Instrumentation: Accuracy, Precision, and LOD Concepts
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Questions and Answers

What does accuracy refer to in the context of measurement?

  • The degree to which the result of a measurement conforms to the correct value or a standard (correct)
  • The quality of being exact
  • The closeness of multiple observations to one another
  • The lowest concentration of the analyte that can be reliably detected and quantified

    • Which term refers to the quality of being exact and how close two or more measurements are to each other?

  • Precision (correct)
  • Limits of detection (LOD)
  • Systematic errors
  • Random errors

    • What are systematic errors in experimental observations primarily attributed to?

  • The closeness of multiple observations to one another
  • Unknown and unpredictable changes in the experiment
  • Inaccuracy inherent in the system (correct)
  • Measuring instruments or environmental conditions

    • What do random errors in experimental measurements result from?

    <p>Unknown and unpredictable changes in the experiment</p> Signup and view all the answers

    What does precision refer to in the context of measurement?

    <p>The quality of being exact and how close two or more measurements are to each other</p> Signup and view all the answers

    What does limits of detection (LOD) refer to in the context of measurement?

    <p>The lowest concentration of the analyte that can be reliably detected and quantified</p> Signup and view all the answers

    What is the main cause of random errors in an experiment?

    <p>Electronic noise in the circuit of an electrical instrument</p> Signup and view all the answers

    Which type of error can be replicated by repeating the experiment again?

    <p>Systematic errors</p> Signup and view all the answers

    What is the purpose of a reference standard in calibration?

    <p>To test the identity, strength, quality, and purity of substances</p> Signup and view all the answers

    What are Certified Reference Materials (CRMs) used for?

    <p>All of the above</p> Signup and view all the answers

    When is calibration typically required?

    <p>All of the above</p> Signup and view all the answers

    What is the goal of calibration?

    <p>To quantify and control errors or uncertainties within measurement processes</p> Signup and view all the answers

    What are Systematic errors usually caused by?

    <p>Measuring instruments that are incorrectly calibrated</p> Signup and view all the answers

    What is a working standard used for?

    <p>A standard that is qualified against and used instead of the reference standard</p> Signup and view all the answers

    Which of the following is most suitable to test the identity, strength, quality, and purity of substances for Chemical, pharmaceutical, and medicinal products?

    <p>Reference standards</p> Signup and view all the answers

    What is the comparison of measurement values delivered by a device under test with those of a calibration standard known as?

    <p>Calibration traceability</p> Signup and view all the answers

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