Inflammation and Immune Response Molecules Quiz
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Questions and Answers

Which of the following is a common symptom of asthma?

  • Joint pain
  • Abdominal pain
  • Shortness of breath (correct)
  • Fever
  • What is the prevalence of asthma in the United States?

  • 8.4%
  • 7.9% (correct)
  • 7.3%
  • 4.3%
  • Which gender has a higher prevalence of asthma in childhood?

  • Girls
  • Not mentioned in the text
  • Equal prevalence in both genders
  • Boys (correct)
  • What is the most common type of airway inflammation in asthma?

    <p>Eosinophilic</p> Signup and view all the answers

    Which cytokine has a critical role in regulating eosinophils?

    <p>IL-5</p> Signup and view all the answers

    Which type of inflammation is commonly seen in severe asthma that has not responded to corticosteroids?

    <p>Neutrophilic inflammation</p> Signup and view all the answers

    Which chemical substance is produced by mast cells and upregulates type 2 inflammation?

    <p>Prostaglandins</p> Signup and view all the answers

    Which fatty acid mediator is responsible for the resolution of inflammation?

    <p>Interleukins</p> Signup and view all the answers

    Which of the following is NOT a mediator involved in type 2 and non-type 2 inflammation?

    <p>Resolvins</p> Signup and view all the answers

    What is the percentage range of heritability suggested by family and twin studies?

    <p>25-50%</p> Signup and view all the answers

    Which of the following is NOT a gene consistently identified in association studies with asthma?

    <p>IL-12</p> Signup and view all the answers

    What proportion of asthma risk can be explained by the currently identified 31 single nucleotide polymorphisms associated with asthma?

    <p>2%</p> Signup and view all the answers

    Which country had the highest asthma mortality rate in 2006?

    <p>Unknown</p> Signup and view all the answers

    What is the estimated economic cost of asthma in the United States in 2016?

    <p>$1.8 million</p> Signup and view all the answers

    Which race is associated with greater case morbidity in asthma?

    <p>Unknown</p> Signup and view all the answers

    What is the most common trigger of airway narrowing in asthma?

    <p>Exercise</p> Signup and view all the answers

    Which type of inflammation is associated with the production of cytokines interleukin (IL) 4, IL-5, and IL-13?

    <p>Type 2 inflammation</p> Signup and view all the answers

    What is the main characteristic of airway inflammation in most asthmatics?

    <p>Eosinophilic inflammation</p> Signup and view all the answers

    What can contribute to airway obstruction in asthma?

    <p>All of the above</p> Signup and view all the answers

    What can the deposition of collagen and matrix in the airway result in?

    <p>Exaggerated responses to increased circumferential tension</p> Signup and view all the answers

    What is the estimated percentage of adult-onset asthma that is attributed to occupational exposures?

    <p>25%</p> Signup and view all the answers

    Which of the following is NOT a recognized type of occupational asthma?

    <p>Immunologic stimuli</p> Signup and view all the answers

    Which of the following is associated with increased risk of children developing asthma symptoms?

    <p>Air pollution</p> Signup and view all the answers

    Which of the following is believed to cause oxidative injury to the airways, producing airway inflammation and leading to remodeling and increased risk of airway sensitization?

    <p>Air pollution</p> Signup and view all the answers

    Which of the following has been suggested as a risk factor for childhood and adult asthma?

    <p>All of the above</p> Signup and view all the answers

    What is the association between H2 blockers and proton pump inhibitors use in pregnancy and the risk of asthma in children?

    <p>Increased risk of asthma</p> Signup and view all the answers

    What did a study from NHANES II find regarding the association between obesity and asthma?

    <p>Association with dyspnea but not with airway obstruction</p> Signup and view all the answers

    What is the association between perinatal acetaminophen use and the risk of asthma?

    <p>No association found</p> Signup and view all the answers

    Which of the following has been suggested as playing a pathobiologic role in the development of asthma?

    <p>Both adipokines and IL-6</p> Signup and view all the answers

    What is the association between maternal polyunsaturated fatty acid supplementation and childhood asthma risk?

    <p>Decreased risk of asthma</p> Signup and view all the answers

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