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Questions and Answers
Which type of drugs are aminosalicylates?
Which type of drugs are aminosalicylates?
- Antiviral drugs
- Antifungal drugs
- Anti-inflammatory drugs (correct)
- Antibiotics
How do aminosalicylates like sulfasalazine work in the treatment of IBDs?
How do aminosalicylates like sulfasalazine work in the treatment of IBDs?
- By enhancing the activity of natural killer cells
- By suppressing the immune system
- Systemically throughout the body
- Topically in areas of diseased gastrointestinal mucosa (correct)
What is the main transcription factor that 5-ASA inhibits, leading to its anti-inflammatory effects?
What is the main transcription factor that 5-ASA inhibits, leading to its anti-inflammatory effects?
- NF-κB (correct)
- TNF-alpha
- Cyclooxygenase
- Interleukin-6
What are the most common dose-related side effects of aminosalicylates like sulfasalazine?
What are the most common dose-related side effects of aminosalicylates like sulfasalazine?
What is the optimal dose range of sulfasalazine for achieving and maintaining remission in ulcerative colitis?
What is the optimal dose range of sulfasalazine for achieving and maintaining remission in ulcerative colitis?
What risk is reduced by aminosalicylate maintenance therapy with doses of 1.2 g and above?
What risk is reduced by aminosalicylate maintenance therapy with doses of 1.2 g and above?
What is the principal type of inflammatory bowel disease that affects only the colon and rectum?
What is the principal type of inflammatory bowel disease that affects only the colon and rectum?
What is a possible cause of Ulcerative Colitis according to the text?
What is a possible cause of Ulcerative Colitis according to the text?
Which part of the digestive tract can Crohn's Disease affect?
Which part of the digestive tract can Crohn's Disease affect?
What percentage of patients with Crohn's disease have ileocaecal disease according to the text?
What percentage of patients with Crohn's disease have ileocaecal disease according to the text?
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