Influenza Virus Genomic Sequences Quiz
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Questions and Answers

What is the function of PB1-F2 in some influenza viruses?

  • Aids in viral replication
  • Promotes host cell survival
  • Localizes to mitochondria and enhances apoptosis (correct)
  • Facilitates viral entry into the host cell

    • Which proteins are encoded by segment 7 of the influenza virus?

  • RNA polymerase subunits PA, PB1, PB2
  • Matrix M1 and envelope protein M2 (correct)
  • Non-structural proteins NS1 and NS2
  • Hemagglutinin and Neuraminidase

    • How is fusion of viral envelope with the endosomal membrane facilitated?

  • Viral envelope naturally fuses with endosome
  • Direct fusion upon contact
  • Activation by cleavage by cellular proteases (correct)
  • Endosomal pH change triggers fusion

    • What is the role of HA1 and HA2 subunits of Hemagglutinin (HA) in influenza virus?

    <p>HA1 is the surface subunit, binds to sialic acid; HA2 contains the fusion peptide</p> Signup and view all the answers

    Which of the following proteins are encoded by segments 1-6 of the influenza virus genome?

    <p>RNA polymerase subunits PA, PB1, and PB2</p> Signup and view all the answers

    What is the role of PB1-F2 in some influenza viruses?

    <p>Enhancing apoptosis by localizing to mitochondria</p> Signup and view all the answers

    How is fusion of viral envelope with the endosomal membrane facilitated in influenza virus?

    <p>Activation by cleavage by cellular proteases</p> Signup and view all the answers

    What is the function of the N-terminal region of Hemagglutinin (HA) in influenza virus?

    <p>It is exposed to the outside of the virion</p> Signup and view all the answers

    Which proteins are encoded by segment 8 of the influenza virus?

    <p>Non-structural proteins NS1 and NS2</p> Signup and view all the answers

    What is the role of PB1-F2 in some influenza viruses?

    <p>Localizes to mitochondria and enhances apoptosis</p> Signup and view all the answers

    How is fusion of viral envelope with the endosomal membrane facilitated in influenza virus?

    <p>Activation by cleavage by cellular proteases</p> Signup and view all the answers

    What is the function of the N-terminal region of Hemagglutinin (HA) in influenza virus?

    <p>Exposed to the outside of the virion</p> Signup and view all the answers

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