Podcast
Questions and Answers
Which of the following is the definition of reproductive integrity in the context of cell survival curves?
Which of the following is the definition of reproductive integrity in the context of cell survival curves?
- The ability of cells to divide indefinitely and generate a large clone of cells (correct)
- The loss of the capacity for sustained proliferation in proliferating cells
- The loss of a specific function in differentiated cells
- The inability of cells to divide and inhibit further growth
What is the dominant mechanism of cell death in most cells?
What is the dominant mechanism of cell death in most cells?
- Mitotic death (correct)
- Reproductive death
- Loss of proliferative capacity
- Apoptosis
What is the mean lethal dose for the loss of proliferative capacity in proliferating cells?
What is the mean lethal dose for the loss of proliferative capacity in proliferating cells?
- Less than 2 Gy (correct)
- More than 100 Gy
- 2 Gy
- Approximately 100 Gy
Which proteins monitor the cell cycle's progress and ensure accuracy?
Which proteins monitor the cell cycle's progress and ensure accuracy?
What is the significance of the cell cycle?
What is the significance of the cell cycle?
Which technique is used to produce synchronously dividing cell cultures?
Which technique is used to produce synchronously dividing cell cultures?
Which phase of the cell cycle shows the greatest resistance to radiation?
Which phase of the cell cycle shows the greatest resistance to radiation?
Which phase of the cell cycle is characterized by DNA replication?
Which phase of the cell cycle is characterized by DNA replication?
What is the dose required to reduce the fraction of surviving cells to 37% in the effective dose-survival curve?
What is the dose required to reduce the fraction of surviving cells to 37% in the effective dose-survival curve?
What is the dose required to kill 90% of the population in the effective dose-survival curve?
What is the dose required to kill 90% of the population in the effective dose-survival curve?
If a tumor contains 10^8 clonogenic cells, what total dose is required to give a 90% chance of tumor cure?
If a tumor contains 10^8 clonogenic cells, what total dose is required to give a 90% chance of tumor cure?
Which phase of the cell cycle is most resistant to radiation?
Which phase of the cell cycle is most resistant to radiation?
What is the cycle time for resting mouse skin stem cells?
What is the cycle time for resting mouse skin stem cells?
Which phase of the cell cycle has the second peak of resistance to radiation?
Which phase of the cell cycle has the second peak of resistance to radiation?
Which repair mechanism is more faithful and occurs after replication in the S phase?
Which repair mechanism is more faithful and occurs after replication in the S phase?
Which of the following is NOT a mechanism of cell killing ?
Which of the following is NOT a mechanism of cell killing ?
Which of the following is a characteristic of apoptosis?
Which of the following is a characteristic of apoptosis?
What is the equation for the surviving fraction in the multitarget model?
What is the equation for the surviving fraction in the multitarget model?
What is the relationship between radiosensitivity and apoptosis in mammalian cells?
What is the relationship between radiosensitivity and apoptosis in mammalian cells?
What does the α/β ratio in the linear-quadratic model indicate?
What does the α/β ratio in the linear-quadratic model indicate?
What is the role of autophagy in irradiated cells?
What is the role of autophagy in irradiated cells?
What is the cycle time for resting mouse skin stem cells?
What is the cycle time for resting mouse skin stem cells?
Which phase of the cell cycle is most resistant to radiation?
Which phase of the cell cycle is most resistant to radiation?
Which type of radiation displays a straight-line curve in the survival curve, approximating exponential cell killing?
Which type of radiation displays a straight-line curve in the survival curve, approximating exponential cell killing?
Which repair mechanism is more faithful and occurs after replication in the S phase?
Which repair mechanism is more faithful and occurs after replication in the S phase?
What is the plating efficiency in the unirradiated control dish if 100 cells were seeded and there are 70 colonies after 7 days?
What is the plating efficiency in the unirradiated control dish if 100 cells were seeded and there are 70 colonies after 7 days?
What is the dose required to kill 90% of the population in the effective dose-survival curve?
What is the dose required to kill 90% of the population in the effective dose-survival curve?
What is the equation for the surviving fraction in the multitarget model?
What is the equation for the surviving fraction in the multitarget model?
What is the relationship between radiosensitivity and apoptosis in mammalian cells?
What is the relationship between radiosensitivity and apoptosis in mammalian cells?
What is the significance of the cell cycle?
What is the significance of the cell cycle?
Flashcards are hidden until you start studying
