Innate Immune System Overview

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Questions and Answers

What characterizes the adaptive immune system after the initial exposure to a pathogen?

  • It develops memory for a quicker response upon re-exposure. (correct)
  • It activates immediately upon exposure.
  • It becomes slower with each re-exposure.
  • It produces antibodies only after the first exposure.

Which type of cells are involved in humoral immunity?

  • Macrophages
  • Natural killer cells
  • B cells (correct)
  • T cells

What role does innate immunity play in relation to adaptive immunity?

  • It suppresses the adaptive immune response to prevent overreactions.
  • It exclusively targets intracellular pathogens.
  • It serves as the first line of defense and interacts with adaptive immunity. (correct)
  • It functions independently without activating adaptive immunity.

What happens when a pathogen is re-encountered by the immune system?

<p>The immune response is accelerated due to memory of the antigen. (A)</p> Signup and view all the answers

How do antigen presenting cells, such as macrophages, contribute to the adaptive immune response?

<p>They activate CD4 T helper cells which then enhance adaptive immunity. (B)</p> Signup and view all the answers

What best describes an antigen?

<p>A substance that induces an immune response (A)</p> Signup and view all the answers

Which characteristic is NOT associated with the innate immune system?

<p>Memory development (B)</p> Signup and view all the answers

What is the first line of defense in the innate immune system?

<p>Physical barriers (D)</p> Signup and view all the answers

How does the innate immune system respond to an antigen after the first encounter?

<p>By maintaining the same type of response (C)</p> Signup and view all the answers

What describes the adaptive immune system?

<p>It develops memory throughout life (D)</p> Signup and view all the answers

Which of the following statements about the innate immune system is correct?

<p>It is the first response upon encountering antigens (B)</p> Signup and view all the answers

What is the role of leukocytes in the immune system?

<p>They are involved in both innate and adaptive immune responses (B)</p> Signup and view all the answers

Which feature distinguishes the adaptive immune system from the innate immune system?

<p>Development of immunological memory (D)</p> Signup and view all the answers

Flashcards

Antigen

A substance that triggers an immune response in the body.

Innate Immune System

The body's first line of defense against pathogens. It is non-specific and does not develop memory.

Inflammatory Response

The second line of defense in the immune system. It is characterized by redness, swelling, heat, and pain.

Adaptive Immune System

The immune system's ability to recognize and remember specific pathogens.

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Phagocytes

A type of white blood cell that plays a crucial role in the innate immune system. These cells engulf and destroy pathogens.

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Mast Cells

A type of white blood cell that releases chemicals that trigger inflammation.

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Antibodies

Special proteins that recognize and bind to specific antigens, marking them for destruction by immune cells.

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Natural Killer (NK) Cells

Immune cells that recognize and destroy cells infected with viruses or cancer.

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Immune Memory

The ability of the immune system to recognize and mount a quicker and more robust response to a previously encountered pathogen.

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Innate Immunity

The first line of defense against pathogens, acting rapidly and nonspecifically.

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Humoral Immunity

A type of adaptive immunity that involves B cells producing antibodies to target specific antigens.

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Cell-mediated Immunity

A type of adaptive immunity that involves T cells directly attacking infected cells or stimulating other immune cells.

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Antigen Presentation

The interaction between the innate and adaptive immune systems where innate immune cells, like macrophages, present antigens to T cells, triggering the adaptive response.

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Study Notes

Innate Immune System Overview

  • Antigen Definition: A substance triggering an immune response; targets of antibodies and white blood cells. Can be foreign microbes, infected cells, or abnormal tissues. Self-antigens are normal healthy cells.
  • Immune System Types: Consists of innate and adaptive immunity.
  • Innate Immunity: A non-specific, immediate immune response present at birth. It does not learn or develop memory; the response to an antigen is consistent each time. Key characteristics: immediate, broad, and lacks memory.
  • Innate Response Timing: The first response during antigen encounters.
  • Innate System Components: Composed of physical barriers (first line) and the inflammatory response (second line).
  • Cells Involved: Leukocytes (white blood cells) play a role. Refer to a separate Hematology pre-module PowerPoint for detailed information on leukocytes and their specific roles in different immune systems.
  • Study Note: Review the Hematology pre-module PowerPoint on leukocytes for detailed information.

Adaptive Immune System Overview

  • Adaptive/Acquired Immunity: A highly specific immune system that develops memory. It is slower initially, but subsequent responses to same pathogen are quicker.
  • Memory Development: Re-exposure to an antigen triggers a much faster immune response.
  • Adaptive Immunity Sub-types: Divided into humoral (B cells) and cell-mediated (T cells) immunity.
  • Further Study: The detailed study of adaptive immunity will be in a subsequent PowerPoint.

Relationship Between Innate and Adaptive Immunity

  • Innate Initial Response: The innate system is activated first.
  • Innate-Adaptive Interaction: The innate system interacts with the adaptive system. Antigen-presenting cells (e.g., macrophages) interact with CD4 T helper cells, which activates the adaptive immune response.
  • Further Study: More details on the interaction and processes will be covered in this and subsequent PowerPoints.

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