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Injectable Medications for Erectile Dysfunction

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Injectable Medications for Erectile Dysfunction

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Questions and Answers

What is the mechanism of action of alprostadil?

Inhibiting phosphodiesterase

Increasing urethral flow

Widening blood vessels (correct)

Enhancing lower urinary tract symptoms

Why is papaverine no longer available in the US and Canada?

Increased efficacy in treating ED

To avoid priapism risk

Development of more effective PDE-5 inhibitors (correct)

Due to high costs

What is the primary drawback of using MUSE for administering alprostadil?

Inability to bypass LUTS (correct)

High cost

Risk of priapism

Limited availability in pharmacies

Why is caution advised when using MUSE in patients with risk factors for priapism?

Fibrosis potential after long-term use Signup and view all the answers

What percentage of patients using alprostadil successfully achieve intercourse according to studies?

65-75% Signup and view all the answers

What is the main limitation of MUSE for men with erectile dysfunction caused by diabetes or radical prostate surgery?

Limited efficacy Signup and view all the answers

What is the recommended maximum dosage of Papaverine in a 24-hour period?

60mg Signup and view all the answers

Which medication has a success rate of 55-75% and comes in dosage strengths of 10, 20, or 40 μg per dose?

Caverject Signup and view all the answers

What is the primary mechanism of action for Papaverine in treating erectile dysfunction?

Inhibition of cAMP and cGMP phosphodiesterase Signup and view all the answers

Which medication combination has been shown to produce satisfactory erections in 60-70% of patients with chronic erectile dysfunction?

Papaverine and Phentolamine Signup and view all the answers

What is a common side effect associated with Caverject usage?

Prolonged erection Signup and view all the answers

Why is Phentolamine used in combination with Papaverine for erectile dysfunction treatment?

To block receptors for erections Signup and view all the answers