Podcast
Questions and Answers
What is the onset time of Humulin R U-100 regular insulin?
What is the onset time of Humulin R U-100 regular insulin?
How long does the duration of action last for Afrezza (inhalation) regular insulin?
How long does the duration of action last for Afrezza (inhalation) regular insulin?
What is the difference in the duration of action between Humulin R U-100 regular insulin and Humulin R U-500 concentrated regular insulin?
What is the difference in the duration of action between Humulin R U-100 regular insulin and Humulin R U-500 concentrated regular insulin?
How often is Humulin N intermediate acting insulin administered?
How often is Humulin N intermediate acting insulin administered?
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Which type of insulin is recommended for injecting 30 minutes prior to a meal?
Which type of insulin is recommended for injecting 30 minutes prior to a meal?
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What is the onset time for Humulin N intermediate acting insulin?
What is the onset time for Humulin N intermediate acting insulin?
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Based on the information provided, what is the primary difference between Humulin R U-100 and Humulin R U-500?
Based on the information provided, what is the primary difference between Humulin R U-100 and Humulin R U-500?
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What is the recommended time to administer Afrezza (inhalation) insulin?
What is the recommended time to administer Afrezza (inhalation) insulin?
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Which insulin type is most suitable for achieving 24 hours of basal insulin coverage?
Which insulin type is most suitable for achieving 24 hours of basal insulin coverage?
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Which of these insulin types is most likely to be prescribed for a patient who requires a quick-acting insulin for managing post-meal blood sugar spikes?
Which of these insulin types is most likely to be prescribed for a patient who requires a quick-acting insulin for managing post-meal blood sugar spikes?
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Which insulin type requires twice daily injections to achieve a 24 hours basal insulin coverage?
Which insulin type requires twice daily injections to achieve a 24 hours basal insulin coverage?
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Which insulin type has a mean duration of ~21 hours?
Which insulin type has a mean duration of ~21 hours?
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Which insulin types are generally administered once daily but can be adjusted to twice daily for some patients?
Which insulin types are generally administered once daily but can be adjusted to twice daily for some patients?
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In general, for most patients, administering Novolin N twice daily is necessary to achieve what?
In general, for most patients, administering Novolin N twice daily is necessary to achieve what?
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Administering Humulin U-500 twice daily is recommended to align with what?
Administering Humulin U-500 twice daily is recommended to align with what?
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How long does the duration of the insulin action last for Novolin N?
How long does the duration of the insulin action last for Novolin N?
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What is the recommended administration time for Novolin N?
What is the recommended administration time for Novolin N?
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What is the primary reason for checking glucose levels before administering insulin?
What is the primary reason for checking glucose levels before administering insulin?
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What is the relationship between twice daily administration and the effects of Lantus or Basaglar?
What is the relationship between twice daily administration and the effects of Lantus or Basaglar?
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Which of the following statements about Novolin N is correct?
Which of the following statements about Novolin N is correct?
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Which insulin type would be most appropriate for a patient who needs to take their insulin right before or after a meal, but needs the insulin to work quickly?
Which insulin type would be most appropriate for a patient who needs to take their insulin right before or after a meal, but needs the insulin to work quickly?
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Which insulin(s) should be administered subcutaneously into the abdomen, upper arm, thigh, or buttocks?
Which insulin(s) should be administered subcutaneously into the abdomen, upper arm, thigh, or buttocks?
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Which insulin has the shortest onset time of action?
Which insulin has the shortest onset time of action?
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Which insulin has the longest duration of action?
Which insulin has the longest duration of action?
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A patient is experiencing a sudden spike in blood sugar levels after a meal. Which insulin is the best option for this situation?
A patient is experiencing a sudden spike in blood sugar levels after a meal. Which insulin is the best option for this situation?
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Which insulin requires a dosage adjustment based on the time of administration relative to a meal?
Which insulin requires a dosage adjustment based on the time of administration relative to a meal?
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What unique characteristic of Fiasp allows for faster absorption?
What unique characteristic of Fiasp allows for faster absorption?
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Which insulin can be taken up to 20 minutes after the start of a meal?
Which insulin can be taken up to 20 minutes after the start of a meal?
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A patient needs an insulin with a longer duration of action for overnight management. Which insulin would be the BEST choice for this patient?
A patient needs an insulin with a longer duration of action for overnight management. Which insulin would be the BEST choice for this patient?
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Considering a patient's need for mealtime insulin, which of the following is TRUE about Lyumjev?
Considering a patient's need for mealtime insulin, which of the following is TRUE about Lyumjev?
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Which insulin type, based on its administration guidelines, would be the most suitable option for a patient who frequently forgets to take their insulin before meals?
Which insulin type, based on its administration guidelines, would be the most suitable option for a patient who frequently forgets to take their insulin before meals?
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A patient needs a rapid-acting insulin that can be administered 15 minutes before a meal but also provides flexibility to be taken immediately after eating. Which insulin type would be the most suitable choice in this scenario?
A patient needs a rapid-acting insulin that can be administered 15 minutes before a meal but also provides flexibility to be taken immediately after eating. Which insulin type would be the most suitable choice in this scenario?
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A patient is experiencing a sudden, unexpected spike in blood sugar levels following a meal. Which insulin type, based on its onset time, would be the most appropriate to address this situation quickly?
A patient is experiencing a sudden, unexpected spike in blood sugar levels following a meal. Which insulin type, based on its onset time, would be the most appropriate to address this situation quickly?
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From the provided list, which insulin type(s) would be considered the most appropriate for a patient aiming to achieve a rapid reduction in blood sugar levels following a meal, thus minimizing the risk of postprandial hyperglycemia?
From the provided list, which insulin type(s) would be considered the most appropriate for a patient aiming to achieve a rapid reduction in blood sugar levels following a meal, thus minimizing the risk of postprandial hyperglycemia?
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A patient needs to carefully manage their postprandial blood sugar levels and prefers a rapid-acting insulin that offers some flexibility in the administration time relative to a meal. Which insulin type would be best for this patient?
A patient needs to carefully manage their postprandial blood sugar levels and prefers a rapid-acting insulin that offers some flexibility in the administration time relative to a meal. Which insulin type would be best for this patient?
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A patient requires an insulin with a relatively short duration of action, ideally suitable for managing blood sugar levels during a single meal. Which insulin type would be the most appropriate choice in this scenario?
A patient requires an insulin with a relatively short duration of action, ideally suitable for managing blood sugar levels during a single meal. Which insulin type would be the most appropriate choice in this scenario?
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A patient prefers an insulin that can be administered shortly before a meal, but they may not always be able to inject exactly 15 minutes beforehand. Which insulin type offers the most flexibility in this aspect?
A patient prefers an insulin that can be administered shortly before a meal, but they may not always be able to inject exactly 15 minutes beforehand. Which insulin type offers the most flexibility in this aspect?
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Which insulin type, based on its administration guidelines, would present the least flexibility for a patient who frequently needs to adjust their mealtimes?
Which insulin type, based on its administration guidelines, would present the least flexibility for a patient who frequently needs to adjust their mealtimes?
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A patient's blood sugar levels consistently spike after a meal, even when they administer insulin as prescribed. Which insulin type, based on its onset time, would be most likely to offer a more rapid response and potentially address the issue of postprandial hyperglycemia?
A patient's blood sugar levels consistently spike after a meal, even when they administer insulin as prescribed. Which insulin type, based on its onset time, would be most likely to offer a more rapid response and potentially address the issue of postprandial hyperglycemia?
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A patient is considering switching to a rapid-acting insulin that can be administered within a timeframe that is relatively more flexible than traditional insulin types. Based on the provided information, which insulin type(s) would be suitable for this purpose?
A patient is considering switching to a rapid-acting insulin that can be administered within a timeframe that is relatively more flexible than traditional insulin types. Based on the provided information, which insulin type(s) would be suitable for this purpose?
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Which insulin type, when concentrated, significantly extends its duration of action, exceeding the typical range for regular insulin?
Which insulin type, when concentrated, significantly extends its duration of action, exceeding the typical range for regular insulin?
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Which insulin type is characterized by a rapid onset and a relatively brief duration of action, making it particularly suited for managing post-meal blood sugar spikes?
Which insulin type is characterized by a rapid onset and a relatively brief duration of action, making it particularly suited for managing post-meal blood sugar spikes?
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Which insulin type is typically administered twice daily to ensure consistent basal insulin coverage throughout the day?
Which insulin type is typically administered twice daily to ensure consistent basal insulin coverage throughout the day?
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Which insulin type requires a significant time window between administration and the beginning of a meal, aiming to achieve optimal glucose control?
Which insulin type requires a significant time window between administration and the beginning of a meal, aiming to achieve optimal glucose control?
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Which insulin type is uniquely administered via inhalation, offering a convenient and rapid-acting option for managing blood sugar levels?
Which insulin type is uniquely administered via inhalation, offering a convenient and rapid-acting option for managing blood sugar levels?
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Which insulin type exhibits a prolonged onset time, taking 1.5 hours to reach its full effect, making it less suitable for immediate pre-meal adjustments?
Which insulin type exhibits a prolonged onset time, taking 1.5 hours to reach its full effect, making it less suitable for immediate pre-meal adjustments?
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Which insulin type, despite being classified as regular insulin, displays a significantly extended duration of action due to its concentrated formulation?
Which insulin type, despite being classified as regular insulin, displays a significantly extended duration of action due to its concentrated formulation?
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Which insulin type is typically recommended for patients requiring a prolonged basal insulin coverage, lasting for up to 24 hours, often necessitating twice daily administration?
Which insulin type is typically recommended for patients requiring a prolonged basal insulin coverage, lasting for up to 24 hours, often necessitating twice daily administration?
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Which insulin type is best suited for achieving a quick reduction in blood glucose levels, especially after a meal, due to its rapid onset and shorter duration of action?
Which insulin type is best suited for achieving a quick reduction in blood glucose levels, especially after a meal, due to its rapid onset and shorter duration of action?
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Which insulin type, although a regular insulin, exhibits a substantially prolonged duration of action due to its concentrated formulation, surpassing the typical duration of standard regular insulin?
Which insulin type, although a regular insulin, exhibits a substantially prolonged duration of action due to its concentrated formulation, surpassing the typical duration of standard regular insulin?
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Which insulin type, with once daily administration, may necessitate a dosage adjustment based on the time of administration relative to a meal?
Which insulin type, with once daily administration, may necessitate a dosage adjustment based on the time of administration relative to a meal?
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Which of the following statements accurately reflects the recommended administration time for Humulin U-500?
Which of the following statements accurately reflects the recommended administration time for Humulin U-500?
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In the context of insulin therapy, achieving '24 hours basal insulin coverage' refers to:
In the context of insulin therapy, achieving '24 hours basal insulin coverage' refers to:
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Which of the following insulins has the longest duration of action in the context of the provided information?
Which of the following insulins has the longest duration of action in the context of the provided information?
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Which insulin type would be most appropriate for a patient who needs a quick-acting insulin for managing post-meal blood sugar spikes?
Which insulin type would be most appropriate for a patient who needs a quick-acting insulin for managing post-meal blood sugar spikes?
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The recommendation to check glucose levels prior to administering insulin is primarily intended to prevent:
The recommendation to check glucose levels prior to administering insulin is primarily intended to prevent:
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Which insulin type is most likely to be prescribed for a patient who requires a longer-lasting insulin to manage blood sugar overnight?
Which insulin type is most likely to be prescribed for a patient who requires a longer-lasting insulin to manage blood sugar overnight?
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The statement 'Twice daily dosing aligns better with glucose coverage needs' in the context of Humulin U-500 suggests that:
The statement 'Twice daily dosing aligns better with glucose coverage needs' in the context of Humulin U-500 suggests that:
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If a patient requires a rapid-acting insulin to quickly manage a post-meal blood sugar spike, which option would be the most suitable?
If a patient requires a rapid-acting insulin to quickly manage a post-meal blood sugar spike, which option would be the most suitable?
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A patient has been prescribed a medication that helps manage post-meal blood sugar spikes by increasing insulin secretion. Which of the following medication classes is MOST LIKELY to be prescribed?
A patient has been prescribed a medication that helps manage post-meal blood sugar spikes by increasing insulin secretion. Which of the following medication classes is MOST LIKELY to be prescribed?
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Which drug from the provided list would be MOST indicated for a patient needing to enhance insulin sensitivity, leading to improved glucose uptake by tissues?
Which drug from the provided list would be MOST indicated for a patient needing to enhance insulin sensitivity, leading to improved glucose uptake by tissues?
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A patient is experiencing frequent episodes of hyperglycemia despite taking a sulfonylurea medication. Which medication class, when added to the patient's regimen, could effectively address this situation by acting on a different mechanism to improve glucose control?
A patient is experiencing frequent episodes of hyperglycemia despite taking a sulfonylurea medication. Which medication class, when added to the patient's regimen, could effectively address this situation by acting on a different mechanism to improve glucose control?
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Which of the following drugs is NOT a member of the SGLT-2 inhibitor class?
Which of the following drugs is NOT a member of the SGLT-2 inhibitor class?
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A patient needs to adjust their medication regimen after experiencing persistent hyperglycemia. They are currently taking a DPP-4 inhibitor. Which of the following medication classes, when added to the regimen, can help control blood sugar levels through a different mechanism?
A patient needs to adjust their medication regimen after experiencing persistent hyperglycemia. They are currently taking a DPP-4 inhibitor. Which of the following medication classes, when added to the regimen, can help control blood sugar levels through a different mechanism?
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Which drug classification for diabetes treatment includes the following: Glimepiride
, Glyburide
, and Glipizide
?
Which drug classification for diabetes treatment includes the following: Glimepiride
, Glyburide
, and Glipizide
?
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Which drug classification, typically prescribed for type 2 diabetes, works by increasing insulin sensitivity and decreasing glucose production by the liver?
Which drug classification, typically prescribed for type 2 diabetes, works by increasing insulin sensitivity and decreasing glucose production by the liver?
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Which drug classification works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine?
Which drug classification works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine?
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Which of the following generic names is NOT associated with the DPP-4 inhibitor class of medications?
Which of the following generic names is NOT associated with the DPP-4 inhibitor class of medications?
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A patient reports experiencing frequent episodes of post-meal hyperglycemia. Which drug classification, known for its quick onset and shorter duration of action, would be most appropriate for addressing this specific issue?
A patient reports experiencing frequent episodes of post-meal hyperglycemia. Which drug classification, known for its quick onset and shorter duration of action, would be most appropriate for addressing this specific issue?
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Which drug class utilizes a mechanism of action that involves increasing insulin sensitivity in peripheral tissues?
Which drug class utilizes a mechanism of action that involves increasing insulin sensitivity in peripheral tissues?
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Which of these drug classes directly stimulates the release of insulin from pancreatic beta cells?
Which of these drug classes directly stimulates the release of insulin from pancreatic beta cells?
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Which of these drug classes acts by inhibiting the breakdown of incretin hormones, thereby increasing their levels and enhancing insulin secretion?
Which of these drug classes acts by inhibiting the breakdown of incretin hormones, thereby increasing their levels and enhancing insulin secretion?
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Which drug class works by blocking the reabsorption of glucose in the kidneys, leading to an increase in urinary glucose excretion?
Which drug class works by blocking the reabsorption of glucose in the kidneys, leading to an increase in urinary glucose excretion?
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Which of these drug classes is NOT directly involved in regulating insulin secretion or sensitivity?
Which of these drug classes is NOT directly involved in regulating insulin secretion or sensitivity?
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Flashcards
Fiasp
Fiasp
Ultra-rapid acting insulin that starts working in about 5-10 minutes.
Lyumjev
Lyumjev
An ultra-rapid insulin similar to lispro, acting in ~15 minutes.
Admelog
Admelog
Rapid acting insulin; take 15 minutes before or after meals.
Humalog
Humalog
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NovoLog
NovoLog
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Apidra
Apidra
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Onset
Onset
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Duration
Duration
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Administration
Administration
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Subcutaneous
Subcutaneous
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Short Acting Insulin
Short Acting Insulin
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Humalin R U-100
Humalin R U-100
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Novolin R U-100
Novolin R U-100
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Afrezza
Afrezza
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Duration of Action (Regular Insulin)
Duration of Action (Regular Insulin)
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Humulin R U-500
Humulin R U-500
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Intermediate Acting Insulin
Intermediate Acting Insulin
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Humulin N
Humulin N
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Onset of Insulin
Onset of Insulin
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Administration Before Meals
Administration Before Meals
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Novolin N
Novolin N
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Humalin U-500
Humalin U-500
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Long Acting Insulin
Long Acting Insulin
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Lantus
Lantus
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Basaglar
Basaglar
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Dosing Frequency
Dosing Frequency
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Insulin Stacking
Insulin Stacking
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Injection Timing
Injection Timing
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Basal Insulin
Basal Insulin
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Glucose Coverage
Glucose Coverage
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Fiasp Administration
Fiasp Administration
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Lyumjev Onset
Lyumjev Onset
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Admelog Injection Timing
Admelog Injection Timing
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Humalog Use
Humalog Use
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NovoLog Administration
NovoLog Administration
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Apidra Timing
Apidra Timing
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Ultra-Rapid Insulin
Ultra-Rapid Insulin
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Rapid Acting Insulin
Rapid Acting Insulin
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Insulin Onset Variation
Insulin Onset Variation
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Subcutaneous Injection
Subcutaneous Injection
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Twice Daily Insulin Dosing
Twice Daily Insulin Dosing
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Basal Insulin Coverage
Basal Insulin Coverage
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Glucose Coverage Needs
Glucose Coverage Needs
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Afrezza Administration
Afrezza Administration
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Duration of Humulin N
Duration of Humulin N
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Short Acting Insulin Timing
Short Acting Insulin Timing
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Humulin N Onset
Humulin N Onset
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Insulin Concentration Effect
Insulin Concentration Effect
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Afrezza Onset
Afrezza Onset
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Regular Insulin Duration
Regular Insulin Duration
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Humulin N Administration Frequency
Humulin N Administration Frequency
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Biguanides
Biguanides
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Sulfonylureas
Sulfonylureas
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DPP-4 Inhibitors
DPP-4 Inhibitors
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SGLT-2 Inhibitors
SGLT-2 Inhibitors
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GLP-1 Receptor Agonists
GLP-1 Receptor Agonists
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Study Notes
Insulin Types and Actions
- Ultra-rapid acting insulins: Faster onset and shorter duration of action.
- Fiasp (insulin aspart): Onset ~5-10 minutes, duration 3-5 hours. Formulated with niacinamide for faster absorption. Administered at mealtime or within 20 minutes of meal
- Lyumjev (insulin lispro-aabc): Onset ~15 minutes, duration 3-5 hours. Administered at mealtime or within 20 minutes of meal
- Rapid acting insulins: Faster onset and shorter duration than intermediate insulins.
- Admelog (insulin lispro): Onset 15-30 minutes, duration 3-5 hours. Administered 15 minutes before meals, or immediately after.
- Humalog (insulin lispro): Onset 15-30 minutes, duration 3-5 hours. Administered 15 minutes before meals, or immediately after.
- NovoLog (insulin aspart): Onset 10-20 minutes, duration 3-5 hours. Administered 5-10 minutes before meals.
- Apidra (insulin glulisine): Onset 20 minutes, duration 3-5 hours. Administered within 15 minutes before meals, or within 20 minutes after starting a meal.
Short-acting insulins (Regular insulin):
- Humulin R U-100 (regular insulin): Onset 30 minutes, duration 8 hours. Administered 30 minutes prior to meals.
- Novolin R U-100 (regular insulin): Onset 30 minutes, duration 8 hours. Administered 30 minutes prior to meals.
- Afrezza (inhalation): Onset 12-20 minutes, duration 2.5-3 hours. Inhaled at mealtime
- Humulin R U-500 (concentrated regular insulin): Onset 30 minutes; duration ~21 hours. Higher concentration leads to longer duration.
Intermediate-acting insulins:
- Humulin N: Onset 1.5 hours, Duration 12-24 hours. Administered once or twice daily; Twice daily dosing is more common.
- Novolin N: Onset 1.5 hours, Duration 12-24 hours. Administered once or twice daily; Twice daily dosing is more common.
Long-acting insulins:
- Lantus (insulin glargine): Onset 1.5 hours, Duration ~24 hours. Administered once daily, or twice daily in some cases.
- Basaglar (insulin glargine): Onset 1.5 hours, Duration ~24 hours. Administered once daily, or twice daily in some cases.
- Semglee (insulin glargine-yfgn): Onset 1.5 hours, Duration ~24 hours. Administered once daily.
- Rezvoglar (Insulin glargine-aglr): Onset 1.5 hours, Duration ~24 hours. Administered once daily.
- Toujeo (insulin glargine): Onset ~1 hour, Duration 24-36 hours. Administered once daily.
Ultra-long-acting insulin:
- Tresiba (insulin degludec): Onset 1.5 hours, Duration 36-42 hours. Administered once daily.
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Description
Test your knowledge on the various types of insulin, their onset times, durations of action, and recommended administration practices. This quiz will help you understand the differences between Humulin R, Humulin N, and Afrezza insulin. Perfect for students and healthcare professionals alike.