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Questions and Answers
What is the primary condition associated with inflamed eyelid glands that can lead to infections?
What is the primary condition associated with inflamed eyelid glands that can lead to infections?
Blepharitis is the primary condition associated with inflamed eyelid glands that can lead to infections.
Identify the condition characterized by the loss of skin pigmentation, often affecting areas like the face and hands.
Identify the condition characterized by the loss of skin pigmentation, often affecting areas like the face and hands.
Vitiligo is characterized by the loss of skin pigmentation.
Define hypopyon and explain its significance in ocular health.
Define hypopyon and explain its significance in ocular health.
Hypopyon is the presence of white blood cells in the anterior chamber of the eye and indicates inflammation or infection.
What is the difference between hyphema and hypopyon?
What is the difference between hyphema and hypopyon?
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What is a common cause of elevated venous pressure in relation to eye health?
What is a common cause of elevated venous pressure in relation to eye health?
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What condition can result from the blockage of eyelid glands?
What condition can result from the blockage of eyelid glands?
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What is the significance of elevated venous pressure in relation to eye health?
What is the significance of elevated venous pressure in relation to eye health?
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Describe the role of antibiotics in treating eyelid infections.
Describe the role of antibiotics in treating eyelid infections.
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What are hypopyon and hyphema, and how do they differ?
What are hypopyon and hyphema, and how do they differ?
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What condition is characterized by loss of skin pigmentation, particularly on the face and hands?
What condition is characterized by loss of skin pigmentation, particularly on the face and hands?
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What are two common causes of conjunctival irritation that can lead to red eye?
What are two common causes of conjunctival irritation that can lead to red eye?
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Name a diagnostic procedure that helps assess the sharpness of vision in patients with red eye.
Name a diagnostic procedure that helps assess the sharpness of vision in patients with red eye.
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What is one effective method for managing blepharitis?
What is one effective method for managing blepharitis?
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What type of antibiotic is commonly used for treating dacrocystitis?
What type of antibiotic is commonly used for treating dacrocystitis?
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What symptoms are associated with uveitis, an ocular inflammation?
What symptoms are associated with uveitis, an ocular inflammation?
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Which diagnostic procedure can detect corneal abrasions or ulcers?
Which diagnostic procedure can detect corneal abrasions or ulcers?
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Describe one form of treatment for chronic dacrocystitis.
Describe one form of treatment for chronic dacrocystitis.
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What is the role of topical corticosteroids in managing ocular inflammation?
What is the role of topical corticosteroids in managing ocular inflammation?
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What are the primary symptoms of viral conjunctivitis?
What are the primary symptoms of viral conjunctivitis?
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How can allergic conjunctivitis typically be managed?
How can allergic conjunctivitis typically be managed?
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What type of discharge is associated with bacterial conjunctivitis?
What type of discharge is associated with bacterial conjunctivitis?
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What is a common cause of chlamydial conjunctivitis?
What is a common cause of chlamydial conjunctivitis?
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What factors contribute to the development of ophthalmia neonatorum in newborns?
What factors contribute to the development of ophthalmia neonatorum in newborns?
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What are the typical symptoms of allergic conjunctivitis?
What are the typical symptoms of allergic conjunctivitis?
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What is the standard treatment for bacterial conjunctivitis?
What is the standard treatment for bacterial conjunctivitis?
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How is viral conjunctivitis primarily transmitted?
How is viral conjunctivitis primarily transmitted?
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What is a pterygium, and what are its common causes?
What is a pterygium, and what are its common causes?
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How can pingueculum be distinguished from pterygium?
How can pingueculum be distinguished from pterygium?
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What characterizes a subconjunctival hemorrhage, and how is it typically treated?
What characterizes a subconjunctival hemorrhage, and how is it typically treated?
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What are the main symptoms of scleritis, and what can cause this condition?
What are the main symptoms of scleritis, and what can cause this condition?
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Describe the symptoms of episcleritis and how it can be treated.
Describe the symptoms of episcleritis and how it can be treated.
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What is the typical course of treatment for a symptomatic pterygium?
What is the typical course of treatment for a symptomatic pterygium?
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What risk factors are associated with the development of pingueculum?
What risk factors are associated with the development of pingueculum?
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How can one differentiate between scleritis and episcleritis?
How can one differentiate between scleritis and episcleritis?
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What are the common causes of keratitis in contact lens wearers?
What are the common causes of keratitis in contact lens wearers?
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Explain how anterior uveitis can affect the pupil's appearance.
Explain how anterior uveitis can affect the pupil's appearance.
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What is the primary symptom of severe uveitis that affects patients' quality of life?
What is the primary symptom of severe uveitis that affects patients' quality of life?
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Identify the series of symptoms that may indicate the presence of a corneal ulcer.
Identify the series of symptoms that may indicate the presence of a corneal ulcer.
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Describe the relationship between keratitis and inflammation of the eye.
Describe the relationship between keratitis and inflammation of the eye.
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What steroid therapy strategy is commonly used to manage anterior uveitis?
What steroid therapy strategy is commonly used to manage anterior uveitis?
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What is a potential serious complication of untreated anterior necrotizing scleritis?
What is a potential serious complication of untreated anterior necrotizing scleritis?
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How can hypopyon serve as an indicator in the assessment of uveitis?
How can hypopyon serve as an indicator in the assessment of uveitis?
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What is a potential complication of blepharitis that affects the cornea?
What is a potential complication of blepharitis that affects the cornea?
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What are the classic signs of corneal involvement in blepharitis?
What are the classic signs of corneal involvement in blepharitis?
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How does meibomian gland dysfunction relate to keratitis?
How does meibomian gland dysfunction relate to keratitis?
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What inflammatory condition can occur in the anterior segment of the eye and may involve the ciliary body?
What inflammatory condition can occur in the anterior segment of the eye and may involve the ciliary body?
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What are the possible causes of recurrent epithelial erosion associated with blepharitis?
What are the possible causes of recurrent epithelial erosion associated with blepharitis?
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In cases of severe inflammation in uveitis, what symptom may predominantly affect pupil response?
In cases of severe inflammation in uveitis, what symptom may predominantly affect pupil response?
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What is a distinguishing feature of keratitis related to infection from blepharitis?
What is a distinguishing feature of keratitis related to infection from blepharitis?
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What role do bacteria like Staphylococcus aureus play in affecting eyelid and corneal health?
What role do bacteria like Staphylococcus aureus play in affecting eyelid and corneal health?
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What distinguishes scleritis from episcleritis in terms of vasculature response to 2.5% phenylephrine drops?
What distinguishes scleritis from episcleritis in terms of vasculature response to 2.5% phenylephrine drops?
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What is a potential serious complication of untreated scleritis?
What is a potential serious complication of untreated scleritis?
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Describe the typical pain experience of a patient with scleritis.
Describe the typical pain experience of a patient with scleritis.
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What common ocular condition can present with a bright maroon red area in fresh hemorrhage?
What common ocular condition can present with a bright maroon red area in fresh hemorrhage?
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How does the treatment approach differ between episcleritis and scleritis?
How does the treatment approach differ between episcleritis and scleritis?
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What is the characteristic color and texture of nodules found in nodular scleritis?
What is the characteristic color and texture of nodules found in nodular scleritis?
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What symptom often accompanies uveitis that affects measurement of visual acuity?
What symptom often accompanies uveitis that affects measurement of visual acuity?
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In uveitis, what is the significance of the appearance of hypopyon?
In uveitis, what is the significance of the appearance of hypopyon?
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Study Notes
Inflammation of the eyelid
- Oculoglandular syndrome is also known blepharitis
- Infection of the meibomian glands produces blocked sebaceous glands
- Can be bacterial or viral in origin
- Infection of the glands can cause chalazia
- Infection of the glands can cause sty
- The infection of the glands can cause inflammation and swelling
Signs and Symptoms
- Infection can cause redness and edema
- The eyelids can also feel itchy
- Can also get foreign body sensation
- Can lead to excess tears
- Can be related to conjunctivitis
- Can be associated with dry eye
Treatment
- Warm compress can help
- Cleaning the eyelids regularly can help
- Artificial tears and lubricants can help
- Steroid drops or ointment can help
- Antibiotics are effective
- Oral antibiotics can be given if the infection is widespread
- Surgery is needed for chalazion if it does not improve
Inflammation of the cornea
- This condition is called keratitis
- It can be caused by infection and inflammation
- It can cause pain
- It can also cause photophobia
- It can cause blurred vision
Treatment
- Depends on the cause
- Antibiotics may be necessary
- Steroid drops may be necessary
- Surgery may be required, depending on the cause
Internal inflammation of the eye
- uveitis is any inflammation of the uvea that can include the iris, ciliary body, and choroid
- Can cause pain and blurred vision
- Can be caused by infection, injury, or autoimmune disorders
- Treatment involves steroids and antibiotics
- Surgery, in some cases, may be required.
Acne-Prone Blepharitis
- Blepharitis is an inflammation of the eyelids, often due to blocked oil glands.
- The condition can be associated with acne.
Preseptal Cellulitis
- This is an infection of tissues around the eye, but not the eye itself.
- Symptoms may include redness, swelling, and pain in the eyelid area.
- Treatment typically involves antibiotics.
Vitiligo
- This autoimmune disorder causes loss of skin pigment, resulting in patches of lighter skin.
Polio
- A viral infection that can cause paralysis.
- Vaccines are available to prevent polio.
Tensor Fasciae Latae
- A muscle in the thigh that helps with hip extension and hip abduction.
Eyelid Inflammation
- Inflammation of the eyelids can be caused by infection, allergies, or irritation.
- Symptoms may include redness, swelling, itching, and discharge.
Corneal Inflammation
- Inflammation of the cornea, the clear outer layer of the eye.
- Symptoms may include pain, blurred vision, redness, and sensitivity to light.
Uveitis
- Inflammation of the uvea, the middle layer of the eye.
- Symptoms may include pain, blurred vision, and sensitivity to light.
Hypopyon
- White blood cells in the anterior chamber of the eye, a sign of inflammation.
Hyphema
- Red blood cells in the anterior chamber of the eye, a sign of bleeding.
Medication Notes
- Phenylephrine is a vasoconstrictor that can be used in eye drops to reduce redness and swelling.
- Trabeton is a medication used to treat glaucoma, by reducing intraocular pressure.
- Antibiotics may be used to treat infections, given by injection (IV) or orally.
Other Notes
- "Beefy" appearance of the eye may be a sign of inflammation.
- Wateriness of the eye can be a sign of irritation or infection.
- Elevated venous pressure - Possible cause for inflammation around the eye.
- Blocked oil glands of the eyelids can contribute to blepharitis.
- Information regarding specific conditions and treatments can be found from reliable sources.
Causes of Red Eye
- Red eye can be triggered by irritation, infections, or underlying systemic conditions.
- Common causes include conjunctivitis (viral or bacterial), allergies, eye irritants, and subconjunctival hemorrhage.
- Other causes include corneal conditions, such as ulcers, and eye pressure changes, like angle-closure glaucoma.
- Systemic conditions, like hypertension or autoimmune disorders, can also manifest as red eye.
Diagnosing Red Eye
- A thorough medical history, including symptom duration and severity, is a crucial part of diagnosis.
- Visual acuity tests assess vision sharpness.
- Slit-lamp examination offers a detailed view of the conjunctiva, cornea, and anterior chamber.
- Fluorescein staining helps detect corneal abrasions or ulcers.
- Intraocular pressure measurement is essential to rule out glaucoma.
- Cultures and sensitivity tests, if indicated, help identify and treat infectious causes.
Managing Blepharitis
- Maintaining excellent eyelid hygiene is crucial, including warm compresses and gentle scrubs.
- Topical antibiotics like bacitracin or erythromycin ointments are used for bacterial infections.
- Oral antibiotics, such as doxycycline, are prescribed in severe or chronic cases.
- Steroid drops help manage chronic inflammation with significant symptoms.
- Regular eyelid hygiene is essential for preventing recurrent blepharitis.
Treating Dacrocystitis
- Antibiotic therapy with broad-spectrum oral medications (cephalexin) is common.
- Warm compresses aid in symptom relief and promote drainage.
- Surgical intervention, known as dacryocystorhinostomy (DCR), may be required for chronic cases or abscess formation.
- Lacrimal sac massage aids in drainage for some individuals.
Ocular Inflammation
- Uveitis, inflammation of the uvea, presents with pain, photophobia, and red eye.
- Scleritis, inflammation of the sclera, causes severe pain and potential vision loss.
- Management typically includes topical corticosteroids to reduce inflammation.
- Systemic therapy, involving oral steroids or immunosuppressants, is used for severe cases.
- Referrals to specialists are necessary for underlying systemic conditions, such as autoimmune diseases.
- Regular follow-up care is essential to monitor for complications and progression of inflammation.
Conjunctivitis
- Inflammation of the conjunctiva, the transparent membrane covering the white part of the eye and inside the eyelids.
- Commonly known as "pink eye".
Viral Conjunctivitis
- Typically caused by adenoviruses, often following a respiratory infection.
- Characterized by watery discharge, redness in the eye, itching or discomfort, affecting one or both eyes.
- Highly contagious, spreading through direct contact or contaminated surfaces.
- No specific antiviral treatment, supportive care includes warm compresses and artificial tears.
Allergic Conjunctivitis
- Triggered by allergens such as pollen, dust mites, pet dander, or mold
- Symptoms include itchy, red, watery eyes, swelling of the conjunctiva, typically affecting both eyes.
- Managed through antihistamines (oral or eye drops) and avoidance of allergens, cool compresses can provide relief.
Bacterial Conjunctivitis
- Caused by various bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae.
- Presents with thick, yellow or green pus-like discharge, redness and swelling, crusting of eyelids, especially upon waking.
- Can be contagious, often spread via direct contact.
- Treated with antibiotic eye drops or ointments.
Chlamydial Conjunctivitis
- Caused by infection with Chlamydia trachomatis, often linked to sexually transmitted infections.
- Features redness, discharge (can be watery), and irritation, often chronic and requiring treatment to avoid complications.
- Transmitted through sexual contact or from mother to baby during birth.
- Treated with oral antibiotics, such as azithromycin or doxycycline.
Ophthalmia Neonatorum
- Conjunctivitis in newborns, commonly caused by bacteria like Neisseria gonorrhoeae, Chlamydia trachomatis, or chemical irritants (like silver nitrate).
- Exhibits red, swollen eyes, purulent discharge, occurring within the first month of life.
- Requires prompt evaluation and treatment to prevent complications.
- Antibiotic therapy is administered based on the identified causative organism.
Pterygium
- Triangular growth of fibrovascular tissue on the conjunctiva
- Occurs due to prolonged UV exposure, dry environments, and chronic irritation
- Causes redness, irritation, and vision obstruction when it grows over the cornea
- Small pterygia are usually monitored; surgical removal is done for larger or symptomatic pterygia
Pingueculum
- Yellowish, raised growth on the conjunctiva, most commonly on the nasal side
- Often associated with aging and UV exposure
- Generally asymptomatic; can cause irritation or dryness
- Artificial tears are used for irritation; surgical removal is performed in severe cases
Subconjunctival Hemorrhage
- Leakage of blood between the conjunctiva and sclera
- Caused by trauma, hypertension, bleeding disorders, and straining
- Appears as a bright red patch on the white of the eye, usually painless
- Usually self-limiting and resolves without treatment; recurrent or painful cases may require further evaluation
Scleritis
- Inflammation of the sclera (white outer coating of the eyeball)
- Caused by autoimmune diseases, infections, or unknown causes
- Characterized by severe pain, redness, vision changes, and the possibility of nodules
- Treated with NSAIDs or corticosteroids; immunosuppressive therapy may be necessary in some cases
Episcleritis
- Inflammation of the episclera (tissue between the sclera and conjunctiva)
- Characterized by mild pain, discomfort, localized redness, and swelling
- Usually benign and comes in simple or nodular forms
- Often resolves on its own; persistent cases may be treated with NSAIDs or topical corticosteroids
Keratitis
- Inflammation of the cornea
- Caused by infections (bacterial, viral, fungal), contact lens wear, and trauma
- Symptoms include pain, redness, vision changes, tearing, and sensitivity to light
- Treatment depends on the cause; antimicrobial drops are used for infections, along with supportive care
Corneal Ulcer
- Open sore on the cornea, often due to infection
- Symptoms include severe pain, redness, discharge, blurred vision, and light sensitivity
- Risk factors include contact lens use, previous eye injury, and dry eyes
- Requires urgent care; treated with antibacterial, antifungal, or antiviral eye drops depending on the cause
Uveitis
- Inflammation of the uveal tract (iris, ciliary body, choroid)
- Caused by autoimmune diseases, infections, trauma, or unknown causes
- Symptoms include eye redness, pain, light sensitivity, blurred vision, and floaters
- Treated with corticosteroids, dilating drops, and management of underlying causes
Scleritis
- A painful inflammation of the sclera, the white part of the eye.
- Often occurs in the upper temporal quadrant
- More common in females, usually presents in the 5th decade
- Deep, aching pain that may spread to the face, jaw, and temple
- Pain is worse in the early morning hours and improves later in the day.
- Responds poorly to common analgesics.
Types of Scleritis
-
Non-necrotizing scleritis:
- Less severe, less destructive
- May be diffuse (generalized redness) or nodular (single or multiple nodules)
-
Necrotizing scleritis:
- More aggressive, can lead to severe visual morbidity
- Pain is persistent and severe
- Can be associated with rheumatoid arthritis, Wegener's granulomatosis, or surgically-induced
Treatment for Scleritis
- Topical steroids: Relieve symptoms and oedema in non-necrotizing scleritis
- Systemic NSAIDs: Relief of pain or regression of physical signs
- Periocular steroid injections: When NSAIDs are ineffective
-
Systemic steroids: Used when NSAIDs are inappropriate or ineffective (necrotizing scleritis)
- Prednisolone dose is 1.0–1.5 mg/kg/day
- Immune modulators: Such as ciclosporin and tacrolimus
-
Cytotoxic agents: For example cyclophosphamide, azathioprine, mycophenolate mofetil, and methotrexate
- Used when scleritis is not completely controlled with steroids alone
- Used as a steroid-sparing measure in patients requiring long-term treatment
- Used in patients with an underlying systemic vasculitis - can be life-saving
Oedema
- May subside with treatment.
- Slight grey/blue appearance may occur due to increased translucency of the sclera
Anterior Necrotizing Scleritis
- Serious and aggressive form of scleritis
- Later onset than other forms
- May result in permanent visual loss
Anterior Uveitis
- Inflammation of the front part of the uvea, the middle layer of the eye.
- Can cause reduced visual acuity
- Signs include:
- Redness around the limbus (ciliary injection or ciliary flush)
- Ocular pain
- Photophobia
- Blurred vision
- Can lead to damage to the macula and optic nerve
Anterior Uveitis Treatment
- Mainstay of treatment is steroid therapy
- Aims are to:
- Suppress inflammation in the eye
- Relieve symptoms
- Prevent damage to ocular structures
Pupil Shape, Size, and Reaction
- In iritis, spasm of the iris sphincter muscles may cause the pupil to be smaller in the affected eye or distorted.
- The pupil may be fixed and mid-dilated in acute angle closure glaucoma
Blepharitis
- Inflammation of the eyelid and eyelid margin
- Usually bilateral and symmetrical
- Subdivided into anterior and posterior blepharitis
Anterior Blepharitis
- Inflammation of the area surrounding the eyelash bases
- Abnormal cell-mediated response to components of the S. aureus cell wall
Symptoms
- Burning, grittiness, mild photophobia
- Crusting and redness of the lid margins
- Remissions and exacerbations
Signs
- Hard scales and crusting around the base of lashes (collarettes) (staph)
- Soft scales and greasy anterior lid margins with sticking together of lashes (seborrhoeic)
Posterior Blepharitis
- Affects the meibomian glands within the eyelid
- Meibomian gland dysfunction (MGD)
- Results from bacterial enzymes from S. epidermidis, S. aureus, and Propionibacterium acnes
Symptoms
- Burning, grittiness, mild photophobia
- Crusting and redness of the lid margins
- Remissions and exacerbations
Signs
- Capping or plugging of the meibomian gland orifices
- Dryness, oily, and froth on the lid margins
- Hyperaemia and telangiectasis on the eyelid
- Scarring and notching in long-standing cases
- Mild papillary conjunctivitis
- Inferior corneal punctate epithelial erosions
Blepharitis Complications
- Tear film instability: Imbalance between aqueous and lipid components of the tear film, leading to increased evaporation.
- Cutaneous: Acne rosacea (MGD) and Seborrhoeic dermatitis (seborrhoeic blepharitis) >90%
- Lid: External hordeolum (stye) or internal hordeolum (painful, tender, red nodular masses near the eyelid margin), Chalazion formation
- Cornea: Bacterial or marginal keratitis, recurrent epithelial erosion
- Conjunctivae: Phlyctenulosis (rounded, elevated, gray or yellow, hyperemic, focal inflammatory nodules accompanied by a zone of engorged hyperemic vessels)
- Contact lens intolerance
- Inhibition of lid movement
Blepharitis Treatment
- Lid hygiene: Gentle cleansing of the eyelid margins
- Antibiotics: Topical sodium fusidic acid or chloramphenicol
- Medical: Tear substitutes and topical steroids for inflammation
- Sunglasses: To reduce ultraviolet exposure and decrease growth stimulus
Epicanthus
- A fold of skin that covers the inner corner of the eye.
- Can be a normal variant or a sign of a condition.
Subconjunctival Haemorrhage
- Blood beneath the conjunctiva causing a bright maroon red appearance.
- May be idiopathic or caused by:
- Hypertension
- Valsalva maneuver (coughing, constipation, heavy lifting)
- Bleeding diathesis
- Anticoagulants
- Trauma
- Haemorrhage without a posterior margin may be associated with an intracranial bleed.
- Check BP and IOP.
- If recurrent, request coagulation screen and FBC.
- Treatment is usually not required as the haemorrhage will fade over 2 weeks.
- Refer to a haematologist if a bleeding diathesis is detected or a general practitioner if hypertensive.
Episcleritis
- Inflammation of the episclera, the thin layer of tissue between the sclera and conjunctiva.
- Redness that can be sectoral, diffuse, or nodular
- Interpalpebral distribution
- Usually peaks within 12 hours and then gradually fades over a few days
Episcleritis Treatment
- Cool artificial tears may be sufficient in some cases
- A weak topical steroid q.i.d. for 1–2 weeks is usually sufficient
Differentiation from Episcleritis
- Instillation of 2.5% phenylephrine drops will constrict the conjunctival and superficial episcleral vasculature (episcleritis) but not the deep plexus (scleritis).
Keratitis/Ulcer
- Inflammation or ulceration of the cornea.
- Can be caused by:
- Infection (bacterial, viral, fungal, protozoal)
- Mechanical or trauma (foreign body)
- Chemical (alkali injuries are worse than acid)
Classification of Scleritis
- Diffuse scleritis: Generalized oedema with vascular congestion and dilatation.
- Nodular scleritis: Single or multiple nodules, usually developing in the interpalpebral region. These have a deeper blue-red colour than episcleral nodules and are immobile.
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Description
This quiz covers the conditions related to inflammation of the eyelid, including blepharitis and its causes, signs, symptoms, and treatments. It also touches upon keratitis and its implications. Test your knowledge on eye infections and their management!