Innate Immunity and Acute/Chronic Inflammation Quiz
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Questions and Answers

Which cells are responsible for secreting proinflammatory cytokines?

  • Mast cells (correct)
  • Eosinophils
  • Dendritic cells
  • Natural killer cells
  • Which cells are the principal cells that kill parasitic organisms?

  • Platelets
  • Eosinophils (correct)
  • Neutrophils
  • Macrophages
  • Which cells are involved in connecting the innate and acquired immune systems by collecting antigens at the site of inflammation?

  • Dendritic cells (correct)
  • Neutrophils
  • Macrophages
  • Endothelial cells
  • Which cells are the predominant phagocytic cells in the late inflammatory response and promote wound healing?

    <p>Macrophages</p> Signup and view all the answers

    Which cells are responsible for the elimination of pathogens and foreign debris through a multistep cellular process called phagocytosis?

    <p>Phagocytic cells</p> Signup and view all the answers

    Which cells are involved in synthesizing biochemical mediators such as histamine and chemotactic factors to initiate inflammation?

    <p>Mast cells</p> Signup and view all the answers

    Which cells are responsible for producing interferons when infected by viruses?

    <p>Lymphocytes</p> Signup and view all the answers

    Which cells regulate circulating components of the inflammatory system and maintain normal blood flow by preventing spontaneous activation of platelets and members of the clotting system?

    <p>Endothelial cells</p> Signup and view all the answers

    Which cells are responsible for inducing leukocyte chemotaxis?

    <p>Mast cells</p> Signup and view all the answers

    Which cells are the most important activators of the inflammatory response?

    <p>Mast cells</p> Signup and view all the answers

    Which cells are involved in the early inflammatory response by exiting the circulation and moving to the inflammatory site by chemotaxis?

    <p>Neutrophils</p> Signup and view all the answers

    Which cells are responsible for transporting antigens to sites such as the lymph nodes, where immunocompetent B and T cells reside?

    <p>Dendritic cells</p> Signup and view all the answers

    What are the macroscopic hallmarks of inflammation?

    <p>Redness, swelling, heat, pain, and loss of function</p> Signup and view all the answers

    Which plasma protein systems mediate inflammation?

    <p>Complement system, clotting system, and kinin system</p> Signup and view all the answers

    What activates the complement system?

    <p>Antigen-antibody reactions and bacterial polysaccharides</p> Signup and view all the answers

    Which products are the most biologically potent of the complement system?

    <p>C3b, C3a, and C5a</p> Signup and view all the answers

    What are the functions of the clotting system in inflammation?

    <p>Stops bleeding, localizes microorganisms, and provides a meshwork for repair and healing</p> Signup and view all the answers

    What is the most important product of the kinin system?

    <p>Bradykinin</p> Signup and view all the answers

    What is the microscopic hallmark of inflammation?

    <p>An accumulation of fluid and cells at the inflammatory site</p> Signup and view all the answers

    Inflammation can occur in which type of tissue?

    <p>Vascularized tissue</p> Signup and view all the answers

    What are the functions of C5a in the complement system?

    <p>Anaphylatoxin and chemotactic factor</p> Signup and view all the answers

    What activates the complement system through the lectin pathway?

    <p>Bacterial polysaccharides</p> Signup and view all the answers

    Which system causes vascular permeability, smooth muscle contraction, and pain?

    <p>Kinin system</p> Signup and view all the answers

    What are the key plasma protein systems that mediate inflammation?

    <p>Complement system, clotting system, and kinin system</p> Signup and view all the answers

    What are the principal systemic effects of inflammation?

    <p>Fever and increases in levels of circulating leukocytes and plasma proteins</p> Signup and view all the answers

    What characterizes chronic inflammation?

    <p>Dense infiltration of lymphocytes and macrophages</p> Signup and view all the answers

    What are the local manifestations of inflammation?

    <p>Redness, heat, swelling, and pain</p> Signup and view all the answers

    How long does chronic inflammation typically last?

    <p>2 weeks or longer</p> Signup and view all the answers

    What can occur as a distinct process without much preceding acute inflammation?

    <p>Chronic inflammation</p> Signup and view all the answers

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