Infective Endocarditis Diagnosis Criteria
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Questions and Answers

What are some peripheral manifestations of infective endocarditis?

Petechiae, Osler nodes, Janeway lesions, splinter hemorrhages, Roth spots

What is the significance of fever and heart murmurs in the presence of positive blood culture?

They are signs of infective endocarditis.

Describe Osler nodes and Janeway lesions.

Osler nodes are small, tender, subcutaneous nodules in the digits, while Janeway lesions are small, erythematous or hemorrhagic macular nontender lesions on the palms and soles.

What are Roth spots in the context of infective endocarditis?

<p>Oval retinal hemorrhages with pale centers.</p> Signup and view all the answers

How can splinter hemorrhages in the nail beds be linked to a medical condition?

<p>They can be a sign of infective endocarditis.</p> Signup and view all the answers

What are some oral abnormalities associated with infective endocarditis?

<p>Petechiae of the palpebral conjunctiva, the buccal and palatal mucosa, splinter hemorrhages, Roth spots</p> Signup and view all the answers

What are the definitive criteria for diagnosing infective endocarditis (IE)?

<p>Presence of two major criteria, one major and three minor criteria, or five minor criteria</p> Signup and view all the answers

What is considered a major criterion for diagnosing infective endocarditis (IE)?

<p>Positive blood cultures or evidence of endocardial involvement</p> Signup and view all the answers

What are examples of minor criteria for diagnosing infective endocarditis (IE)?

<p>Predisposing heart condition or IV drug use, fever, vascular phenomena, immunologic phenomena, microbiologic evidence</p> Signup and view all the answers

What is the treatment for infective endocarditis (IE)?

<p>Antibiotics; in severe cases, early removal of infected valves and insertion of a sterile replacement</p> Signup and view all the answers

What are the general guidelines for dental prophylaxis in patients with infective endocarditis risk?

<p>Good oral hygiene and antibiotic prophylaxis for certain dental procedures</p> Signup and view all the answers

Which dental procedures require antibiotic prophylaxis in patients at risk for infective endocarditis?

<p>All dental procedures except routine anesthetic injections through non-infected tissue, dental radiographs, placement of removable prosthodontic or orthodontic appliances, adjustment of orthodontic appliances, shedding of deciduous teeth, and bleeding from trauma to the lips or oral mucosa</p> Signup and view all the answers

According to AHA 2017 guidelines, which patients should receive antibiotic prophylaxis for dental procedures?

<p>Patients with prosthetic cardiac valves, prosthetic material used for cardiac valve repair, or a history of infective endocarditis</p> Signup and view all the answers

What are some complications associated with infective endocarditis?

<p>Heart failure, embolization, stroke, myocardial infarction, peripheral abscesses, failure of organs, septic shock, invasive infection, prosthetic valve dehiscence, heart block, mycotic aneurysm, and death.</p> Signup and view all the answers

Which are the most common causative agents of infective endocarditis?

<p>Streptococci and Staphylococci.</p> Signup and view all the answers

What is the most possible mechanism for the development of infective endocarditis?

<p>Injury to the endothelium near an anatomic defect or prosthesis, leading to the formation of non-bacterial thrombotic endocarditis.</p> Signup and view all the answers

How do platelets and fibrin play a role in infective endocarditis?

<p>They adhere to the injured endothelium, forming masses known as vegetations which protect bacteria from antibiotics.</p> Signup and view all the answers

What is the process by which bacteria multiply and release from vegetations into the bloodstream in infective endocarditis?

<p>Bacterial multiplication occurs within the vegetations, and fragments of the vegetation embolize into the bloodstream.</p> Signup and view all the answers

What are some hospital-based settings where Staphylococci are more common as causative agents of infective endocarditis?

<p>Intravenous drug users and hospital settings.</p> Signup and view all the answers

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