usually injected once to twice daily for effective coverage.

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    Biguanides

    A class of medications that improve insulin sensitivity and lower hepatic glucose output; Metformin is the primary agent.

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    Sulfonylureas

    Medications that stimulate the pancreas to release more insulin; common examples include Glimepiride, Glyburide, and Glipizide.

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    DPP-4 Inhibitors

    Medications that increase incretin levels, leading to increased insulin secretion and decreased glucagon; examples include Sitagliptin and Saxagliptin.

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    SGLT-2 Inhibitors

    A class of drugs that prevent glucose reabsorption in the kidneys, leading to increased glucose excretion; Canagliflozin and Dapagliflozin are examples.

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    GLP-1 Receptor Agonists

    Drugs that mimic GLP-1, enhancing glucose-dependent insulin secretion; Semaglutide and Dulaglutide are notable examples.

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    Study Notes

    Insulin Types and Actions

    • Ultra-rapid acting insulins: Faster onset and shorter duration of action.
      • Fiasp (insulin aspart): Onset ~5-10 minutes, duration 3-5 hours. Formulated with niacinamide for faster absorption. Administered at mealtime or within 20 minutes of meal
      • Lyumjev (insulin lispro-aabc): Onset ~15 minutes, duration 3-5 hours. Administered at mealtime or within 20 minutes of meal
    • Rapid acting insulins: Faster onset and shorter duration than intermediate insulins.
      • Admelog (insulin lispro): Onset 15-30 minutes, duration 3-5 hours. Administered 15 minutes before meals, or immediately after.
      • Humalog (insulin lispro): Onset 15-30 minutes, duration 3-5 hours. Administered 15 minutes before meals, or immediately after.
      • NovoLog (insulin aspart): Onset 10-20 minutes, duration 3-5 hours. Administered 5-10 minutes before meals.
      • Apidra (insulin glulisine): Onset 20 minutes, duration 3-5 hours. Administered within 15 minutes before meals, or within 20 minutes after starting a meal.

    Short-acting insulins (Regular insulin):

    • Humulin R U-100 (regular insulin): Onset 30 minutes, duration 8 hours. Administered 30 minutes prior to meals.
    • Novolin R U-100 (regular insulin): Onset 30 minutes, duration 8 hours. Administered 30 minutes prior to meals.
    • Afrezza (inhalation): Onset 12-20 minutes, duration 2.5-3 hours. Inhaled at mealtime
    • Humulin R U-500 (concentrated regular insulin): Onset 30 minutes; duration ~21 hours. Higher concentration leads to longer duration.

    Intermediate-acting insulins:

    • Humulin N: Onset 1.5 hours, Duration 12-24 hours. Administered once or twice daily; Twice daily dosing is more common.
    • Novolin N: Onset 1.5 hours, Duration 12-24 hours. Administered once or twice daily; Twice daily dosing is more common.

    Long-acting insulins:

    • Lantus (insulin glargine): Onset 1.5 hours, Duration ~24 hours. Administered once daily, or twice daily in some cases.
    • Basaglar (insulin glargine): Onset 1.5 hours, Duration ~24 hours. Administered once daily, or twice daily in some cases.
    • Semglee (insulin glargine-yfgn): Onset 1.5 hours, Duration ~24 hours. Administered once daily.
    • Rezvoglar (Insulin glargine-aglr): Onset 1.5 hours, Duration ~24 hours. Administered once daily.
    • Toujeo (insulin glargine): Onset ~1 hour, Duration 24-36 hours. Administered once daily.

    Ultra-long-acting insulin:

    • Tresiba (insulin degludec): Onset 1.5 hours, Duration 36-42 hours. Administered once daily.

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    Test your knowledge on the various types of insulin, their onset times, durations of action, and recommended administration practices. This quiz will help you understand the differences between Humulin R, Humulin N, and Afrezza insulin. Perfect for students and healthcare professionals alike.

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