Questions and Answers
Which type of drugs are aminosalicylates?
Anti-inflammatory drugs
How do aminosalicylates like sulfasalazine work in the treatment of IBDs?
Topically in areas of diseased gastrointestinal mucosa
What is the main transcription factor that 5-ASA inhibits, leading to its anti-inflammatory effects?
NF-κB
What are the most common dose-related side effects of aminosalicylates like sulfasalazine?
Signup and view all the answers
What is the optimal dose range of sulfasalazine for achieving and maintaining remission in ulcerative colitis?
Signup and view all the answers
What risk is reduced by aminosalicylate maintenance therapy with doses of 1.2 g and above?
Signup and view all the answers
What is the principal type of inflammatory bowel disease that affects only the colon and rectum?
Signup and view all the answers
What is a possible cause of Ulcerative Colitis according to the text?
Signup and view all the answers
Which part of the digestive tract can Crohn's Disease affect?
Signup and view all the answers
What percentage of patients with Crohn's disease have ileocaecal disease according to the text?
Signup and view all the answers
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
