Influenza Virus Genomic Sequences Quiz

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12 Questions

What is the function of PB1-F2 in some influenza viruses?

Localizes to mitochondria and enhances apoptosis

Which proteins are encoded by segment 7 of the influenza virus?

Matrix M1 and envelope protein M2

How is fusion of viral envelope with the endosomal membrane facilitated?

Activation by cleavage by cellular proteases

What is the role of HA1 and HA2 subunits of Hemagglutinin (HA) in influenza virus?

HA1 is the surface subunit, binds to sialic acid; HA2 contains the fusion peptide

Which of the following proteins are encoded by segments 1-6 of the influenza virus genome?

RNA polymerase subunits PA, PB1, and PB2

What is the role of PB1-F2 in some influenza viruses?

Enhancing apoptosis by localizing to mitochondria

How is fusion of viral envelope with the endosomal membrane facilitated in influenza virus?

Activation by cleavage by cellular proteases

What is the function of the N-terminal region of Hemagglutinin (HA) in influenza virus?

It is exposed to the outside of the virion

Which proteins are encoded by segment 8 of the influenza virus?

Non-structural proteins NS1 and NS2

What is the role of PB1-F2 in some influenza viruses?

Localizes to mitochondria and enhances apoptosis

How is fusion of viral envelope with the endosomal membrane facilitated in influenza virus?

Activation by cleavage by cellular proteases

What is the function of the N-terminal region of Hemagglutinin (HA) in influenza virus?

Exposed to the outside of the virion

Test your knowledge of influenza virus genomic sequences, including conserved sequences, protein coding, and alternate splicing.

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